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Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens

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The objective of this study was to compare the effects of nanoselenium (NS) and selenium yeast (SY) on the performance, egg selenium (Se) concentration, and anti-oxidative capacity of hens. A total of 216 Brown Hy-line hens (29-week old) were randomly allocated into three treatments (6 replicate/treatment, 12 hens/replicate). The pre-trial period lasted 7 days, and the experimental period lasted 35 days. Dietary treatments included corn-soybean meal basal diet (containing 0.16 μg Se/g, as control group), and basal diet supplemented with 0.3 mg Se/kg diet (Se was from NS or SY), called as SY group or NS group, respectively. At the end of the experiment, one hen per replicate from each treatment was slaughtered. Liver, spleen, and kidney tissues were sampled for the determination of Se concentrations. The results showed that NS or SY supplement significantly improved feed conversion ratio (P < 0.05), soft broken egg rate (P < 0.05), and the serum T-AOC value (P < 0.05) when compared with control group. Remarkably, the deposition of Se increased significantly (P < 0.05) and equivalently in egg, liver, and kidney of hens supplemented with both NS and SY. Interestingly, SY supplement also enhanced the serum CAT and SOD activities (P < 0.05), NS but not SY significantly reduced serum MDA (P < 0.05), whereas RT-PCR results did not show significant differences in the mRNA levels of antioxidant genes among three groups (P > 0.05). Taken together, dietary supplemented with SY or NS improved the Se deposition in eggs, liver and kidney of laying hens, increased antioxidant activity, and NS supplement had greater Se deposition in the kidney tissue than SY supplement. SY or NS supplement could be considered to be applied for Se-enriched egg production.

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References

  1. Ahmad H, Tian J, Wang J, Khan MA, Wang Y, Zhang L, Wang T (2012) Effects of dietary sodium selenite and selenium yeast on antioxidant enzyme activities and oxidative stability of chicken breast meat. J Agric Food Chem 60:7111–7120

    Article  CAS  Google Scholar 

  2. Ashmead HD (1991) Comparative intestinal absorption and subsequent metabolism of metal amino acid chelates and inorganic metal salts. Biol Trace Elem Res:306–319

  3. Behne D, Kyriakopoulos A (2001) Mammalian selenium-containing proteins. Annu Rev Nutr 21:453–473

    Article  CAS  Google Scholar 

  4. Boostani A, Sadeghi AA, Mousavi SN, Chamani M, Kashan N (2015) Effects of organic, inorganic, and nano-Se on growth performance, antioxidant capacity, cellular and humoral immune responses in broiler chickens exposed to oxidative stress. Livest Sci 178:330–336

    Article  Google Scholar 

  5. Bugel S, Larsen EH, Sloth JJ, Flytlie K, Overvad K, Steenberg LC et al (2008) Absorption, excretion, and retention of selenium from a high selenium yeast in men with a high intake of selenium. Food Nutr Res 52:1642

    Article  Google Scholar 

  6. Cai SJ, Wu CX, Gong LM, Song T, Wu H, Zhang LY (2012) Effects of nano-selenium on performance, meat quality, immune function, oxidation resistance, and tissue selenium content in broilers. Poult Sci 91:2532–2539

    Article  CAS  Google Scholar 

  7. Cao C, Zhao X, Fan R, Zhao J, Luan Y, Zhang Z, Xu S (2016) Dietary selenium increases the antioxidant levels and ATPase activity in the arteries and veins of poultry. Biol Trace Elem Res 172:222–227

    Article  CAS  Google Scholar 

  8. Delezie E, Rovers M, Van der Aa A, Ruttens A, Wittocx S, Segers L (2014) Comparing responses to different selenium sources and dosages in laying hens. Poult Sci 93:3083–3090

    Article  CAS  Google Scholar 

  9. Gangadoo S, Dinev I, Willson NL, Moore RJ, Chapman J, Stanley D (2020) Nanoparticles of selenium as high bioavailable and non-toxic supplement alternatives for broiler chickens. Environ Sci Pollut Res Int 27(14):16159–16166

    Article  CAS  Google Scholar 

  10. Han XJ, Qin P, Li WX, Ma QG, Ji C, Zhang JY, Zhao LH (2017) Effect of sodium selenite and selenium yeast on performance, egg quality, antioxidant capacity, and selenium deposition of laying hens. Poult Sci 96:3973–3980

    Article  CAS  Google Scholar 

  11. Hoffmann PR, Berry MJ (2008) The influence of selenium on immune responses. Mol Nutr Food Res 52:1273–1280

    Article  CAS  Google Scholar 

  12. Hu CH, Li YL, Xiong L, Zhang HM, Song J, Xia MS (2012) Comparative effects of nano elemental selenium and sodium selenite on selenium retention in broiler chickens. Anim Feed Sci Technol 177:204–210

    Article  CAS  Google Scholar 

  13. Huang Y, Li W, Xu D, Li B, Tian Y, Zan L (2016) Effect of dietary selenium deficiency on the cell apoptosis and the level of thyroid hormones in chicken. Biol Trace Elem Res 171:445–452

    Article  CAS  Google Scholar 

  14. Jing CL, Dong XF, Wang ZM, Liu S, Tong JM (2015) Comparative study of DL-selenomethionine vs sodium selenite and seleno-yeast on antioxidant activity and selenium status in laying hens. Poult Sci 94:965–975

    Article  CAS  Google Scholar 

  15. Katarzyna B, Taylor RM, Szpunar J, Lobinski R, Sunde RA (2020) Identification and determination of selenocysteine, selenosugar, and other selenometabolites in turkey liver. Metallomics 12(5):758–766

    Article  CAS  Google Scholar 

  16. Khan MT, Mahmud A, Zahoor I, Javed K (2017) Organic and inorganic selenium in Aseel chicken diets: effect on hatching traits. Poult Sci 96:1466–1472

    Article  CAS  Google Scholar 

  17. Kim WR, Flamm SL, Di Bisceglie AM, Bodenheimer HC, Public Policy Committee of the American Association for the Study of Liver D (2008) Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease. Hepatology 47:1363–1370

    Article  CAS  Google Scholar 

  18. Leeson S, Namkung H, Caston L, Durosoy S, Schlegel P (2008) Comparison of selenium levels and sources and dietary fat quality in diets for broiler breeders and layer hens. Poult Sci 87:2605–2612

    Article  CAS  Google Scholar 

  19. Li JL, Sunde RA (2016) Selenoprotein transcript level and enzyme activity as biomarkers for selenium status and selenium requirements of chickens (Gallus gallus). PLoS One 11(4):e0152392

    Article  Google Scholar 

  20. Li JL, Zhang L, Yang ZY, Zhang ZY, Jiang Y, Gao F, Zhou GH (2018) Effects of different selenium sources on growth performance, antioxidant capacity and meat quality of local Chinese Subei chickens. Biol Trace Elem Res 181:340–346

    Article  CAS  Google Scholar 

  21. Lin X, Yang T, Li H, Ji Y, Zhao Y, He J (2020) Interactions between different selenium compounds and essential trace elements involved in the antioxidant system of laying hens. Biol Trace Elem Res 193:252–260

    Article  CAS  Google Scholar 

  22. Liu Y, Wan D, Zhou X, Ruan Z, Zhang T, Wu X, Yin Y (2019) Effects of dynamic feeding low- and high-methionine diets on the variation of glucose and lipid metabolism-related genes in the liver of laying hens. Poult Sci 98:2231–2240

    Article  CAS  Google Scholar 

  23. Liu H, Yu Q, Fang C, Chen S, Tang X, Ajuwon KM, Fang R (2020) Effect of selenium source and level on performance, egg quality, egg selenium content, and serum biochemical parameters in laying hens. Foods. 9(1):68. https://doi.org/10.3390/foods9010068

    Article  CAS  PubMed Central  Google Scholar 

  24. Lu J, Qu L, Shen MM, Hu YP, Guo J, Dou TC, Wang KH (2018) Comparison of dynamic change of egg selenium deposition after feeding sodium selenite or selenium-enriched yeast. Poult Sci 97:3102–3108

    Article  CAS  Google Scholar 

  25. Lu J, Qu L, Shen MM, Wang XG, Guo J, Hu YP, Dou TC, Wang KH (2019) Effects of high-dose selenium-enriched yeast on laying performance, egg quality, clinical blood parameters, organ development, and selenium deposition in laying hens. Poult Sci 98(6):2522–2530

    Article  CAS  Google Scholar 

  26. Meng T, Liu YL, Xie CY, Zhang B, Huang YQ, Zhang YW, Yao Y, Huang R, Wu X (2019) Effects of different selenium sources on laying performance, egg selenium concentration, and antioxidant capacity in laying hens. Biol Trace Elem Res 189:548–555

    Article  CAS  Google Scholar 

  27. Mohapatra P, Swain RK, Mishra SK, Behera T, Swain P, Mishra SS et al (2014) Effects of dietary nano-selenium on tissue selenium deposition, antioxidant status and immune functions in layer chicks. Int J Pharmacol 10:160–167

    Article  CAS  Google Scholar 

  28. Nettleford SK, Prabhu KS (2018) Selenium and selenoproteins in gut inflammation-a review. Antioxidants (Basel) 7

  29. Pan C, Huang K, Zhao Y, Qin S, Chen F, Hu Q (2007) Effect of selenium source and level in hen's diet on tissue selenium deposition and egg selenium concentrations. J Agric Food Chem 55:1027–1032

    Article  CAS  Google Scholar 

  30. Paton ND, Cantor AH, Pescatore AJ, Ford MJ, Smith CA (2002) The effect of dietary selenium source and level on the uptake of selenium by developing chick embryos. Poult Sci 81:1548–1554

    Article  CAS  Google Scholar 

  31. Payne RL, Lavergne TK, Southern LL (2005) Effect of inorganic versus organic selenium on hen production and egg selenium concentration. Poult Sci 84:232–237

    Article  CAS  Google Scholar 

  32. Peng D, Zhang J, Liu Q, Taylor EW (2007) Size effect of elemental selenium nanoparticles (nano-Se) at supranutritional levels on selenium accumulation and glutathione S-transferase activity. J Inorg Biochem 101:1457–1463

    Article  CAS  Google Scholar 

  33. Qazi IH, Angel C, Yang H, Pan B, Zoidis E, Zeng CJ et al (2018) Selenium, selenoproteins, and female reproduction: a review. Molecules 23

  34. Qin SY, Chen F, Guo YG, Huang BX, Zhang JB, Ma JF (2014) Effects of nano-selenium on kidney selenium contents, glutathione peroxidase activities and GPx-1 mRNA expression in mice. Adv Mater Res 1051:383–387

    Article  Google Scholar 

  35. Schrauzer GN (2003) The nutritional significance, metabolism and toxicology of selenomethionine. 47:73–112

  36. Shi L, Xun W, Yue W, Zhang C, Ren Y, Shi L, Wang Q, Yang R, Lei F (2011) Effect of sodium selenite, Se-yeast and nano-elemental selenium on growth performance, Se concentration and antioxidant status in growing male goats. Small Ruminant Res 96:49–52

    Article  Google Scholar 

  37. Surai PF, Kochish II, Fisinin VI, Kidd MT (2019) Antioxidant defence systems and oxidative stress in poultry biology: an update. Antioxidants (Basel):8

  38. Sunde RA, Li J-L, Taylor RM (2016) Insights for setting of nutrient requirements, gleaned by comparison of selenium status biomarkers in turkeys and chickens versus rats, mice, and lambs. Adv Nutr: An Int Rev J 7(6):1129–1138

    Article  CAS  Google Scholar 

  39. Utterback PL, Parsons CM, Yoon I, Butler J (2005) Effect of supplementing selenium yeast in diets of laying hens on egg selenium content. Poult Sci 84:1900–1901

    Article  CAS  Google Scholar 

  40. Zhao L, Sun L-H, Huang J-Q, Briens M, Qi D-S, Xu S-W, Lei XG (2017) A novel organic selenium compound exerts unique regulation of selenium speciation, selenogenome, and selenoproteins in broiler chicks. J Nutr 147(5):789–797

    Article  CAS  Google Scholar 

  41. Zhang J, Wang X, Xu T (2008) Elemental selenium at nano size (nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: comparison with se-methylselenocysteine in mice. Toxicol Sci 101:22–31

    Article  CAS  Google Scholar 

  42. Zhang Y, Zhu S, Wang X, Wang C, Li F (2011) The effect of dietary selenium levels on growth performance, antioxidant capacity and glutathione peroxidase 1 (GSHPx1) mRNA expression in growing meat rabbits. Anim Feed Sci Tech 169:259–264

    Article  CAS  Google Scholar 

  43. Zhou X, Wang Y (2011) Influence of dietary nano elemental selenium on growth performance, tissue selenium distribution, meat quality, and glutathione peroxidase activity in Guangxi Yellow chicken. Poult Sci 90:680–686

    Article  CAS  Google Scholar 

  44. Zhu C, Zhang S, Song C, Zhang Y, Ling Q, Hoffmann PR, Li J, Chen T, Zheng W, Huang Z (2017) Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-kappaB mediated hyper inflammation. J Nanobiotechnol 15:20

    Article  Google Scholar 

  45. Zoidis E, Pappas AC, Georgiou CA, Komaitis E, Feggeros K (2010) Selenium affects the expression of GPx4 and catalase in the liver of chicken. Comp Biochem Physiol B Biochem Mol Biol 155:294–300

    Article  CAS  Google Scholar 

  46. Yang Z, Liu C, Zheng W, Teng X, and Li S (2016) The functions of antioxidants and heat shock proteins are altered in the immune organs of selenium-deficient broiler chickens. Biol Trace Elem Res 169:341-351.

  47. NRC (1994) Nutrient requirements of poultry, 9th edn. National Academy Press, Washington, DC.

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Funding

This research received financial support from national key research and development program of China (2016YFD0200900); Poverty Alleviation through Agricultural Projects from the Agricultural Office of Chinese Academy of Sciences; Agricultural innovation project of Hunan Province (2019TD01).

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Authors and Affiliations

  1. Hunan Co-Innovation Center of Safety Animal Production, College of Animal Science and Technology & College of Resources and Environment, Hunan Agricultural University, Changsha, 410128, China

    Tian-Tian Meng, Xue Lin, Chun-Yan Xie, Jian-Hua He, Yi-Qiang Huang & Xin Wu

  2. Key Laboratory of Agro-ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production; Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, 410125, China

    Tian-Tian Meng & Xin Wu

  3. Hunan Provincial Research Center of Mineral Element Nutrition Engineering Technology, Xing-Jia Bio-engineering Co., Ltd., Changsha, 410300, China

    Yang-Kui Xiang & Yi-Qiang Huang

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  1. Tian-Tian Meng
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Correspondence to Chun-Yan Xie.

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Animal experiments were approved by the Animal Care Committee of the Institute of Subtropical Agriculture, Chinese Academy of Science.

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Meng, TT., Lin, X., Xie, CY. et al. Nanoselenium and Selenium Yeast Have Minimal Differences on Egg Production and Se Deposition in Laying Hens. Biol Trace Elem Res 199, 2295–2302 (2021). https://doi.org/10.1007/s12011-020-02349-8

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