Skip to main content
SpringerLink
Log in

Altered Protein Profiling in Tears from Patients in a Traumatic Vegetative State

  • Research Highlight
  • Published:
Neuroscience Bulletin Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Bernat JL. Chronic disorders of consciousness. Lancet 2006, 367: 1181–1192.

    Article  PubMed  Google Scholar 

  2. Laureys S, Celesia GG, Cohadon F, Lavrijsen J, León-Carrión J, Sannita WG, et al. Unresponsive wakefulness syndrome: a new name for the vegetative state or apallic syndrome. BMC Med 2010, 8: 68.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Monti MM, Laureys S, Owen AM. The vegetative state. BMJ 2010, 341: c3765.

    Article  PubMed  Google Scholar 

  4. Tang Q, Zhang C, Wu X, Duan W, Weng W, Feng J, et al. Comprehensive proteomic profiling of patients’ tears identifies potential biomarkers for the traumatic vegetative state. Neurosci Bull 2018, 34: 626–638.

    Article  CAS  PubMed  Google Scholar 

  5. Bao W, He F, Yu L, Gao J, Meng F, Ding Y, et al. Complement cascade on severe traumatic brain injury patients at the chronic unconscious stage: implication for pathogenesis. Expert Rev Mol Diagn 2018: 1–6.

  6. Shlosberg D, Benifla M, Kaufer D, Friedman A. Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury. Nat Rev Neurol 2010, 6: 393–403.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  7. Giacino JT, Fins JJ, Laureys S, Schiff ND. Disorders of consciousness after acquired brain injury: the state of the science. Nat Rev Neurol 2014, 10: 99–114.

    Article  PubMed  Google Scholar 

  8. Fernandez-Espejo D, Owen AM. Detecting awareness after severe brain injury. Nat Rev Neurosci 2013, 14: 801–809.

    Article  PubMed  CAS  Google Scholar 

  9. Wang KK, Ottens AK, Liu MC, Lewis SB, Meegan C, Oli MW, et al. Proteomic identification of biomarkers of traumatic brain injury. Expert Rev Proteomics 2005; 2:603–614.

    Article  PubMed  CAS  Google Scholar 

  10. Wu K, Zhang Y. Clinical application of tear proteomics: present and future prospects. Proteomics Clin Appl 2007, 1: 972–982.

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

This highlight was supported by grants from the National Natural Science Foundation of China (81671143) and the Science and Technology Plan of Zhejiang Province (2017C03011), China.

Author information

Authors and Affiliations

  1. Department of Neurology, First Affiliated Hospital, Collaborative Innovation Center for Brain Science, Zhejiang University School of Medicine, Hangzhou, 310003, China

    Hai Zou, Wangxiao Bao & Benyan Luo

  2. Department of Cardiology, Zhejiang Province People’s Hospital, Hangzhou, 310003, China

    Hai Zou

  3. People’s Hospital of Hangzhou Medical College, Hangzhou, 310003, China

    Hai Zou

Authors
  1. Hai Zou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wangxiao Bao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Benyan Luo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Benyan Luo.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zou, H., Bao, W. & Luo, B. Altered Protein Profiling in Tears from Patients in a Traumatic Vegetative State. Neurosci. Bull. 34, 713–714 (2018). https://doi.org/10.1007/s12264-018-0265-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12264-018-0265-z

Keywords

Search

Navigation