Abstract
Chemical investigation the extract of Penicillium solitum GWQ-143 led to yield four new compounds penipyrols A–B (1–2) and peniamidones A–B (3–4), together with peniamidones C–D (5–6), which had been previously described as synthetic intermediates, not obtained from natural resource. The structures of those new compounds were established through extensive spectroscopic analysis. Compounds 1–6 exhibited great radical scavenging activities against DPPH with IC50 values ranged from 4.7 to 15.0 μM.
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Acknowledgments
This work was financially supported by the National Natural Science Foundation of China (Nos. 21372208 and 41176120), the National High Technology Research and Development Program of China (No. 2013AA092901) and the State Key Laboratory of Bio-organic and Natural Products Chemistry (SKLBNPC12331).
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Guo, W., Kong, X., Zhu, T. et al. Penipyrols A–B and peniamidones A–D from the mangrove derived Penicillium solitum GWQ-143. Arch. Pharm. Res. 38, 1449–1454 (2015). https://doi.org/10.1007/s12272-014-0513-3
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DOI: https://doi.org/10.1007/s12272-014-0513-3