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The Potential Impact of Essential Nutrients Vitamins C and D upon Periodontal Disease Pathogenesis and Therapeutic Outcomes

  • Epidemiology (M Laine, Section Editor)
  • Published:
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Abstract

Diet has powerful effects upon inflammatory status, arguably as strong or stronger than microbial plaque. Despite a relationship between diet and periodontal inflammatory markers being established over 30 years ago, it is only recently that the mechanisms underpinning these effects have begun to be examined in detail. Following an analysis of the evidence base in 2011, this review focuses upon the most contemporaneous evidence relating specifically to the micronutrient vitamins C and D and their potential impact upon periodontal disease pathogenesis and/or therapeutic outcomes. The authors bring together both epidemiological and laboratory data and aim to outline avenues for potential studies given the limited number of larger well-conducted clinical interventional trials completed to date.

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Authors and Affiliations

  1. Division of Dentistry, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, J R Moore Building, Oxford Road, Manchester, M13 9PL, UK

    Gareth R Brock

  2. School of Dentistry, Institute of Clinical Sciences, College of Medical & Dental Sciences, The University of irmingham, Birmingham Dental School and Hospital, 5 Mill Pool Way, Birmingham, B5 7EG, UK

    Iain L C Chapple

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  1. Gareth R Brock
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Correspondence to Gareth R Brock.

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Iain L. C. Chapple reports grants from NSA LLC outside of the submitted work.

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Brock, G.R., Chapple, I.L.C. The Potential Impact of Essential Nutrients Vitamins C and D upon Periodontal Disease Pathogenesis and Therapeutic Outcomes. Curr Oral Health Rep 3, 337–346 (2016). https://doi.org/10.1007/s40496-016-0116-9

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