Abstract
A putative gene for a transcriptional regulator (ophR) was detected near each copy of the duplicated phthalate-degrading operon of Rhodococcus sp. DK17. Sequence analysis and molecular modeling indicate that OphR belongs to the IclR family of transcriptional regulators and possesses the N-terminal DNA-binding and C-terminal effector-binding domains. DNA-binding assays demonstrate that OphR regulates the phthalate operon by binding to the ophA1-ophR intergenic region.
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This work was financially supported by a grant from the Ministry of Oceans and Fisheries, Korea to the Korea Polar Research Institute (Project PM13030).
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Choi, K.Y., Kang, B.S., Nam, M.H. et al. Functional Identification of OphR, an IclR Family Transcriptional Regulator Involved in the Regulation of the Phthalate Catabolic Operon in Rhodococcus sp. Strain DK17. Indian J Microbiol 55, 313–318 (2015). https://doi.org/10.1007/s12088-015-0529-5
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DOI: https://doi.org/10.1007/s12088-015-0529-5