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Photonic crystal based biosensors: an overview

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Abstract

Photonic Crystals (PC) have emerged as interesting photonic structures for the past few decades and play a vital role in the field of optical communication, biomedical sensing, and other applications. Photonic crystals have a major impact in designing the variety of photonic sensors due to its compactness, high sensitivity, high selectivity, fast responsiveness, immunity to electromagnetic noise, etc. The physical property of the photonic crystals is altered to create the sensors for various applications such as temperature, pressure, stress, gas, chemical, biomaterials, etc. PC-based biosensors assure fast response, high accuracy, good quality factor with low losses. Several sensing schemes such as, Surface plasmon resonance, Infra-Red (IR) absorption, Refractive index sensing, and Displacement sensing are used and being explored using different PC design structures. The Effective Refractive Index sensing is the most common sensing mechanism used in Biosensor and optical properties of the sensors are analyzed by comparing the spectral properties of the transmitted and reflected power. This review article aims to discuss about the recent developments in PC-based biosensors with different design structures, analysis, and different analytes, biomaterials. Further, the comparison of the design, structural and performance parameters of various biosensors are tabulated.

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References

  • Ameta S, Sharma A, Inaniya PK (2017a) Nanocavity coupled waveguide photonic crystal biosensor for detection of different blood components. In: 2017 international conference on computing, communication and automation (ICCCA) (pp 1554–1557). IEEE

  • Ameta S, Sharma A, Inaniya PK (2017b) Designing a multichannel nanocavity coupled photonic crystal biosensor for detection of glucose concentration in blood. In: 2017 8th international conference on computing, communication and networking technologies (ICCCNT) (pp 1–4). IEEE

  • Arafa S, Bouchemat M, Bouchemat T, Benmerkhi A, Hocini A (2017) Infiltrated photonic crystal cavity as a highly sensitive platform for glucose concentration detection. Opt Commun 384:93–100

    Article  Google Scholar 

  • Areed NF, Hameed MFO, Obayya SSA (2017) Highly sensitive face-shaped label-free photonic crystal refractometer for glucose concentration monitoring. Opt Quant Electron 49(1):1–12. https://doi.org/10.1007/s11082-016-0847-9

    Article  Google Scholar 

  • Arunkumar R, Suaganya T, Robinson S (2019) Design and analysis of 2D photonic crystal based biosensor to detect different blood components. Photon Sensors 9(1):69–77

    Article  Google Scholar 

  • Bahaddur I, Tejaswini MR, Santhosh Kumar TC, Sharan P, Srikanth PC (2019) 2D Photonic crystal cantilever resonator pressure sensor. In: 2019 workshop on recent advances in photonics (WRAP) (pp 1–4). IEEE

  • Balaji VR, Murugan M, Robinson S (2016) Two-dimensional photonic crystal assisted DWDM demultiplexer with uniform channel spacing. Dig J Nanomater Biostruct 11(4)

  • Bayindir M, Temelkuran B, Ozbay EJAPL (2000) Photonic-crystal-based beam splitters. Appl Phys Lett 77(24):3902–3904

    Article  Google Scholar 

  • Bougriou F, Boumaza T, Bouchemat M (2014) Design of photonic crystals waveguide using microfluidic infiltration. In: Applied mechanics and materials (vol 492, pp 301–305). Trans Tech Publications Ltd

  • Chao CY, Fung W, Guo LJ (2006) Polymer microring resonators for biochemical sensing applications. IEEE J Sel Top Quantum Electron 12(1):134–142

    Article  Google Scholar 

  • Chhipa MK, Robinson S, Radhouene M, Najjar M, Srimannarayana K (2017) 2D photonic crystal micro cavity ring resonator based sensor for biomedical applications. In: 2017 conference on lasers and electro-optics pacific rim (CLEO-PR) (pp 1–2). IEEE

  • Chopra H, Kaler RS, Painam B (2016) Photonic crystal waveguide-based biosensor for detection of diseases. J Nanophoton 10(3):036011

    Article  Google Scholar 

  • Chow E, Grot A, Mirkarimi LW, Sigalas M, Girolami GJOL (2004) Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity. Opt Lett 29(10):1093–1095

    Article  Google Scholar 

  • Clark LC Jr, Lyons C (1962) Electrode systems for continuous monitoring in cardiovascular surgery. Ann N Y Acad Sci 102(1):29–45

    Article  Google Scholar 

  • Harhouz A, Hocini A (2015) Design of high-sensitive biosensor based on cavity-waveguides coupling in 2D photonic crystal. J Electromagnet Waves Appl 29(5):659–667

    Article  Google Scholar 

  • Hocini A, Harhouz A (2016) Modeling and analysis of the temperature sensitivity in two-dimensional photonic crystal microcavity. J Nanophotonics 10(1):016007. https://doi.org/10.1117/1.JNP.10.016007

    Article  Google Scholar 

  • Huang L, Tian H, Yang D, Zhou J, Liu Q, Zhang P, Ji Y (2014) Optimization of figure of merit in label-free biochemical sensors by designing a ring defect coupled resonator. Opt Commun 332:42–49. https://doi.org/10.1016/j.optcom.2014.06.033i

    Article  Google Scholar 

  • Jindal S, Sobti S, Kumar M, Sharma S, Pal MK (2016) Nanocavity-coupled photonic crystal waveguide as highly sensitive platform for cancer detection. IEEE Sens J 16(10):3705–3710

    Article  Google Scholar 

  • Joannopoulos JD, Villeneuve PR, Fan S (1997) Photonic crystals: putting a new twist on light. Nature 386(6621):143–149

    Article  Google Scholar 

  • Joannopoulos JD, Johnson SG, Winn JN, Meade RD (2008) Molding the flow of light. Princeton University Press, Princeton

  • John S (1987) Strong localization of photons in certain disordered dielectric superlattices. Phys Rev Lett 58(23):2486

    Article  Google Scholar 

  • Kok AA, van der Tol JJ, Baets R, Smit MK (2009) Reduction of propagation loss in pillar-based photonic crystal waveguides. J Lightwave Technol 27(17):3904–3911

    Article  Google Scholar 

  • Krupa V, Triveni CL (2020) Design of biosensor for the detection of pregnancy based on hcg presence in urine using photonic crystal waveguide. In: 2020 IEEE international conference on electronics, computing and communication technologies (CONECCT) (pp 1–4). IEEE

  • Kulkarni S, Khan N, Sharan P, Ranjith B (2020) Bacterial analysis of drinking water using photonic crystal based optical sensor. In: 2020 7th international conference on computing for sustainable global development (INDIACom) (pp 186–191). IEEE

  • Kumar H, Vaibav AM, Srikanth PC (2020) 2D photonic crystal based biosensor for detection of cervical cancer cell. In: 2020 IEEE international conference on electronics, computing and communication technologies (CONECCT) (pp 1–4). IEEE

  • Kumar N, Suthar B (2019) Advances in photonic crystals and devices. CRC Press

    Book  Google Scholar 

  • Kurt H, Citrin DS (2005) New approaches in biochemical sensing using photonic crystals in the terahertz region. In: 2005 Joint 30th international conference on infrared and millimeter waves and 13th international conference on terahertz electronics (vol 1, pp 36–37). IEEE

  • Luff BJ, Harris RD, Wilkinson JS, Wilson R, Schiffrin DJ (1996) Integrated-optical directional coupler biosensor. Opt Lett 21(8):618–620

    Article  Google Scholar 

  • Nair RV, Vijaya R (2010) Photonic crystal sensors: an overview. Prog Quantum Electron 34(3):89–134

    Article  Google Scholar 

  • Naresh V, Lee N (2021) A review on biosensors and recent development of nanostructured materials-enabled biosensors. Sensors 21(4):1109

    Article  Google Scholar 

  • Nischita R, Gudagunti FD, Sharan P, Srinivas T (2015) 2-D photonic crystal based bio-chip for DNA analysis of breast cancer. In: 2015 International conference on pervasive computing (ICPC) (pp 1–4). IEEE

  • Olyaee S, Mohebzadeh-Bahabady A (2014) Two-curve-shaped biosensor using photonic crystal nano-ring resonators. J Nanostruct 4(3):303–308

    Google Scholar 

  • Painam B, Kaler RS, Kumar M (2017) Photonic crystal waveguide biochemical sensor for the approximation of chemical components concentrations. Plasmonics 12(3):899–904

    Article  Google Scholar 

  • Painam B, Teotia P, Kaler RS, Kumar M (2014) Bio-chemical sensor based on photonic crystal waveguide for estimation of sulphuric acid concentration. In: International conference on fibre optics and photonics (pp S5A–48). Optical Society of America.

  • Painam B, Kaler RS, Kumar M (2016) Active layer identification of photonic crystal waveguide biosensor chip for the detection of Escherichia coli. Opt Eng 55(7):077105

    Article  Google Scholar 

  • Patil H, Ashwini M, Indumathi TS, Sharan P (2013) Design and analysis of photonic crystal based fluidic sensor. In: Fifth international conference on advances in recent technologies in communication and computing (ARTCom 2013) (pp 183–188). IET

  • Radhouene M, Balaji VR, Najjar M, Robinson S, Janyani V, Murugan M (2021) Rounded square ring resonator based add drop filter for WDM applications using two dimensional photonic crystals. Opt Quant Electron 53(5):1–24

    Article  Google Scholar 

  • Radhouene M, Chhipa MK, Najjar M, Robinson S, Suthar B (2017) Novel design of ring resonator based temperature sensor using photonics technology. Photon Sensors 7(4):311–316

    Article  Google Scholar 

  • Rajasekar R, Jayabarathan JK, Robinson S (2019) Nano-optical filter based on multicavity coupled photonic crystal ring resonator. Phys E: Low-Dimen Syst Nanostruct 114:113591

    Article  Google Scholar 

  • Rajasekar R, Robinson S (2018a) Nano-electric field sensor based on two dimensional photonic crystal resonator. Opt Mater 85:474–482

    Article  Google Scholar 

  • Rajasekar R, Robinson S (2018b) Trapezoid 2D photonic crystal nanoring resonator-based channel drop filter for WDM systems. Photon Netw Commun 36(2):230–245

    Article  Google Scholar 

  • Robinson S, Dhanlaksmi N (2017) Photonic crystal based biosensor for the detection of glucose concentration in urine. Photon Sensors 7(1):11–19

    Article  Google Scholar 

  • Robinson S, Nakkeeran R (2012a) Investigation on two dimensional photonic crystal resonant cavity based bandpass filter. Optik 123(5):451–457

    Article  Google Scholar 

  • Robinson S, Nakkeeran R (2012b) PC based optical salinity sensor for different temperatures. Photon Sensors 2(2):187–192

    Article  Google Scholar 

  • Salmanpour A, Mohammadnejad S, Bahrami A (2015) Photonic crystal logic gates: an overview. Opt Quant Electron 47(7):2249–2275

    Article  Google Scholar 

  • Sani MH, Ghanbari A, Saghaei H (2021) High-sensitivity biosensor for simultaneous detection of cancer and diabetes using photonic crystal microstructure. Opt Quant Electron. https://doi.org/10.21203/rs.3.rs-451630/v1

    Article  Google Scholar 

  • Sharma P, Sharan P (2014) An optical sensor for propagation analysis of Lymphocyte cell for cancer cell detection. In: 2014 IEEE global humanitarian technology conference-south asia satellite (GHTC-SAS) (pp 93–98). IEEE

  • Sharma P, Sharan P, Deshmukh P (2015) A photonic crystal sensor for analysis and detection of cancer cells. In: 2015 International conference on pervasive computing (ICPC) (pp 1–5). IEEE

  • Sharma P, Sharan P (2014a) Design of photonic crystal-based biosensor for detection of glucose concentration in urine. IEEE Sens J 15(2):1035–1042

    Article  Google Scholar 

  • Sharma P, Sharan P (2015) An analysis and design of photonic crystal-based biochip for detection of glycosuria. IEEE Sens J 15(10):5569–5575

    Article  Google Scholar 

  • Singh S, Kumar V, Dhanjal DS, Datta S, Prasad R, Singh J (2020) Biological biosensors for monitoring and diagnosis. In: Microbial biotechnology: basic research and applications (pp 317–335). Springer, Singapore

  • Suganya T, Robinson S (2017) 2D photonic crystal based biosensor using rhombic ring resonator for glucose monitoring. ICTACT Microelectron 3(1):349–353

    Article  Google Scholar 

  • Sundhar A, Valli R, Robinson S, Abinayaa A, SivaBharathy C (2019) Two dimensional photonic crystal based bio sensor for cancer cell detection. In: 2019 IEEE international conference on system, computation, automation and networking (ICSCAN) (pp 1–3). IEEE

  • Suzuki T, Yu PK (1999) Existence of photonic band gaps in two-dimensional metallodielectric photonic crystals. Electromagnetics 19(3):321–335. https://doi.org/10.1063/1.107868

    Article  Google Scholar 

  • Swain KP, Palai G (2016) Estimation of human-hemoglobin using honeycomb structure: an application of photonic crystal. Optik 127(6):3333–3336

    Article  Google Scholar 

  • Tameh TA, Isfahani BM, Granpayeh N, Javan AM (2011) Improving the performance of all-optical switching based on nonlinear photonic crystal microring resonators. AEU-Int J Electron Commun 65(4):281–287

    Article  Google Scholar 

  • Yablonovitch E (1987) Inhibited spontaneous emission in solid-state physics and electronics. Phys Rev Lett 58(20):2059

    Article  Google Scholar 

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Authors and Affiliations

  1. School of Electronics Engineering, Vellore Institute of Technology, Vandalur, Kelambakkam Road, Chennai, Tamil Nadu, 600 127, India

    D. Gowdhami & V. R. Balaji

  2. Department of Electronics and Communication Engineering, SRM Valliammai Engineering College, Kattankulathur, Tamil Nadu, 603203, India

    M. Murugan

  3. Department of Electronics and Communication Engineering, Mount Zion College of Engineering and Technology, Pudukkottai, Tamil Nadu, 622 507, India

    S. Robinson

  4. Centre for BSSE, Indian Institute of Science, Bengaluru, Karnataka, 560012, India

    Gopalkrishna Hegde

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  1. D. Gowdhami
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  2. V. R. Balaji
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  3. M. Murugan
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  4. S. Robinson
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  5. Gopalkrishna Hegde
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Correspondence to D. Gowdhami.

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Gowdhami, D., Balaji, V.R., Murugan, M. et al. Photonic crystal based biosensors: an overview. ISSS J Micro Smart Syst 11, 147–167 (2022). https://doi.org/10.1007/s41683-022-00092-x

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  • DOI: https://doi.org/10.1007/s41683-022-00092-x

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