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The fungus Colletotrichum as a source for bioactive secondary metabolites

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Abstract

Colletotrichum sp. is a widely distributed fungal genus, which is mainly known to cause anthracnose on cereals, legumes, fruit trees, and vegetables. Even though many of the Colletotrichum sp. are plant pathogens, a variety of secondary metabolites with diverse bioactivities have been reported to be produced by this fungus. At least 109 secondary metabolites from the fungus Colletotrichum have been reported to date. They mostly include nitrogen-containing metabolites, sterols, terpenes, pyrones, phenolics, and fatty acids. Herein, the authors review the structurally interesting secondary metabolites produced by Colletotrichum and their biological activities.

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Acknowledgments

This work was supported by the National Research Foundation of Korea (NRF-2018R1A2B6001733 and NRF-2016R1A6A1A03007648) and the center for Women In Science, Engineering and Technology (WISET) grant funded by the Ministry of Science and ICT (MSIT) under the program for returners into R&D (WISET-201700780001).

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  1. College of Pharmacy and Innovative Drug Center, Duksung Women’s University, Seoul, 01369, Republic of Korea

    Jung Wha Kim & Sang Hee Shim

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Kim, J.W., Shim, S.H. The fungus Colletotrichum as a source for bioactive secondary metabolites. Arch. Pharm. Res. 42, 735–753 (2019). https://doi.org/10.1007/s12272-019-01142-z

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