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Intramastoid Phosphaturic Mesenchymal Tumor Causing Hypophosphatemic Osteomalacia Detected on 68Ga-DOTATATE PET/CT But Not on 99mTc-Sestamibi and 18F-FDG Scans

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Abstract

68Ga-DOTATATE uptake in mesenchymal tumors causing hypophosphatemic osteomalacia has been recently described. Herein, we present a case of 68Ga-DOTATATE uptake in an intramastoid phosphaturic mesenchymal tumor that had not been depicted in previous 99mTc-Sestamibi and 18F-FDG scans. The lesion was surgically removed and the phosphorus level increased to the normal range.

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Acknowledgments

The authors are grateful to Drs. Vitor Gabriel Ribeiro Grossi and Eloiza Wilma Poma Gonzales for providing the histological images.

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Correspondence to Paulo Schiavom Duarte.

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Carlo Scognamiglio Renner Araujo, Luciana Parente Costa Seguro, Paulo Schiavom Duarte, Carlos Alberto Buchpiguel, and Rosa Maria Rodrigues Pereira declare that they have no conflict of interest.

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All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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The institutional review board of our institute approved this study, and the requirement to obtain informed consent was waived.

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Araujo, C.S.R., Seguro, L.P.C., Duarte, P.S. et al. Intramastoid Phosphaturic Mesenchymal Tumor Causing Hypophosphatemic Osteomalacia Detected on 68Ga-DOTATATE PET/CT But Not on 99mTc-Sestamibi and 18F-FDG Scans. Nucl Med Mol Imaging 53, 436–441 (2019). https://doi.org/10.1007/s13139-019-00616-8

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