Full paperGermline autonomy of maternal-effect mutations altering the embryonic body pattern of Drosophila☆
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2021, Animal Reproduction ScienceCitation Excerpt :Also known as ddx4, the vasa gene encodes for a member of a family of ATP-dependent RNA helicases that belongs to the DEAD (Asp–Glu–Ala–Asp)-box protein family. The vasa mRNA transcript has been detected in the germ cells of a wide range of organisms (Schupbach and Wieschaus, 1986; Hay et al., 1988; Liang et al., 1994; Olsen et al., 1997; Castrillon et al., 2000). In teleosts, there is a large abundance of vasa that can be evaluated for the identification of germ cell lineages, including PGC, ASGs, and oogonia, in various species (Braat et al., 2004).
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This research was supported by United States Public Health Service Grant 5RO1 HD15587 to Eric Wieschaus, by Swiss National Science Foundation Grant 3.460.79 to R. Nöthiger, and by a postdoctoral fellowship from the Swiss National Science Foundation.