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Effects of Environmental Zinc Deficiency on Antioxidant System Function in Wumeng Semi-fine Wool Sheep

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Abstract

The purpose of this study was to explore the effect of zinc deficiency on the antioxidant system function in Wumeng semi-fine wool sheep. The content of mineral elements in soil, forage, and animal tissues were analyzed by inductively coupled plasma atomic emission spectrometry. The blood parameters were analyzed by automatic blood cell analyzer, and the serum biochemical indexes were analyzed by automatic biochemical analyzer. The results showed that the concentrations of zinc in soil and herbage were significantly lower (P < 0.01) in affected than control pasture, and calcium content was also significantly higher (P < 0.01). The concentrations of zinc in blood and liver from the affected animals were significantly lower (P < 0.01) than those in healthy animals, and calcium content was also significantly higher (P < 0.01). The content of hemoglobin, erythrocyte number, packed cell volume, lactate dehydrogenase, and alkaline phosphatase activity in the blood from affected areas were significantly lower (P < 0.01) than those in healthy animals. The activities of aspartate aminotransferase and alanine transaminase were also higher (P < 0.01). Serum superoxide dismutase, serum glutathione peroxidase, total antioxidant capacity, and catalase from affected areas were significantly lower (P < 0.01) than those in healthy animals. Malondialdehyde content was also higher (P < 0.01). There were no differences in other blood mineral element concentrations, blood indexes, and serum biochemical values. It was concluded that zinc deficiency in the Wumeng semi-fine wool sheep is mainly caused by the low content of zinc in soil and forage, and the zinc deficiency seriously affected the antioxidant system function.

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Funding

This work was supported by the Project of National Key Research and Development Program of China in 13th Five-year Plan (2016YFC0502601) and the National Natural Science Foundation of China (41671041).

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Authors and Affiliations

  1. School of Life Science and Engineering, Southwest University of Science and Technology, Mianyang, 621010, China

    Chunjie Song & Xiaoyun Shen

  2. State Engineering Technology Institute for Kast Desertification Control, Guizhou Normal University, Guiyang, 550025, China

    Xiaoyun Shen

  3. World Bank Poverty Alleviation Project Office in Guizhou, Southwest China, Guiyang, 550004, China

    Xiaoyun Shen

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  1. Chunjie Song
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Correspondence to Xiaoyun Shen.

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Ethics Statement

The Wumeng semi-fine sheep used in these studies were cared as per outlined in the Guide for the Care and Use of Animals in Agricultural Research and Teaching Consortium (Federation of Animals Science Societies. 2010). Sample collections in animals were approved by the Southwest University of Science and Technology in China, Institutional Animal Care and Use Committee (Project A00572).

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Song, C., Shen, X. Effects of Environmental Zinc Deficiency on Antioxidant System Function in Wumeng Semi-fine Wool Sheep. Biol Trace Elem Res 195, 110–116 (2020). https://doi.org/10.1007/s12011-019-01840-1

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