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Flavivirus Pathogenesis in the Mosquito Transmission Vector

  • Virology (A Nicola, Section Editor)
  • Published:
Current Clinical Microbiology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We hope to provide an overview of flavivirus pathogenesis in the mosquito, including the mosquito immune response to infection.

Recent Findings

There has been a great deal of research in the past decade examining interactions of flaviviruses with mosquito proteins as well as the complex immune reaction to flavivirus infection. We also touch upon novel strategies to prevent mosquito infection with flaviviruses of human importance.

Summary

The mosquito is a crucial component of the flavivirus transmission cycle, and thus, it is vital to thoroughly examine flavivirus pathogenesis in the mosquito vector. There have been some important recent findings in this area yet further research is needed for a comprehensive picture of mosquito-human flavivirus transmission.

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Authors and Affiliations

  1. Department of Pathology, Microbiology & Immunology, University of South Carolina School of Medicine, Columbia, SC, USA

    Andrea Troupin & Tonya M. Colpitts

  2. Department of Tropical Medicine, Tulane University School of Public Health & Tropical Medicine, New Orleans, LA, USA

    Crystal Grippin & Tonya M. Colpitts

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  1. Andrea Troupin
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  2. Crystal Grippin
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  3. Tonya M. Colpitts
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Correspondence to Tonya M. Colpitts.

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This article is part of the Topical Collection on Virology

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Troupin, A., Grippin, C. & Colpitts, T.M. Flavivirus Pathogenesis in the Mosquito Transmission Vector. Curr Clin Micro Rpt 4, 115–123 (2017). https://doi.org/10.1007/s40588-017-0066-6

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