Skip to main content
Log in

Fibrosing Mediastinitis: a Rare Cause of Unilateral Absent Lung Perfusion on a V/Q Scan

  • Interesting Image
  • Published:
Nuclear Medicine and Molecular Imaging Aims and scope Submit manuscript

Abstract

We report a case of a 29-year-old female with a history of asthma, post-partum ARDS, and pulmonary hypertension who presents with severe shortness of breath. The patient describes her shortness of breath as progressive over the past 10 years. Chest radiography and CT angiography of the thorax showed findings consistent with fibrosing mediastinitis with severe stenosis of the left main pulmonary artery. This resulted in appearance of unilateral absent left lung perfusion on quantitative Tc-99-MAA perfusion and Xe-133 ventilation (V/Q) scan.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR. Fibrosing mediastinitis. Radiographics. 2001;21:737–57.

    Article  CAS  PubMed  Google Scholar 

  2. Loyd JE, Tillman BF, Atkinson JB, Des Prez RM. Mediastinal fibrosis complicating histoplasmosis. Medicine (Baltimore). 1988;67:295–310.

    Article  CAS  Google Scholar 

  3. Sherrick AD, Brown LR, Harms GF, Myers JL. The radiographic findings of fibrosing mediastinitis. Chest. 1994;106:484–9.

    Article  CAS  PubMed  Google Scholar 

  4. Kandzari DE, Warner JJ, O’Laughlin MP, Harrison JK. Percutaneous stenting of right pulmonary artery stenosis in fibrosing mediastinitis. Catheter Cardiovasc Interv. 2000;49:321–4.

    Article  CAS  PubMed  Google Scholar 

  5. Oulmont N. Des oblitérations de la veine cave supérieure. Paris: J.B. Ballière; 1855.

    Google Scholar 

  6. Thiessen R, Matzinger F, Seely J, Aina R, MacLeod P. Fibrosing mediastinitis: successful stenting of the pulmonary artery. Can Respir J. 2008;15:41–4.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Gustafson MR, Moulton MJ. Fibrosing mediastinitis with severe bilateral pulmonary artery narrowing: RV–RPA bypass with a homograft conduit. Tex Heart Inst J. 2012;39:412–5.

    PubMed  PubMed Central  Google Scholar 

  8. Dunn EJ, Ulicny KS, Wright CB, Gottesman L. Surgical implications of sclerosing mediastinitis: a report of six cases and review of the literature. Chest. 1990;97:338–46.

    Article  CAS  PubMed  Google Scholar 

  9. Kadiev S, Daniels C, Sparks E, Hill S, Cheatham J, Diaz P. Histoplasmosis-induced fibrosing mediastinitis with severe right pulmonary artery stenosis successfully managed with cutting balloon angioplasty and endovascular stent placement. Chest. 2007;132:729A.

    Article  Google Scholar 

  10. Doyle TP, Loyd JE, Robbins IM. Percutaneous pulmonary artery and vein stenting. A novel treatment for mediastinal fibrosis. Am J Respir Crit Care Med. 2001;164:657–0.

    Article  CAS  PubMed  Google Scholar 

  11. Smith JS, et al. Pulmonary artery stenosis secondary to fibrosing mediastinitis: management with cutting balloon angioplasty and endovascular stenting. Vasc Endovasc Surg. 2011;45:170–3.

    Article  Google Scholar 

  12. Chow B, Wittram C, Lee VW. Unilateral absence of pulmonary perfusion mimicking pulmonary embolism. Am J Roentgenol. 2001;176(3):712.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Simin Dadpravarar.

Ethics declarations

Conflict of Interest

Alyssa Goldbach, Suzanne Pascarella, and Simin Dadpravar declare that they have no conflict of interest.

Ethical Statement

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Institutional review board of our institute approved this retrospective study, and the requirement to obtain informed consent was waived.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Goldbach, A.R., Pascarella, S. & Dadpravarar, S. Fibrosing Mediastinitis: a Rare Cause of Unilateral Absent Lung Perfusion on a V/Q Scan. Nucl Med Mol Imaging 52, 401–404 (2018). https://doi.org/10.1007/s13139-018-0545-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13139-018-0545-6

Keywords

Navigation