Elsevier

The Lancet

Volume 307, Issue 7962, 3 April 1976, Pages 709-711
The Lancet

PLASMAPHERESIS IN THE MANAGEMENT OF ACUTE SYSTEMIC LUPUS ERYTHEMATOSUS?

https://doi.org/10.1016/S0140-6736(76)93088-9Get rights and content

Abstract

Eight patients with systemic lupus erythematosus (S.L.E.) have been treated with plasmapheresis. In four patients in whom immunochemical studies indicated high levels of circulating immune complexes, the removal of 5—8 litres of plasma weekly produced a striking clinical and immunochemical improvement. The four other patients, with only minor complement disturbances and no direct evidence of circulating immune complexes, could not be shown to ben-

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