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Diffusion Tensor MRI of the Heart – In Vivo Imaging of Myocardial Fiber Architecture

  • Molecular Imaging (G Strijkers, Section Editor)
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Abstract

Despite many difficulties, the field of cardiac diffusion imaging is slowly but steadily making progress. In recent years it was demonstrated that reproducible measurement of diffusion parameters and fiber architecture in healthy and diseased hearts is possible. In this review we will discuss the basics of diffusion imaging as well as various reconstruction and analysis models. Furthermore, we cover the main challenges and proposed solutions that come with in vivo cardiac diffusion imaging. In vivo and ex vivo diffusion imaging of the heart has shown that the technique has great potential to better understand cardiac function, characterize cardiac pathology, and understand myofiber remodeling in response to injury or disease.

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Martijn Froeling, Gustav J. Strijkers, Steven A. Chamuleau, and Peter R. Luijten declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Radiology, University Medical Center, Utrecht, Netherlands

    Martijn Froeling & Peter R. Luijten

  2. Biomedical NMR, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands

    Martijn Froeling & Gustav J. Strijkers

  3. Department of Radiology, Academic Medical Center, Amsterdam, Netherlands

    Aart J. Nederveen

  4. Department of Cardiology, Division Heart & Lung, University Medical Center, Utrecht, Netherlands

    Steven A. Chamuleau

  5. University Medical Center Utrecht, Heidelberlaan 100 (Room Q04.4.313), Utrecht, 3584 CS, The Netherlands

    Martijn Froeling

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  1. Martijn Froeling
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Correspondence to Martijn Froeling.

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Froeling, M., Strijkers, G.J., Nederveen, A.J. et al. Diffusion Tensor MRI of the Heart – In Vivo Imaging of Myocardial Fiber Architecture. Curr Cardiovasc Imaging Rep 7, 9276 (2014). https://doi.org/10.1007/s12410-014-9276-y

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