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Diagnosis of Seronegative Rheumatoid Arthritis by 68 Ga-FAPI PET/CT

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Abstract

Early diagnosis of rheumatoid arthritis with the initiation of disease-modifying antirheumatic drugs is important to prevent future disability. Seronegative rheumatoid arthritis lacks the classical immunological markers, thus imposing clinical diagnostic difficulty. In this case, we reported 68 Ga-FAPI PET/CT findings of seronegative rheumatoid arthritis in a 60-year-old lady. This case illustrates how 68 Ga-FAPI PET/CT aids in the diagnosis of seronegative rheumatoid arthritis.

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Authors and Affiliations

  1. Department of Nuclear Medicine & PET, Hong Kong Sanatorium & Hospital, 2 Village Road, Happy Valley, Hong Kong, China

    Shing Kee Cheung, Sirong Chen, Yuet Hung Wong, Kwan Kit Wu & Chi Lai Ho

  2. Research Department, Hong Kong Sanatorium & Hospital, Hong Kong, China

    Sirong Chen

Authors
  1. Shing Kee Cheung
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  2. Sirong Chen
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  3. Yuet Hung Wong
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  4. Kwan Kit Wu
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  5. Chi Lai Ho
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Contributions

Shing Kee Cheung: data interpretation, acquiring data, drafting the manuscript, approving the final content of the manuscript. Sirong Chen: analyzing data, revising the manuscript, approving the final content of the manuscript. Yuet Hung Wong: data interpretation, approving the final content of the manuscript. Kwan Kit Wu: data interpretation, approving the final content of the manuscript. Chi Lai Ho: conception, critically revising the manuscript, approving the final content of the manuscript.

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Correspondence to Chi Lai Ho.

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Conflict of Interest

Shing Kee Cheung, Sirong Chen, Yuet Hung Wong, Kwan Kit Wu, and Chi Lai Ho declare no conflict of interest.

Ethical Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Written and informed consent was obtained from the patient.

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Cheung, S.K., Chen, S., Wong, Y.H. et al. Diagnosis of Seronegative Rheumatoid Arthritis by 68 Ga-FAPI PET/CT. Nucl Med Mol Imaging 57, 44–45 (2023). https://doi.org/10.1007/s13139-022-00779-x

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  • DOI: https://doi.org/10.1007/s13139-022-00779-x

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