Abstract
The results revealed that different fractions of Commelina diffusa Burm. f. produced significant (p < 0.001, p < 0.01, p < 0.05, p < 0.02 and p < 0.5) inhibitory activity against the test bacteria and fungi. Methanolic fraction produced the highest zone of inhibition against the test bacteria (11 to 19 mm) which was followed by diethyl etheric extract (3 to 9 mm) and petroleum etheric extract (1 to 2 mm). Again, the methanolic extract showed the highest activity (the lowest MICs; 15.62 to 62.5 μg/μl) against seven species among the 11. In case of diethyl etheric and petroleum etheric fractions MICs were found to be (15.62 to 125 μg/μl) and (31.25 to 500 μg/μl), respectively. The diethyl etheric fraction showed the highest zone of inhibition against the fungi (15 to 19 mm) which was followed by methanolic extract (12 to 19 mm) and petroleum etheric extract (1 to 9 mm). Against the fungi the diethyl etheric extract showed the highest activity (i.e. the lowest MICs; 15.62 to 31.25 μg/μl). In case of methanolic and petroleum etheric fractions minimum inhibitory concentrations were found to be (15.62 to 125 μg/μl) and (31.25 to 250 μg/μl), respectively.
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Acknowledgement
Sincere thanks for the cooperation to the Head, Department of Microbiology, University of Chittagong, Bangladesh for providing the test organisms to carry out the research work and Mr. Mhammed Mohiuddin for taxonomic identification of the sample.
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Khan, M.A.A., Islam, M.T. & Sadhu, S.K. Evaluation of phytochemical and antimicrobial properties of Commelina diffusa Burm. f.. Orient Pharm Exp Med 11, 235–241 (2011). https://doi.org/10.1007/s13596-011-0028-0
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DOI: https://doi.org/10.1007/s13596-011-0028-0