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Dopaminerge Modulation striataler Plastizität

Türöffnerfunktion in der Automatisierung von Willkürbewegungen

Dopaminergic modulation of striatal plasticity

Gateway to movement automatization

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Zusammenfassung

Der vorliegende Beitrag versucht, einen Überblick über die Neurobiologie der Automatisierung von Willkürbewegungen zu geben. Insbesondere wird aufgezeigt, dass eine zunehmende Bewegungsautomatisierung mit synaptischen Plastizitätsvorgängen im kortikokortikalen und kortikostriatalen System einhergeht, die vermutlich zu Veränderungen in den neuronalen Repräsentationen der geübten Bewegungen führen. Sodann wird die Rolle phasischer Dopaminaktivierungen und deren modulatorischer Effekt auf striatale Plastizitätsvorgänge bei denjenigen neuronalen Phänomenen diskutiert, die mit fortschreitendem Training beobachtet werden.

Abstract

This article attempts to outline the neuronal foundations of movement automatization. In particular, it is shown that an increase in automaticity corresponds to processes of synaptic plasticity in the corticostriatal and corticocortical system. This mechanism is supposed to induce changes in the neuronal representations of the respective skill. Furthermore, the role of phasic dopamine release will be discussed with respect to its modulating effect on processes of plasticity.

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  1. Fakultät für Sport- und Gesundheitswissenschaft, Technische Universität München, Georg-Brauchle-Ring 60/62, 80992, München, Deutschland

    Frieder Beck

  2. Sportwissenschaftliches Institut, Universität des Saarlandes, Saarbrücken, Deutschland

    Klaus Blischke

  3. Abteilung Psychiatrie III, Universitätsklinikum Ulm, Ulm, Deutschland

    Birgit Abler

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Beck, F., Blischke, K. & Abler, B. Dopaminerge Modulation striataler Plastizität. Sportwiss 42, 271–279 (2012). https://doi.org/10.1007/s12662-012-0230-3

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