Skip to main content
SpringerLink
Log in

ZnO nanorods bonded polythiophene nanocomposite: an enhanced electrochemical voltammetric biosensing of L-tryptophan

  • Published:
Bulletin of Materials Science Aims and scope Submit manuscript

Abstract

Electrostatically fused nanocomposite of zinc oxide (ZnO) nanorods affixed with polythiophene (PT) was successfully illustrated for effective voltammetric biosensing of L-tryptophan (L-Try) in this work. Structural characterization confirms the in-situ composite formation of PT @ ZnO and its BET analysis reveals the porous nature of as-synthesized material having the specific surface area of 4.953 m2 g–1 and average pore diameter of 2.153 nm, respectively. PT @ ZnO exhibits superior electrochemical performance towards L-Try in phosphate buffer solution of pH 7 by the movement of fast electron-transfer rate because of effective interaction between indole group of L-Try and PT @ ZnO nanocomposite. That is, the sulphur group in PT easily attached with the amine group of L-Try demonstrated the linear increase of peak current with increasing concentration in the range of L-Try 100 nM–1 mM having detection limit of 8.5 nM. The invented biosensor shows extraordinary selectivity among other physiological substances and also exposes high stability, repeatability and reproducibility. The practical utility of PT-ZnO/glassy carbon electrode tested with the concentration of L-Try in peanut extract showed preferable results.

Graphical Abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Scheme 1
Figure 6

Similar content being viewed by others

References

  1. Aktas O¸ Yokus F, Kardas O, Akyıldırım T, Eren N, Atar M L et al 2016 Sens. Actuators B 233 47

  2. Guo Y, Guo S, Fang Y and Donga S 2010 Electrochim. Acta 55 3927

    Article  CAS  Google Scholar 

  3. Haldorai Y, Yeon S H, Huh Y S and Han Y K 2017 Sens. Actuators B 239 1221

    Article  CAS  Google Scholar 

  4. Palego L, Betti L, Rossi A and Giannaccini G 2016 J. Amino Acids Article ID 8952520 13

  5. Thomas T, Mascarenhas R J, D’Souza O J, Martis P, Dalhalle J and Kumara Swamy B E 2013 J. Colloid Interface Sci. 402 223

    Article  CAS  Google Scholar 

  6. Zhang C, Zhang Q, Song X, Pang Y, Song Y, Wang Y et al 2019 Aquaculture 511 734205

    Article  CAS  Google Scholar 

  7. Yılmaz C and Gökmen V 2018 Food Chem. 243 420

    Article  Google Scholar 

  8. Faure P, Flore P, Montérémal J and Ducros V 2017 J. Chromatogr. B 1054 36

    Article  Google Scholar 

  9. Nevídalová H, Michalcová L and Glatz Z 2020 J. Sep. Sci. 43 4225

    Article  Google Scholar 

  10. Fan M, Lu D, You R, Chen C, Lu Y, Wu Y et al 2020 Anal. Chim. Acta 1119 52

    Article  CAS  Google Scholar 

  11. Tedetti M, Joffre P and Goutx M 2013 Sens. Actuators B Chem. 182 416

    Article  CAS  Google Scholar 

  12. Li Y, Wang J, Yang Y and Han S 2020 J. Bio. Chemilumin. 35 773

    CAS  Google Scholar 

  13. Pushpanjali P A, Manjunatha J G and Shreenivas M T 2019 Chem. Select. 4 13427

    CAS  Google Scholar 

  14. Chandrashekar B N, Kumara Swamy B E, Pandurangachar M, Sharath Shankar S, Gilbert O, Manjunatha J G et al 2010 Int. J. Electrochem. Sci. 5 578

    Google Scholar 

  15. Madikeri M, Charithra and Manjunatha J G 2020 J. Electrochem. Sci. Eng. 10 29

  16. Hareesha N, Gangadharappa J, Manjunatha G, Raril C and Tigari G 2019 Adv. Pharm. Bull. 9 132

    Article  CAS  Google Scholar 

  17. Manjunatha J G, Deraman M, Basri N H and Talib I A 2014 Adv. Mater. Res. 895 447

    Article  Google Scholar 

  18. Tigari G and Manjunatha J G 2020 J. Sci. Adv. Mater. Dev. 5 56

    Google Scholar 

  19. Hareesha N and Manjunatha J G 2020 J. Iran Chem. Soc. 17 1507

    Article  CAS  Google Scholar 

  20. Anusha J R, Je Kim H, Fleminga A T, Das S J, Yu K H, Kim B C et al 2014 Sens. Actuators B 202 827

    Article  CAS  Google Scholar 

  21. You X, Pikul J H, King W P and Pak J 2013 J. Appl. Phys. Lett. 102 253103

    Article  Google Scholar 

  22. Arya S K, Saha S, Ramirez-Vick J E, Gupta V, Bhansali S and Singh S P 2012 Anal. Chim. Acta 737 1

    Article  CAS  Google Scholar 

  23. Beitollahi H, Gholami A and Ganjali M R 2015 Mater. Sci. Eng. C 57 107

    Article  CAS  Google Scholar 

  24. Shukla M, Pramila Dixit T, Prakash R, Palani I A and Singh V 2017 Appl. Surf. Sci. 422 798

    Article  CAS  Google Scholar 

  25. Naganathan D, Thangamani P, Selvam T and Narayanasamy T 2017 Microchim. Acta 185 1

    Google Scholar 

  26. Senthilkumar B, Thenamirtham P and Kalai Selvan R 2011 Appl. Surf. Sci. 257 9063

    Article  CAS  Google Scholar 

  27. Zanardi C, Terzi F and Seeber R 2013 Anal. Bioanal. Chem. 405 509

    Article  CAS  Google Scholar 

  28. Husain A, Shariq M U and Mohammad F 2020 Materialia 9 100599

    Article  CAS  Google Scholar 

  29. Bora C, Pegu R, Saikia B J and Dolui S K 2014 Polym. Int. 63 2061

    Article  CAS  Google Scholar 

  30. Schmitt D A, Nesbit J B, Hurlburt B K, Cheng H and Maleki S J 2010 J. Agr. Food Chem. 58 1138

    Article  CAS  Google Scholar 

  31. Erdogan M K, Karakisla M and Sacak M 2012 J. Macromol. Sci. 49 473

    Article  CAS  Google Scholar 

  32. Brahma S, Rao K J and Shivashankar S 2010 Bull. Mater. Sci. 33 89

    Article  CAS  Google Scholar 

  33. Xu S H, Li S Y, Wei Y X, Zhang L and Xu F 2010 React. Kinet. Mech. Cat. 101 237

    Article  CAS  Google Scholar 

  34. Thamer A, Faisal A, Abed A and Khalef W 2020 J. Nanopart. Res. 74 1

    Google Scholar 

  35. Marshall N, James W, Fulmer J, Crittenden S, Thompson A B, Ward P A et al 2019 Inorg. Chem. 58 5561

    Article  CAS  Google Scholar 

  36. Ributa S H, Che Abdullah C A and Mohammad Yusoff M Z 2019 Results Phys. 13 102146

    Article  Google Scholar 

  37. Aljaafari A, Ahmed F, Awada C and Shaalan N M 2020 Front. Chem. 8 456

    Article  CAS  Google Scholar 

  38. Tripathi A, Mishra S K, Bahadur I and Shukla R K 2015 J. Mater. Sci.: Mater. Electron. 26 7421

    CAS  Google Scholar 

  39. Wu X, Wen L, Lv K, Deng K, Tang D, Ye H et al 2015 Appl. Surf. Sci. 358 130

    Article  CAS  Google Scholar 

  40. Shah R, Kausar A, Muhammad B and Khan M 2016 Compos. Interfaces 23 887

    Article  CAS  Google Scholar 

  41. Taghizadeh S M, Lal N, Ebrahiminezhad A, Moeini F, Seifan M, Ghasemi Y et al 2020 Nanomaterials 10 530

    Article  CAS  Google Scholar 

  42. Prongmanee W, Alam I and Asanithi P 2019 J. Taiwan Inst. Chem. Eng. 102 415

    Article  CAS  Google Scholar 

  43. Safavi A and Momenia S 2010 Electroanalysis 22 2848

    Article  CAS  Google Scholar 

  44. Fan Y, Liu J H, Lu H T and Zhang Q 2011 Microchim. Acta 173 241

    Article  CAS  Google Scholar 

  45. Prabhu P, Suresh Babu R and Sriman Narayanan S 2011 Colloids Surf. 87 103

    Article  CAS  Google Scholar 

  46. Xu C X, Huang K J, Fan Y, Wu Z W, Li J and Gan T 2012 Mater. Sci. Eng. C 32 969

    Article  CAS  Google Scholar 

  47. Tang X F, Liu Y, Hou H Q and You T Y 2010 Talanta 80 2182

    Article  CAS  Google Scholar 

  48. Liu X, Luo L Q, Ding Y P and Ye D X 2011 Bioelectrochemistry 82 38

    Article  CAS  Google Scholar 

  49. Beitollahi H, Garkani-Nejad F, Tajik S and Ganjali M R 2019 Iran. J. Pharm. Res. 18 80

    CAS  Google Scholar 

  50. Ye D, Luo L, Ding Y, Liu B and Liu X 2012 Analyst 137 2840

    Article  CAS  Google Scholar 

  51. Zhu S, Zhang J, Zhao X, Wang H, Xu G and You J 2014 Microchim. Acta 181 445

    Article  CAS  Google Scholar 

  52. GunaVathana S D, Thivya P, Wilson J and Peter A C 2020 J. Mol. Struct. 1205 127649

    Article  CAS  Google Scholar 

  53. GunaVathana S D, Wilson J, Prashanthi R and Peter A C 2021 Inorg. Chem. Commun. 124 108398

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physics, Raja Doraisingam Government Arts College, Affiliated to Alagappa University, Karaikudi, 630 561, India

    S Dheepthi Gunavathana & A Cyrac Peter

  2. Department of Bioelectronics and Biosensors, Alagappa University, Karaikudi, 630 001, India

    S Girija & J Wilson

Authors
  1. S Dheepthi Gunavathana
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S Girija
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J Wilson
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A Cyrac Peter
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to A Cyrac Peter.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOC 804 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Dheepthi Gunavathana, S., Girija, S., Wilson, J. et al. ZnO nanorods bonded polythiophene nanocomposite: an enhanced electrochemical voltammetric biosensing of L-tryptophan. Bull Mater Sci 45, 57 (2022). https://doi.org/10.1007/s12034-021-02630-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s12034-021-02630-z

Keywords

Search

Navigation