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Flavonol glycosides from the aerial parts of Gynostemma pentaphyllum and their antioxidant activity

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Abstract

The phytochemical investigation of the aerial parts of Gynostemma pentaphyllum led to the isolation of a new flavonol glycoside, gynopentaphylloside (1), along with seven known compounds (2–8). The structure of the new compound was determined on the basis of 1D, 2D NMR and HRESIMS data as well as acid hydrolysis. The antioxidant activity of the isolates was evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay.

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Acknowledgments

This research was financially supported by the Ministry of Trade, Industry & Energy (MOTIE) and Korea Institute for Advancement of Technology (KIAT) through the Inter-ER Cooperation Projects (R0002021). The authors acknowledge the Korea Basic Science Institute for the NMR measurements.

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    Authors and Affiliations

    1. College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea

      Hari Jang, Jin Woo Lee, Chul Lee, Qinghao Jin, Myung Koo Lee, Chong Kil Lee, Mi Kyeong Lee & Bang Yeon Hwang

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    1. Hari Jang
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    2. Jin Woo Lee
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    3. Chul Lee
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    4. Qinghao Jin
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    5. Myung Koo Lee
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    7. Mi Kyeong Lee
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    Correspondence to Bang Yeon Hwang.

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    The authors have declared no conflict of interest.

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    Hari Jang and Jin Woo Lee contributed equally to this work.

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    Jang, H., Lee, J.W., Lee, C. et al. Flavonol glycosides from the aerial parts of Gynostemma pentaphyllum and their antioxidant activity. Arch. Pharm. Res. 39, 1232–1236 (2016). https://doi.org/10.1007/s12272-016-0793-x

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    • DOI: https://doi.org/10.1007/s12272-016-0793-x

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