Skip to main content

Advertisement

Log in

Single-port laparoscopic appendectomy using new surgical procedure versus conventional three-port laparoscopic appendectomy

  • Original Article
  • Published:
Updates in Surgery Aims and scope Submit manuscript

Abstract

The aim of this study was to compare the clinic outcomes between new single-port laparoscopic appendectomy (NSLA) and conventional three-port laparoscopic appendectomy (CTLA) for patients with acute appendicitis. Patients who were diagnosed with acute appendicitis and underwent appendectomy were retrospectively collected from a single clinical center from September 2021 to June 2023. Baseline characteristics, surgical information, and postoperative information were compared between the NSLA group and the CTLA group. Univariate and multivariate logistic regression analyses were used to find out the predictors of overall complications. A total of 296 patients were enrolled from a single clinical medical center. There were 146 (49.3%) males and 150 (50.7%) females. There were 54 (18.2%) patients in the NSLA group and 242 (81.8%) patients in the CTLA group. After data analysis, we found the patients in the NSLA group had a shorter postoperative hospital stay (P < 0.01) than the CTLA group. The other outcomes including intraoperative blood loss (P = 0.167), operation time (P = 0.282), nature of the appendix (P = 0.971), and overall complications (P = 0.543) were not statistically different. After univariate and multivariate logistic regression analysis, we found that age (P = 0.018, OR = 1.039, 95% CI = 1.007–1.072), neutrophil percentage (P = 0.018, OR = 1.070, 95% CI = 1.011–1.132), and fever (P = 0.019, OR = 6.112, 95% CI = 1.340–27.886) were the predictors of overall complications. However, the surgical procedure (NSLA versus CTLA) was not a predictor of overall complications (P = 0.376, OR = 1.964, 95% CI = 0.440–8.768). Compared with CTLA, there was no significant increase in postoperative overall complications with NSLA, making it a safe and feasible new surgical procedure. More studies are needed to evaluate the long-term results.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Data availability

The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.

References

  1. Ferris M, Quan S, Kaplan BS, Molodecky N, Ball CG, Chernoff GW et al (2017) The global incidence of appendicitis: a systematic review of population-based studies. Ann Surg 266(2):237–241. https://doi.org/10.1097/SLA.0000000000002188

    Article  PubMed  Google Scholar 

  2. Di Saverio S, Podda M, De Simone B, Ceresoli M, Augustin G, Gori A et al (2020) Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines. World J Emerg Surg 15(1):27. https://doi.org/10.1186/s13017-020-00306-3

    Article  PubMed  PubMed Central  Google Scholar 

  3. Wu J, Li M, Liu Q, Xu X, Lu X, Ma G et al (2021) Current practice of acute appendicitis diagnosis and management in China (PANDA-C): a national cross-sectional survey. Surg Infect 22(9):973–982. https://doi.org/10.1089/sur.2021.061

    Article  Google Scholar 

  4. O’Leary DP, Walsh SM, Bolger J, Baban C, Humphreys H, O’Grady S et al (2021) A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis: results of the COMMA trial. Ann Surg 274(2):240–247. https://doi.org/10.1097/SLA.0000000000004785

    Article  PubMed  Google Scholar 

  5. Semm K (1983) Endoscopic appendectomy. Endoscopy 15(2):59–64. https://doi.org/10.1055/s-2007-1021466

    Article  CAS  PubMed  Google Scholar 

  6. Towfigh S, Chen F, Mason R, Katkhouda N, Chan L, Berne T (2006) Laparoscopic appendectomy significantly reduces length of stay for perforated appendicitis. Surg Endosc 20(3):495–499. https://doi.org/10.1007/s00464-005-0249-8

    Article  CAS  PubMed  Google Scholar 

  7. Golub R, Siddiqui F, Pohl D (1998) Laparoscopic versus open appendectomy: a metaanalysis. J Am Coll Surg 186(5):545–553. https://doi.org/10.1016/s1072-7515(98)00080-5

    Article  CAS  PubMed  Google Scholar 

  8. Giday SA, Kantsevoy SV, Kalloo AN (2006) Principle and history of natural orifice translumenal endoscopic surgery (NOTES). Minim Invasive Ther Allied Technol 15(6):373–377. https://doi.org/10.1080/13645700601038010

    Article  PubMed  Google Scholar 

  9. Buess GF (2008) Natural orifice transluminal endoscopic surgery (NOTES). Minim Invasive Ther Allied Technol 17(6):329–330. https://doi.org/10.1080/13645700802528082

    Article  PubMed  Google Scholar 

  10. Arezzo A, Repici A, Kirschniak A, Schurr MO, Ho CN, Morino M (2008) New developments for endoscopic hollow organ closure in prospective of NOTES. Minim Invasive Ther Allied Technol 17(6):355–360. https://doi.org/10.1080/13645700802538628

    Article  PubMed  Google Scholar 

  11. Chow A, Purkayastha S, Aziz O, Paraskeva P (2010) Single-incision laparoscopic surgery for cholecystectomy: an evolving technique. Surg Endosc 24(3):709–714. https://doi.org/10.1007/s00464-009-0655-4

    Article  PubMed  Google Scholar 

  12. Poon JT, Cheung CW, Fan JK, Lo OS, Law WL (2012) Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial. Surg Endosc 26(10):2729–2734. https://doi.org/10.1007/s00464-012-2262-z

    Article  PubMed  Google Scholar 

  13. Jeong BC, Park YH, Han DH, Kim HH (2009) Laparoendoscopic single-site and conventional laparoscopic adrenalectomy: a matched case-control study. J Endourol 23(12):1957–1960. https://doi.org/10.1089/end.2009.0404

    Article  PubMed  Google Scholar 

  14. Page AJ, Pollock JD, Perez S, Davis SS, Lin E, Sweeney JF (2010) Laparoscopic versus open appendectomy: an analysis of outcomes in 17,199 patients using ACS/NSQIP. J Gastrointest Surg 14(12):1955–1962. https://doi.org/10.1007/s11605-010-1300-1

    Article  PubMed  Google Scholar 

  15. Clavien PA, Barkun J, de Oliveira ML, Vauthey JN, Dindo D, Schulick RD et al (2009) The Clavien-Dindo classification of surgical complications: five-year experience. Ann Surg 250(2):187–196. https://doi.org/10.1097/SLA.0b013e3181b13ca2

    Article  PubMed  Google Scholar 

  16. Chen Y, Guo S, Liu Y, Yuan J, Fan Z (2022) Single-port laparoscopic appendectomy using a needle-type grasping forceps compared with conventional three-port laparoscopic appendectomy for patients with acute uncomplicated appendicitis: a single-center retrospective study. J Int Med Res 50(8):3000605221119647. https://doi.org/10.1177/03000605221119647

    Article  CAS  PubMed  Google Scholar 

  17. Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A et al (2019) Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children: a systematic review and meta-analysis. Ann Surg 270(6):1028–1040. https://doi.org/10.1097/SLA.0000000000003225

    Article  PubMed  Google Scholar 

  18. Minneci PC, Hade EM, Metzger GA, Saito JM, Mak GZ, Deans KJ, Midwest Pediatric Surgery Consortium (2021) Association of initial treatment with antibiotics vs surgery with treatment success and disability in subgroups of children with uncomplicated appendicitis. JAMA 325(24):2502–2504. https://doi.org/10.1001/jama.2021.6710

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Moris D, Paulson EK, Pappas TN (2021) Diagnosis and management of acute appendicitis in adults: a review. JAMA 326(22):2299–2311. https://doi.org/10.1001/jama.2021.20502

    Article  PubMed  Google Scholar 

  20. Salminen P, Tuominen R, Paajanen H, Rautio T, Nordström P, Aarnio M et al (2018) Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 320(12):1259–1265. https://doi.org/10.1001/jama.2018.13201. (Erratum in: JAMA. 2018;320(16):1711)

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Talan DA, Di Saverio S (2021) Treatment of acute uncomplicated appendicitis. N Engl J Med 385(12):1116–1123. https://doi.org/10.1056/NEJMcp2107675

    Article  PubMed  Google Scholar 

  22. Köhler F, Hendricks A, Kastner C, Müller S, Boerner K, Wagner JC et al (2021) Laparoscopic appendectomy versus antibiotic treatment for acute appendicitis-a systematic review. Int J Colorectal Dis 36(10):2283–2286. https://doi.org/10.1007/s00384-021-03927-5

    Article  PubMed  PubMed Central  Google Scholar 

  23. Khan MN, Fayyad T, Cecil TD, Moran BJ (2007) Laparoscopic versus open appendectomy: the risk of postoperative infectious complications. JSLS 11(3):363–367

    PubMed  PubMed Central  Google Scholar 

  24. Vettoretto N, Agresta F (2011) A brief review of laparoscopic appendectomy: the issues and the evidence. Tech Coloproctol 15(1):1–6. https://doi.org/10.1007/s10151-010-0656-2

    Article  CAS  PubMed  Google Scholar 

  25. Qiu J, Yuan H, Chen S, He Z, Wu H (2014) Single-port laparoscopic appendectomy versus conventional laparoscopic appendectomy: evidence from randomized controlled trials and nonrandomized comparative studies. Surg Laparosc Endosc Percutan Tech 24(1):12–21. https://doi.org/10.1097/SLE.0b013e3182937da4

    Article  PubMed  Google Scholar 

  26. Lee WS, Choi ST, Lee JN, Kim KK, Park YH, Lee WK et al (2013) Single-port laparoscopic appendectomy versus conventional laparoscopic appendectomy: a prospective randomized controlled study. Ann Surg 257(2):214–218. https://doi.org/10.1097/SLA.0b013e318273bde4

    Article  PubMed  Google Scholar 

  27. Teoh AY, Chiu PW, Wong TC, Wong SK, Lai PB, Ng EK (2011) A case-controlled comparison of single-site access versus conventional three-port laparoscopic appendectomy. Surg Endosc 25(5):1415–1419. https://doi.org/10.1007/s00464-010-1406-2

    Article  PubMed  Google Scholar 

  28. Esparaz JR, Jeziorczak PM, Mowrer AR, Chakraborty SR, Nierstedt RT, Zumpf KB et al (2019) Adopting single-incision laparoscopic appendectomy in children: is it safe during the learning curve? J Laparoendosc Adv Surg Tech A 29(10):1306–1310. https://doi.org/10.1089/lap.2019.0112

    Article  PubMed  Google Scholar 

  29. Assali S, Eapen S, Carman T, Horattas S, Daigle CR, Paranjape C (2018) Single-port laparoscopic appendectomy: beyond the learning curve: a retrospective comparison with multi-port laparoscopic appendectomy. Surg Laparosc Endosc Percutan Tech 28(5):291–294. https://doi.org/10.1097/SLE.0000000000000546

    Article  PubMed  Google Scholar 

  30. Kang BM, Choi SI, Kim BS, Lee SH (2018) Single-port laparoscopic surgery in uncomplicated acute appendicitis: a randomized controlled trial. Surg Endosc 32(7):3131–3137. https://doi.org/10.1007/s00464-018-6028-0

    Article  PubMed  Google Scholar 

  31. Kim Y, Lee W (2016) The learning curve of single-port laparoscopic appendectomy performed by emergent operation. World J Emerg Surg 5(11):39. https://doi.org/10.1186/s13017-016-0096-z

    Article  Google Scholar 

  32. Isik A, Demiryilmaz I, Yilmaz I et al (2016) Effectiveness of manual knotting at laparoscopic appendectomy. Gazi Med J 27:19–20

    Google Scholar 

Download references

Acknowledgements

The authors are grateful to all the colleagues who helped in the preparation of this article.

Author information

Authors and Affiliations

Authors

Contributions

Data extraction, FL and Z-WL; quality assessments, DP, WZ, and C-YW; data analysis, X-RL, Z-WL, and QL; writing the main manuscript text, FL; writing—review and editing, X-RL, Z-WL, X-YL, X-PS, L-SL, YT, and QL. DP prepared Figs. 1, 2, 3. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Dong Peng.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethics approval and informed consent

The study was approved by the ethics committee of our institution (The First Affiliated Hospital of Chongqing Medical University, K2023-339). This study was conducted in accordance with the World Medical Association Declaration of Helsinki as well.

Consent for publication

Not applicable.

Research involving human participants and/or animals

Not applicable.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, F., Lv, Q., Wang, CY. et al. Single-port laparoscopic appendectomy using new surgical procedure versus conventional three-port laparoscopic appendectomy. Updates Surg (2024). https://doi.org/10.1007/s13304-024-01775-w

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s13304-024-01775-w

Keywords

Navigation