Abstract
Burns cause a loss of skin barrier function, rendering it prone to infection. The prevention of infection comprises a focus on the treatment of patients with burns. Therefore, we analysed the results of microbiological tests of patients with severe and extremely severe burns to provide a basis for the prevention and treatment of infection in patients with burns. The results of microbiological tests of patients with severe and extremely severe burns admitted to our burn centre between 2009 and 2019 were retrospectively reviewed. The overall positive rate of microbial detection was 40.67% and did not significantly decline over the 10-year study period. The most common positive sites were wounds, sputum, and urine. The most common bacterial species causing the infections were Acinetobacter baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa. Furthermore, the predictors of a positive detection, overall and at various sites, mainly included the burn area and depth, inhalation injury, and length of the hospital stay. Positive detection was an important predictor of the prognosis. In particular, a positive blood culture and Klebsiella pneumoniae had better predictive strength for mortality than other sites and strains. This study analysed the microbiological testing results at a single burn centre over a period of 10 years. The results provide information regarding the predictors of a positive detection and the influence of a positive detection on prognosis, and can be used as a basis for the development of clinical infection prevention and treatment strategies, as well as the selection of treatment measures.
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Abbreviations
- TBSA:
-
Total body surface area
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Acknowledgements
The authors thank all the doctors of the burn department of the First Affiliated Hospital of Naval Medical University and acknowledge their immense dedication in providing the first line of clinical care and treatment of a vast number of patients with major burns.
Funding
This research was supported by the Hangzhou Medical and Health Science and Technology project (Grant/award number: B20200432), the National Natural Science Foundation of China Youth Award (Grant/award number: 81401596), and the National Natural Science Foundation of China (Grant/award number: 81772125 and 81701899).
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Jian, J., Yu, P., Zheng-Li, C. et al. Epidemiological retrospective analysis in major burn patients: single centre medical records from 2009 to 2019. Updates Surg 74, 1453–1459 (2022). https://doi.org/10.1007/s13304-021-01215-z
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DOI: https://doi.org/10.1007/s13304-021-01215-z