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An Analysis of Medication Prescriptions for Hypertension in Urban and Rural Residents in Tianjin

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Abstract

Introduction

This study aims to examine the medication prescriptions for hypertension in Tianjin.

Methods

Patients with hypertension in Tianjin were enrolled in this study. The patients’ ages ranged from 35 to 75 years. A questionnaire survey and physical examination were completed to collect clinical data. Thereafter, a statistical analysis of the medication prescriptions was conducted with different age groups and different grades of hypertension.

Results

The results show that, in the total population, and for the young, middle-aged, and older groups, the proportions of single-drug use were 62.97%, 59.26%, 62.76%, and 63.49%, respectively, and the highest rate was for calcium channel blocker (CCB) use. The rates of the two drug classes were 24.51%, 29.63%, 25.13%, and 23.15%, respectively. The drug use rate of CCBs combined with angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor antagonists (ARBs) was the highest. The rates of the three drug classes were 4.08%, 4.94%, 4.36%, and 3.52%, respectively, and the highest was ACEI/ARB and CCB combined with diuretics. The rates of the four drug classes were low. Regarding the hypertension grade, in grade 1, grade 2, and grade 3, the rates of single-drug use were 63.53%, 62.69%, and 58.38%, respectively. The rates of the two drug classes were 24.62%, 23.97%, and 25.05%, while the rates of the three drug classes were 3.86%, 4.39%, and 5.34%, respectively.

Conclusion

The rate of single-drug use was high, and the rate of combined drug use in the youth group was slightly higher than in the middle-aged and older age groups. The combination of two drugs was common. In grades 2 and 3 hypertension, the rate of combined drug use remained low.

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Acknowledgements

Funding

This work was supported by the innovative demonstration project of Tianjin Hypertension and Coronary Heart Disease Prevention and Management Service Model and Department of Science and Technology of Tianjin city (15ZXHLSY00320) and the prevention and treatment of hypertension control target values of different risk stratification population and Department of Science and Technology of Tianjin city in Tianjin (16ZXMJSY00140).

Authorship

All named authors meet the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this article, take responsibility for the integrity of the work as a whole, and have given their approval for this version to be published.

Disclosures

Yingyi Zhang, Hua Yang, Ruiying Wang, Fumei Zhao, Ting Liu, Ying Zhang, Zhigang Guo and Hongliang Cong have nothing to disclose.

Compliance with Ethics Guidelines

This study was performed in accordance with the Helsinki Declaration of 1964 and its later amendments and approved by the ethics committee of Tianjin Chest Hospital. All participants provided written informed consent to participate in the study.

Data Availability

All data generated or analyzed during this study are included in this published article.

Author information

Author notes

  1. Yingyi Zhang and Hua Yang are co-first authors.

Authors and Affiliations

  1. Department of Cardiology, Tianjin Chest Hospital, Tianjin, 300222, China

    Yingyi Zhang, Hua Yang, Ruiying Wang, Zhigang Guo & Hongliang Cong

  2. Tianjin Cardiovascular Institute, Tianjin, 300222, China

    Fumei Zhao, Ting Liu & Ying Zhang

Authors
  1. Yingyi Zhang
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  2. Hua Yang
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  7. Zhigang Guo
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  8. Hongliang Cong
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Corresponding author

Correspondence to Hongliang Cong.

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Zhang, Y., Yang, H., Wang, R. et al. An Analysis of Medication Prescriptions for Hypertension in Urban and Rural Residents in Tianjin. Adv Ther 37, 4414–4426 (2020). https://doi.org/10.1007/s12325-020-01475-y

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  • DOI: https://doi.org/10.1007/s12325-020-01475-y

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