Skip to main content

Advertisement

Log in

Treatment and control of Trixacarus caviae infestation in a conventional guinea pig (Cavia porcellus) breeding colony

  • Original Article
  • Published:
Journal of Parasitic Diseases Aims and scope Submit manuscript

Abstract

A case of sarcoptic mange caused by Trixacarus caviae in a conventional guinea pig breeding colony is reported. The infestation was reported in a large colony of guinea pigs during the month of July, 2013 affecting 30 breeder guinea pigs. Severely infested animals were treated individually with subcutaneous injection of ivermectin 1 % w/v (Neomec®) at the rate of 400 µg/kg body weight 10 days apart. Three doses of ivermectin were sufficient to eliminate the parasite which tested negative after 30 days of the first treatment. The entire colony was given preventive dose of ivermectin spray (2 mg/ml solution) following the same schedule. Strict hygienic measures were followed. New hair growth in the severely affected animals was evidenced on 30th day of treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  • Ackerman L (1987) Trixacarus caviae infestation in a guinea pig. Can Vet J 28:613

    CAS  PubMed  PubMed Central  Google Scholar 

  • Eshar D, Bdolah-Abram T (2012) Comparison of efficacy, safety, and convenience of selamectin versus ivermectin for treatment of Trixacarus caviae mange in pet guinea pigs (Cavia porcellus). J Am Vet Med Assoc 241(8):1056–1058. doi:10.2460/javma.241.8.1056

    Article  CAS  PubMed  Google Scholar 

  • FAO monograph 41-3, Residues of some veterinary drugs in foods and animals. Available at: ftp:ftp.//fao.org/ag/agn/jecfa/vetdrug/41-3-ivermectin.pdf or http://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-vetdrugs/en/

  • Fuentealba C, Hanna P (1996) Mange induced by Trixacarus caviae in a guinea pig. Can Vet J 37:749–750

    CAS  PubMed  PubMed Central  Google Scholar 

  • Harikrishnan VS, Ranaraj VR, Fernandez AC (2009) Incidence of Chirodiscoides caviae in laboratory rats-screening, identification and treatment. Scand J Lab Anim Sci 36(2):147–153

    CAS  Google Scholar 

  • Holt DC, Fischer K, Allen GE, Wilson D, Wilson P, Slade R, Currie BJ, Walton SF, Kemp DJ (2003) Mechanisms for a novel immune evasion strategy in the scabies mite Sarcoptes Scabiei: a multigene family of inactivated serine proteases. J Invest Dermatol 121(6):1419–1424

    Article  CAS  PubMed  Google Scholar 

  • Honda M, Namikawa K, Hirata H, Neo S, Marou T, Lynch J, Chida A, Morita T (2011) An outbreak of Trixacarus caviae infestation in guinea pigs at an animal petting facility and an evaluation of the safety and suitable dose of selamectin treatment. J Parasitol 97(4):731–734

    Article  CAS  PubMed  Google Scholar 

  • Izdebska JN, Rolbiecki L (2013) Sarcoptic mites (Acari, Sarcoptidae) parasitizing the brown rat Rattus norvegicus (Berkenhout 1769) (Rodentia, Muridae), with a new data for the fauna of Poland. Ann Parasitol 59(3):125–128

    PubMed  Google Scholar 

  • Kummel BA, Estes SA, Arlian LG (1980) Trixacarus caviae infestation of guinea pigs. J Am Vet Med Assoc 177:903–908

    CAS  PubMed  Google Scholar 

  • Mandigers PJ, van der Hage MH, Westerhof I, Dorrestein GM (1993) A field study of the efficacy of ivermectin in propylene glycol in the treatment of mange in guinea pigs [in Dutch]. Tijdschr Diergeneeskd 118:42–46

    CAS  PubMed  Google Scholar 

  • McKellar QA, Midgley DM, Galbraith EA, Scott EW, Bradley A (1992) Clinical and pharmacological properties of ivermectin in rabbits and guinea pigs. Vet Rec 130(4):71–73

    Article  CAS  PubMed  Google Scholar 

  • Méabed EMH (2013) Oral ivermectin as a therapeutic agent in patients with scabies. Rawal Med J 38:127–130

    Google Scholar 

  • Mederle N, Indre D (2009) Trixacarus caviae infestation in guinea pigs case report. Lucrări Ştiinłifice Med Vet XLII 1:101–104

    Google Scholar 

  • Mircean V, Titilincu A, Băgut T, Dumitrache M (2009) Research on the etiology of skin diseases in laboratory animals. Bull UASVM, Vet Med 66(2):112–118

    Google Scholar 

  • Singh SK, Dimri U, Ahmed QS, Sayedda K, Singh KV (2013) Efficacy of doramectin in Trixacarus caviae infestation in guinea pig (Cavia porcellus). J Parasit Dis 37(1):148–150. doi:10.1007/s12639-012-0155-7

    PubMed  Google Scholar 

  • Walton SF (2010) The immunology of susceptibility and resistance to scabies. Parasite Immunol 32:532–540. doi:10.1111/j.1365-3024.2010.01218.x

    CAS  PubMed  Google Scholar 

Download references

Acknowledgments

The author thankfully acknowledges the Director, Pasteur institute of India, Coonoor and Dr K N Venkataramana, Assistant director for providing infrastructure to carry out the work, Dr S Sahu for valuable inputs in correcting the manuscript, Mr N M Ramakrishnan and all the staff members of Laboratory Animal Division for their technical support, Dr S. Islam and Dr N N Barman, CVSc, Khanapara, Assam for their valuable guidance in diagnosis and treatment of the case.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Anjan Jyoti Nath.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nath, A.J. Treatment and control of Trixacarus caviae infestation in a conventional guinea pig (Cavia porcellus) breeding colony. J Parasit Dis 40, 1213–1216 (2016). https://doi.org/10.1007/s12639-015-0652-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12639-015-0652-6

Keywords

Navigation