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Intermittent pneumatic compression combined with rehabilitation training improves motor function deficits in patients with acute cerebral infarction

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Abstract

To investigate the effect of intermittent pneumatic compression (IPC) combined with rehabilitation training on patients with acute cerebral infarction and motor impairment, seventy-four patients with acute cerebral infarction and hemiplegia were randomly and equally divided into two groups, the control group and the IPC treatment group. The patients in the control group received conventional drug therapy and rehabilitation training, and the patients in the treatment group received the IPC treatment in addition to the treatment given in the control group. Motor function, the primary outcome, of the two groups was evaluated by Fugl–Meyer motor function scores. The Barthel index assessment scale was used to evaluate the ability to perform activities of daily living of the two groups, as a secondary outcome. All these indicators were collected and compared before treatment and at 7 days, 14 days, and 30 days after treatment. The incidence of adverse reactions associated with treatment was also recorded. At 7, 14, and 30 days after treatment, the Fugl–Meyer scores (27.16 ± 7.37, 33.41 ± 7.16 and 38.72 ± 7.65) and Barthel scores (47.16 ± 7.37, 52.41 ± 7.16, and 56.09 ± 8.32) of the treatment group were also significantly higher than those (23.65 ± 3.11, 26.13 ± 3.25, and 28.75 ± 5.92; 44.15 ± 3.11, 46.63 ± 3.25 and 47.75 ± 4.22) of the control group (all P < 0.05). With the extension of follow-up time, both scores were higher. There were no treatment-related adverse events in either of the two groups of patients during or after treatment. In conclusion, the IPC combined with rehabilitation training can effectively improve motor function deficits, the ability to perform activities of daily living, and quality of life for patients.

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Author notes

  1. Jiangshan Wei and Xiangyu Zhu authors have contributed equally to this work.

Authors and Affiliations

  1. Department of Neurology, Hongze Huai’an District People’s Hospital, No.1 Huanghe West Road, Huai’an, 223300, Jiangsu, People’s Republic of China

    Jiangshan Wei

  2. Department of Neurology, Huai’an First People’s Hospital, the Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, Huai’an, 223300, Jiangsu, China

    Lei Xia & Qiu Han

  3. Department of Neurology, The Second People’s Hospital of Huai’an, The Affiliated Huai’an Hospital of Xuzhou Medical University, Huai’an, 223002, Jiangsu, China

    Ying Zhao, Guang Yang & Jun Shen

  4. ICU, The Second People’s Hospital of Huai’an, The Affiliated Huai’an Hospital of Xuzhou Medical University, No.62 Huaihai South Road, Huai’an, 223002, Jiangsu, People’s Republic of China

    Xiangyu Zhu

Authors
  1. Jiangshan Wei
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  2. Xiangyu Zhu
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  3. Lei Xia
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  4. Ying Zhao
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  7. Jun Shen
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Corresponding authors

Correspondence to Qiu Han or Jun Shen.

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Funding

This work was supported by the scientific research start-up funding project of the Affiliated Huai’an No.1 People’s Hospital of Nanjing Medical University, China (No. YGRS202005).

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The authors declare that they had no competing interests.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Wei, J., Zhu, X., Xia, L. et al. Intermittent pneumatic compression combined with rehabilitation training improves motor function deficits in patients with acute cerebral infarction. Acta Neurol Belg 121, 1561–1566 (2021). https://doi.org/10.1007/s13760-020-01414-2

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  • DOI: https://doi.org/10.1007/s13760-020-01414-2

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