Sommario
Il microbiota intestinale è un ecosistema eterogeneo che ospita la maggior parte delle specie batteriche nell’uomo, e l’attività fisica sembra essere un potenziale fattore esterno in grado di influenzarne la biodiversità, sia in termini qualitativi che quantitativi. Ad oggi non è ancora chiaro quali popolazioni microbiche subiscano variazioni e in che modo, e ulteriori ricerche serviranno per comprendere se queste modificazioni abbiano effettivamente un impatto sulla promozione della salute.
Bibliografia
Cerdá B, Pérez M, Pérez-Santiago JD et al. (2016) Gut microbiota modification: another piece in the puzzle of the benefits of physical exercise in health? Front Physiol 7:51
Sender R, Fuchs S, Milo R (2016) Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans. Cell 164(3):337–340
Gallè F, Valeriani F, Cattaruzza MS et al. (2019) Exploring the association between physical activity and gut microbiota composition: a review of current evidence. Ann Ig 31(6):582–589
Flint HJ, Scott KP, Louis P, Duncan SH (2012) The role of the gut microbiota in nutrition and health. Nature Rev Gastroenterol Hepatol 9(10):577–589
Remely M, Aumueller E, Jahn D et al. (2014) Microbiota and epigenetic regulation of inflammatory mediators in type 2 diabetes and obesity. Benef Microbes 5(1):33–43
Cryan JF, O’Mahony S (2011) The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterol Motil 23(3):187–192
Krisko TI, Nicholls HT, Bare CJ et al. (2020) Dissociation of adaptive thermogenesis from glucose homeostasis in microbiome-deficient mice. Cell Metab 31(3):592–604
Matsumoto M, Inoue R, Tsukahara T et al. (2008) Voluntary running exercise alters microbiota composition and increases n-butyrate concentration in the rat cecum. Biosci Biotechnol Biochem 72(2):572–576
Forsythe P, Bienenstock J, Kunze WA (2014) Vagal pathways for microbiome-brain-gut axis communication. Adv Exp Med Biol 817:115–133
Queipo-Ortuño MI, Seoane LM, Murri M et al. (2013) Gut microbiota composition in male rat models under different nutritional status and physical activity and its association with serum leptin and ghrelin levels. PLoS ONE 8(5):e65465
Evans CC, LePard KJ, Kwak JW et al. (2014) Exercise prevents weight gain and alters the gut microbiota in a mouse model of high fat diet-induced obesity. PLoS ONE 9(3):e92193
Campbell SC, Wisniewski PJ, Noji M et al. (2016) The effect of diet and exercise on intestinal integrity and microbial diversity in mice. PLoS ONE 11(3):1–17
Petriz BA, Castro AP, Almeida JA et al. (2014) Exercise induction of gut microbiota modifications in obese, non-obese and hypertensive rats. BMC Genomics 15:511
Kang SS, Jeraldo PR, Kurti A et al. (2014) Diet and exercise orthogonally alter the gut microbiome and reveal independent associations with anxiety and cognition. Mol Neurodegener 9:36
Bressa C, Bailén-Andrino M, Pérez-Santiago J et al. (2017) Differences in gut microbiota profile between women with active lifestyle and sedentary women. PLoS ONE 12(2):e0171352
Munukka E, Ahtiainen JP, Puigbó P et al. (2018) Six week endurance exercise alters gut metagenome that is not reflected in systemic metabolism in over-weight women. Front Microbiol 9:2323
Allen JM, Mailing LJ, Niemiro GM et al. (2018) Exercise alters gut microbiota composition and function in lean and obese humans. Med Sci Sports Exerc 50(4):747–757
Estaki M, Pither J, Baumeister P et al. (2016) Cardiorespiratory fitness as a predictor of intestinal microbial diversity and distinct metagenomic functions. FASEB J 30(1):1027–1035
Durk RP, Castillo E, Márquez-Magaña L et al. (2018) Gut microbiota composition is related to cardiorespiratory fitness in healthy young adults. Int J Sport Nutr Exerc Metab 29(3):249–253
Petersen LM, Bautista EJ, Nguyen H et al. (2017) Community characteristics of the gut microbiomes of competitive cyclists. Microbiome 5(1):98
Scheiman J, Luber JM, Chavkin TA et al. (2019) Meta-omics analysis of elite athletes identifies a performance-enhancing microbe that functions via lactate metabolism. Nat Med 25(7):1104–1109
Clarke SF, Murphy EF, O’Sullivan O et al. (2014) Exercise and associated dietary extremes impact on gut microbial diversity. Gut 63(12):1913–1920
Everard A, Belzer C, Geurts L et al. (2013) Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci USA 110:9066–9071
Leeming ER, Johnson AJ, Spector TD, Le Roy CI (2019) Effect of diet on the gut microbiota: rethinking intervention duration. Nutrients 11(12):2862
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Gli autori Vittoria Cella, Silvia Migliaccio e Antonio Paoli dichiarano di non avere conflitti di interesse.
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Cella, V., Migliaccio, S. & Paoli, A. Microbiota intestinale ed esercizio fisico: nuova possibile area di intervento?. L'Endocrinologo 21, 338–343 (2020). https://doi.org/10.1007/s40619-020-00777-1
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DOI: https://doi.org/10.1007/s40619-020-00777-1