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Combined Aerobic and Resistance Training for Peak Oxygen Uptake, Muscle Strength, and Hypertrophy After Coronary Artery Disease: a Systematic Review and Meta-Analysis

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Abstract

Maximal aerobic capacity measured as peak oxygen consumption (VO2peak), muscle strength, and muscle hypertrophy are the potent predictors of survival after coronary artery disease (CAD). The purpose of this study was to review the effects of combined aerobic training (AT) and resistance training (RT) on the three outcomes in CAD patients. Five electronic databases were searched. Combined AT and RT trials in 21 studies had a significantly greater favorable effect on all three outcomes compared with control groups (CON). In subgroup analyses for VO2peak, longer session duration and shorter post-CAD period were associated with larger effect size (ES). For muscle strength, higher training volume, longer post-CAD period, and younger age were associated with larger ES. In hypertrophy, longer training duration was associated with larger ES. Moderate intensity, 2–3 days per week, 50 min (AT), three sets of 10–12 repetitions, and seven exercises (RT) for 14 weeks are recommended.

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Funding

This study was not funded by any means.

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Authors and Affiliations

  1. Department of Kinesiology and Health Education, College of Education, University of Texas at Austin, Austin, TX, USA

    Junghoon Lee & Audrey J. Stone

  2. Department of Human Movement Science, Incheon National University, Incheon, Republic of Korea

    Ruda Lee

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  1. Junghoon Lee
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  2. Ruda Lee
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Contributions

Study concept and design: J.L.; researched data: J.L. and R.L.; drafting and revising the manuscript: J.L. and A.J.S.

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Correspondence to Audrey J. Stone.

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Associate Editor Domingo A. Pascual-Figal oversaw the review of this article

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Lee, J., Lee, R. & Stone, A.J. Combined Aerobic and Resistance Training for Peak Oxygen Uptake, Muscle Strength, and Hypertrophy After Coronary Artery Disease: a Systematic Review and Meta-Analysis. J. of Cardiovasc. Trans. Res. 13, 601–611 (2020). https://doi.org/10.1007/s12265-019-09922-0

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  • DOI: https://doi.org/10.1007/s12265-019-09922-0

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