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Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods

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Abstract

Toxoplasma gondii is a zoonotic obligatory intracellular protozoan parasite with the capability to infect all warm-blooded animals. One of the great concerns is that it can lead to ovine abortion in sheep growing industry. Different diagnostic methods such as serology, pathology, immunohistochemistry, bioassay and molecular detection have been used in order to detect ovine abortion associated with T. gondii. In this case, an outbreak of congenital toxoplasmosis based on serological, macroscopic, pathological detection and isolation of T. gondii by bioassay is described and emphasized on the importance of this route of transmission that caused lamb losses and an increase in possible sources of infection for human and environment.

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References

  • Blewett DA, Watson WA (1983) The epidemiology of ovine toxoplasmosis. II. Possible sources of infection in outbreaks of clinical disease. British Vet J 139:546–555

    CAS  Google Scholar 

  • Buxton D (1990) Ovine toxoplasmosis: a review. J Royal Soc Med 83:509–511

    CAS  Google Scholar 

  • Buxton D (1991) Toxoplasmosis. In: Martin WB, Aitken ID (eds) Diseases of sheep, 2nd edn. Blackwell Scientific Publications, Oxford, pp 49–58

    Google Scholar 

  • Buxton D (2008) Toxoplasmosis. OIE terrestrial manual. Vol 2, Chapter 2.9.10. CABI Publishing, Oxon, p 1284–1293

  • Dubey JP (2009) Toxoplasmosis in sheep-the last 20 years. Vet Parasitol 163:1–14

    Article  CAS  PubMed  Google Scholar 

  • Dubey JP, Beattie CP (1988) Toxoplasmosis in animals and man. CRC Press, Boca Raton, p 220

    Google Scholar 

  • Duncanson P, Terry RS, Smith JE, Hide G (2001) High levels of congenital transmission of Toxoplasma gondii in a commercial sheep flock. Int J Parasitol 31:1699–1703

    Article  CAS  PubMed  Google Scholar 

  • Edwards JF, Dubey JP (2013) Toxoplasma gondii abortion storm in sheep on a Texas farm and isolation of mouse virulent atypical genotype T. gondii from an aborted lamb from a chronically infected ewe. Vet Parasitol 192:129–136

    Article  PubMed  Google Scholar 

  • Evans HE, Sack WO (1973) Prenatal development of domestic and laboratory mammals: growth curves, external features and selected references. Anat Histol Embryol 2:11–45

    Article  CAS  Google Scholar 

  • Gumbrell RC (1990) Sheep abortion in New Zealand: 1989. Surveillance 17:22–23

    Google Scholar 

  • Hartley WJ, Jebson JL, McFarlan D (1954) New Zealand type II abortion in ewes. Aust Vet J 30:21–218

    Article  Google Scholar 

  • Hide G, Morely EK, Hughes JM, Gerwash OM, Elmahaishi S, Elmahaishi KH, Thomasson D, Wright EA, Williams RH, Murphy RG, Smith JE (2009) Evidence for high levels of vertical transmission in Toxoplasma gondii. Parasitol 136:1877–1885

    Article  CAS  Google Scholar 

  • Innes EA, Barley PM, Buxton D, Katzer F (2009) Ovin toxoplasmosis. Parasitol 136:1887–1894

    Article  Google Scholar 

  • Morely EK, Williams RH, Hughes JM, Terry RS, Duncanson P, Smith JE, Hide G (2005) Significant familial differences in the frequency of abortion and Toxoplasma gondii infection within a flock of Charollais sheep. Parasitol 131:1–5

    Article  Google Scholar 

  • Morely EK, Williams RH, Hughes JM, Thomasson D, Terry RS, Duncanson P, Smith JE, Hide G (2007) Evidence that primary infection of Charollais sheep with Toxoplasma gondii may not prevent fetal infection and abortion in subsequent lambings. Parasitol 135:169–173

    Google Scholar 

  • Orr MB (1989) Sheep abortions-in Vermay 1988. Surveillance 16:24–25

    Google Scholar 

  • Ortega-Mora LM, Gottstein B, Conraths FG, Buxton D (eds) (2007) Protozoal abortion in farm ruminants, guidelines for diagnosis and control. CABI publishing, Oxon, pp 122–210

    Google Scholar 

  • Plant JW, Beh KJ, Acland HM (1972) Laboratory findings from ovine abortion and perinatal mortality. Aust Vet J 48:558–561

    Article  CAS  PubMed  Google Scholar 

  • Rassouli M, Razmi GR, Movassaghi AR, Bassami MR, Sami M (2013) Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran. Korean J Vet Res 53:1–5

    Article  Google Scholar 

  • Razmi GR, Ghezi K, Mahouti A, Naseri Z (2010) A serological study and subsequent isolation of Toxoplasma gondii from aborted ovine fetuses in Mashhad area, Iran. J Parasitol 96:15–17

    Article  Google Scholar 

  • Skjerve E, Waldeland H, Nesbakken T, Kapperud G (1998) Risk factors for the presence of antibodies to Toxoplasma gondii in Norwegian slaughter lambs. Prev Vet Med 35:219–227

    Article  CAS  PubMed  Google Scholar 

  • Soleimani Rad J (2009) Histology, 3rd edn. Golban Medical Publications, Tehran, pp 1–6 (In Persian)

    Google Scholar 

  • Zedda MT, Rolesu S, Pau S, Rosati I, Ledda S, Satta G, Patta C, Masala G (2010) Epidemiological study of Toxoplasma gondii infection in ovine breeding. Zoonoses Public Health 57:102–108

    Article  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

    Ahmad Reza Movassaghi

  2. Center of Excellence in Ruminant Abortion and Neonatal Mortality, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

    Ahmad Reza Movassaghi

  3. Pathobiology Department, Shahmirzad School of Veterinary Medicine, Semnan University, Vali Asr area, Shahmirzad, P.O.Box: 35718-95589, Semnan, Iran

    Maryam Rassouli

  4. Department of Medical Parasitology & Entomology, Medical School, Zanjan University of Medical Sciences & Health Services, Zanjan, Iran

    Asghar Fazaeli

  5. Pathobiology Department, Veterinary Medicine Faculty, Semnan University, Semnan, Iran

    Mohammad Reza Salimi-Bejestani

Authors
  1. Ahmad Reza Movassaghi
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  2. Maryam Rassouli
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  3. Asghar Fazaeli
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  4. Mohammad Reza Salimi-Bejestani
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Corresponding author

Correspondence to Maryam Rassouli.

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Movassaghi, A.R., Rassouli, M., Fazaeli, A. et al. Outbreak of ovine congenital toxoplasmosis in Iran, confirmed by different diagnostic methods. J Parasit Dis 40, 152–156 (2016). https://doi.org/10.1007/s12639-014-0467-x

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  • DOI: https://doi.org/10.1007/s12639-014-0467-x

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