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Synthesis and biological evaluation of novel saccharin derivatives containing 1,2,3-triazole moiety

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Abstract

A series of novel saccharin derivatives containing 1,2,3-triazole moiety was synthesized in satisfactory yields. The structures of all the compounds were elucidated and confirmed by Fourier transform infrared(FTIR) spectroscopy, 1H and 13C nuclear magnetic resonance(1H NMR, 13C NMR) spectroscopy, and high resolution mass spectrometry(HRMS). The bioassays indicated that most of the title compounds displayed some extent herbicidal activities at 100 μg/mL.

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Authors and Affiliations

  1. College of Biotechnology, Tianjin University of Science and Technology, Tianjin, 300457, P. R. China

    Xiaobin Tang, Zhenghui Li & Peng Yu

  2. College of Sciences, Tianjin University of Science and Technology, Tianjin, 300457, P. R. China

    Wei Liu

  3. State Key Laboratory of Element Organic Chemistry, Institute of Element Organic Chemistry, Tianjin, 300071, P. R. China

    Yonghong Li

  4. College of Pharmacy, Nankai University, Tianjin, 300071, P. R. China

    Yu Guo & Cheng Yang

  5. High Throughput Molecular Drug Discovery Center, Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin, 300457, P. R. China

    Xiaobin Tang, Zhenghui Li, Lixin Li & Cheng Yang

Authors
  1. Xiaobin Tang
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  2. Zhenghui Li
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  3. Yonghong Li
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  4. Wei Liu
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  5. Peng Yu
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  6. Lixin Li
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  7. Yu Guo
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  8. Cheng Yang
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Corresponding author

Correspondence to Wei Liu.

Additional information

Supported by the National Natural Science Foundation of China(No.21302139).

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Tang, X., Li, Z., Li, Y. et al. Synthesis and biological evaluation of novel saccharin derivatives containing 1,2,3-triazole moiety. Chem. Res. Chin. Univ. 31, 71–77 (2015). https://doi.org/10.1007/s40242-015-4309-x

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  • DOI: https://doi.org/10.1007/s40242-015-4309-x

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