Abstract
Introduction
Expert judgement has a role in model-based economic evaluations (EEs) of healthcare interventions. This study aimed to produce reporting criteria for two types of study design to use expert judgement in model-based EE: (i) an expert elicitation (quantitative) study; and (ii) a Delphi study to collate (qualitative) expert opinion.
Methods
A two-round online Delphi process identified the degree of consensus for four core definitions (expert; expert parameter values; expert elicitation study; expert opinion) and two sets of reporting criteria in a purposive sample of experts. The initial set of reporting criteria comprised 17 statements for reporting a study to elicit parameter values and/or distributions and 11 statements for reporting a Delphi survey to obtain expert opinion. Fifty experts were invited to become members of the Delphi process panel by e-mail. Data analysis summarised the extent of agreement (using a pre-defined 75 % ‘consensus’ threshold) on the definitions and suggested reporting criteria. Free-text comments were analysed using thematic analysis.
Results
The final panel comprised 12 experts. Consensus was achieved for the definitions of expert (88 %); expert parameter values (83 %); and expert elicitation study (83 %). The panel recommended criteria to use when reporting an expert elicitation study (16 criteria) and a Delphi study to collate expert opinion (11 criteria).
Conclusion
This study has produced guidelines for reporting two types of study design to use expert judgement in model-based EE: (i) an expert elicitation study requiring 16 reporting criteria; and (ii) a Delphi study to collate expert opinion requiring 11 reporting criteria.
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Acknowledgments
CPI contributed to the design and the conduct of the study, commented on drafts of the manuscript and produced the final version of the manuscript. AT contributed to the design and the conduct of the study, analysed the data, commented on drafts of the manuscript and approved the final version of the manuscript. WR contributed to the design and the conduct of the study, commented on drafts of the manuscript and approved the final version of the manuscript. KP conceived the idea for this study, contributed to the design and the conduct of the study, produced a first draft of the manuscript, commented on subsequent drafts and approved the final version of the manuscript. We also want to thank the following members of the Health Economics Elicitation Group for their contribution to this study: Laura Bojke, Qi Cao, Ali Daneshkhah, Christopher Evans, Bogdan Grigore, Anthony O’Hagan, Vincent Levy, Claire Rothery, Fabrizio Ruggeri, Ken Stein, Matt Stevenson and Patricia Vella Bonanno.
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No funding was received for this study and the authors of this paper, Cynthia P. Iglesias, Alexander Thompson, Wolf H. Rogowski and Katherine Payne, declare that there is no conflict of interest regarding its publication.
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Iglesias, C.P., Thompson, A., Rogowski, W.H. et al. Reporting Guidelines for the Use of Expert Judgement in Model-Based Economic Evaluations. PharmacoEconomics 34, 1161–1172 (2016). https://doi.org/10.1007/s40273-016-0425-9
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DOI: https://doi.org/10.1007/s40273-016-0425-9