Biochimica et Biophysica Acta (BBA) - General Subjects
Chemical and biological characterization of oxo-eicosatetraenoic acids
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Cited by (38)
Targeting the OXE receptor as a potential novel therapy for asthma
2020, Biochemical PharmacologyBiosynthesis, biological effects, and receptors of hydroxyeicosatetraenoic acids (HETEs) and oxoeicosatetraenoic acids (oxo-ETEs) derived from arachidonic acid
2015, Biochimica et Biophysica Acta - Molecular and Cell Biology of LipidsThe eosinophil chemoattractant 5-oxo-ETE and the OXE receptor
2013, Progress in Lipid ResearchCitation Excerpt :The responses of neutrophils to 5-oxo-ETE are very similar to those of eosinophils, including chemotaxis [91], calcium mobilization [91,92], actin polymerization [93,94], and CD11b expression [94]. 5-Oxo-ETE also promotes neutrophil aggregation [95], adherence, and increased surface expression of CD11c [94]. In contrast to eosinophils, unprimed neutrophils generate little [93] or no [96] superoxide in response to 5-oxo-ETE.
Twelve oxo-eicosatetraenoic acid induces fetal membrane release after delivery in cows
2012, PlacentaCitation Excerpt :The identified cascade of 12-oxoETE is as follows: 12-LOX basically converts Ara to 12-HPETE; however, it can produce 12-oxoETE directly [26,27]. If 12-HPETE converts to 12-HETE by reductase, it can be changed to 12-oxoETE by dehydrogenase [26]. Ara is released from the placenta membrane by phospholipase for prostaglandin synthesis at delivery, so it is expected that the same mechanism supplies Ara to fibroblasts and converts to 12-oxoETE.
5-Oxo-15-HETE: Total synthesis and bioactivity
2011, Bioorganic and Medicinal Chemistry Letters5-Oxo-ETE and the OXE receptor
2009, Prostaglandins and Other Lipid Mediators