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Periodontal Medicine—New Diagnostic Opportunities

  • Systemic Diseases (M Bartold, section editor)
  • Published:
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Abstract

Purpose of Review

We examined the literature on periodontal medicine to determine how this field has influenced the diagnosis of periodontal diseases and the search for biomarkers in oral fluids.

Recent Findings

Periodontal medicine has pushed the boundaries of biomarker discovery in oral fluids, where several analytes present in serum can be detected and potentially explored for the diagnosis of systemic conditions. The study of mechanisms linking oral and systemic diseases has also contributed to advances in our understanding of systemic modulation of the subgingival microenvironment and its effects on gingival crevicular fluid components and the local microbiota.

Summary

Recent technological advances in “omics” platforms allow us to examine concomitantly functional changes that occur in the host and the resident microbiota during disease processes. Integration of multi-omics data such as the one proposed by the Integrative Human Microbiome Project will afford new insights into the interplay between oral and systemic diseases.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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  1. Department of Periodontology, UNC School of Dentistry, Koury Health Sciences Building, 385 S. Columbia Street, Room 3506, Chapel Hill, NC, 27599-7455, USA

    Ricardo Teles

  2. Department of Applied Oral Sciences, Forsyth Institute, Cambridge, MA, USA

    Ricardo Teles

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Teles, R. Periodontal Medicine—New Diagnostic Opportunities. Curr Oral Health Rep 4, 158–166 (2017). https://doi.org/10.1007/s40496-017-0138-y

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