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Tooth Element Levels Indicating Exposure Profiles in Diabetic and Hypertensive Subjects from Mysore, India

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Abstract

Element contents of teeth elucidate exposure nature, but less is known about association of tooth element concentrations of diabetics and hypertensives with exposure profile. Present study aims to estimate copper, chromium, iron, zinc, nickel, and lead concentrations in the permanent teeth of control, diabetic, and hypertensive subjects from Mysore. The results show that lead levels of teeth (Pb-T) are higher in the hypertensives and diabetics, whereas copper levels of teeth (Cu-T) are lower in the hypertensives and users of stainless steel utensils than that of controls and users of mixed utensils. The elevated Cu-T levels found in the users of mixed utensils that being made of several metals are ascribed to leaching effect of sour and spicy food of Indian cuisine. The element levels were influenced by diet (Zn-T), place of living, sex and income (Pb-T) of the subjects, but not by age, drinking water from different sources, and certain habits viz., smoking, alcohol consumption, chewing betel, and nut. Thus, it is evident that high Pb-T and low Cu-T levels may be related with diabetes and hypertension and high Pb-T and Cu-T levels, respectively, in the urbanites, and the users of mixed utensils may show different exposure profiles from environment and utensils.

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References

  1. Nowak B. Occurrence of heavy metals and sodium, potassium and calcium in human teeth. Analyst. 1995;120(3):747–50.

    Article  CAS  PubMed  Google Scholar 

  2. Sukumar A, Subramanian R (1999) Characterization of human teeth for trace elements. Proceedings of the second National Workshop on Development and use of Reference Materials. LATS/15/2000. Central Pollution Control Board, Delhi, pp:86-88

  3. Arora M, Kenedy BJ, Elhlou S, Pearson NJ, Walker DM, Bayl P, et al. Spatial distribution of lead in human primary teeth as a biomarker of pre- and neonatal lead exposure. Sci Total Environ. 2006;371(1–3):55–62.

    CAS  PubMed  Google Scholar 

  4. Malara P, Kwapulinski J, Malara B. Do the levels of selected metals differ significantly between the roots of carious and non-carious teeth? Sci Total Environ. 2006;369(1–3):59–68.

    CAS  PubMed  Google Scholar 

  5. Wilhelm M, Ewers U, Wittsiepe J, Furst P, Holzer J, Eberwein G, et al. Human biomonitoring studies in North Rhine-Westphalia, Germany. Int J Hyg Environ Health. 2007;210(3–4):307–18.

    Article  CAS  PubMed  Google Scholar 

  6. Haavikko K, Anttila A, Helle A, Vuori E. Lead concentrations of enamel and dentine of deciduous teeth of children from two Finnish towns. Arch Environ Health. 1984;39(2):78–84.

    CAS  PubMed  Google Scholar 

  7. Lane DW, Peach DF. Some observations on the trace element concentrations in human dental enamel. Biol Trace Elem Res. 1997;60(1–2):1–11.

    Article  CAS  PubMed  Google Scholar 

  8. Grandjean P, Jorgensen PJ. Retention of lead and cadmium in prehistoric and modern human teeth. Environ Res. 1990;53(1):6–15.

    Article  CAS  PubMed  Google Scholar 

  9. Rabinowitz MB, Wang JD, Soong WT. Dentine lead and child intelligence in Taiwan. Arch Environ Health. 1991;46(6):351–60.

    CAS  PubMed  Google Scholar 

  10. Nriagu J, Burt B, Linder A, Ismail A, Sohn W. Lead levels in blood and saliva in a low-income population of Detroit, Michigan. Int J Hyg Environ Health. 2006;209(2):109–21.

    Article  CAS  PubMed  Google Scholar 

  11. Haavikko K, Anttila A, Helle A, Pesonen E. Atherosclerosis precursors in Finnish children and adolescents. XIV. Zinc and copper concentrations in deciduous teeth. Acta Paediatr Scand Suppl. 1985;318:213–219.

    CAS  Google Scholar 

  12. Scharer K, Veits G, Brockhaus A, Ewers U. High lead content of deciduous teeth in chronic renal failure. Pediatr Nephrol. 1991;5(6):704–7.

    Article  CAS  PubMed  Google Scholar 

  13. Winneke G, Altmann L, Kramer U, Turfeld M, Behler R, Gutsmuths FJ, et al. Neurobehavioral and neurophysiological observations in six year old children with low lead levels in East and West Germany. Neurotoxicol. 1994;15(3):705–13.

    CAS  Google Scholar 

  14. Gomes VE, Rosario de Sousa Mda L, Barbosa F Jr, Krug FJ, Pereira Saraiva Mda C, Cury JA, et al. In vivo studies on lead content of deciduous teeth superficial enamel of preschool children. Sci Total Environ. 2004;320(1):25–35.

    Article  CAS  PubMed  Google Scholar 

  15. Anderson RA. Chromium and diabetes. Nutrition. 1999;15(9):720–22.

    Article  CAS  PubMed  Google Scholar 

  16. Rabinovitz H, Friedensohn A, Leibovitz A, Gabay G, Rocas C, Habot B. Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients. Int J Vitam Nutr Res. 2004;74(3):178–182.

    Article  CAS  PubMed  Google Scholar 

  17. Sukumar A, Subramanian R. Trace elements in scalp hair of manufacturers from Sivakasi, Tamilnadu. Sci Total Environ. 1992;114:161–168.

    Article  CAS  PubMed  Google Scholar 

  18. Brown CJ, Chenery SR, Smith B, Tomkins A, Roberts GJ, Sserunjogi L, et al. A sampling and analytical methodology for dental trace element analysis. Analyst. 2002;127(2):19–23.

    Article  Google Scholar 

  19. Subramanian R, Sukumar A. Biological reference materials and analysis of elements. Fresenius Z Anal Chem. 1988;332:623–626.

    Article  CAS  Google Scholar 

  20. Okamoto K. Preparation and certification of human hair powder reference material. Clin Chem. 1985;31(10):1952.

    Google Scholar 

  21. Tvinnereim HM, Eide R, Riise T, Fosse G, Wesenberg GR. Zinc in primary teeth from children in Norway. Sci Total Environ. 1999;226(2–3):201–12.

    Article  CAS  PubMed  Google Scholar 

  22. Rahman A, Maqbool E, Zuberi HS. Lead-associated deficits in stature, mental ability and behaviour in children in Karachi. Ann Trop Paediatr. 2002;22(4):301–311.

    Article  PubMed  Google Scholar 

  23. Hernandez-Guerrero JC, Jimenez-Farfan MD, Belmont R, Ledesma-Montes C, Baez A. Lead levels in primary teeth of children living in Mexico City. Int J Paediatr Dent. 2004;14(3):175–81.

    Article  CAS  PubMed  Google Scholar 

  24. Brown CJ, Chenery SR, Smith B, Mason C, Tomkins A, Roberts GJ, et al. Environmental influences on the trace element content of teeth-implication for disease and nutritional status. Arch Oral Biol. 2004;49(9):705–717.

    Article  CAS  PubMed  Google Scholar 

  25. Adams JB, Romdalvik J, Ramanujam VM, Legator MS. Mercury, lead, and zinc in baby teeth of children with autism versus controls. J Toxicol Environ Health. 2007;70(12):1046–1051.

    Article  CAS  Google Scholar 

  26. Al-Mahroos F, al-Saleh FS. Lead levels in deciduous teeth of children in Bahrain. Ann Trop Paediatr. 1997;17(2):147–154.

    CAS  PubMed  Google Scholar 

  27. Karahalil B, Aykanat B, Ertas N. Dental lead levels in children from two different urban and suburban areas of Turkey. Int J Hyg Environ Health. 2007;210(2):107–12.

    Article  CAS  PubMed  Google Scholar 

  28. Fischer A, Kwapulinski J, Wiechula D, Fischer T, Loska M. The occurrence of copper in deciduous teeth of girls and boys living in Upper Silesian industry region (Southern Poland). Sci Total Environ. 2008;389(2–3):315–9.

    CAS  PubMed  Google Scholar 

  29. Alomary A, Al-Momani IF, Massadeh AM. Lead and cadmium in human teeth from Jordan by atomic absorption spectrometry: Some factors influencing their concentrations. Sci Total Environ. 2006;369(1–3):69–75.

    CAS  PubMed  Google Scholar 

  30. Youravong N, Chongsuvivatwong V, Teanpaisan R, Geater AF, Dietz W, Dahlen G, et al. Morphology of enamel in primary teeth from children in Thailand exposed to environmental lead. Sci Total Environ. 2005;348(1–3):73–81.

    CAS  PubMed  Google Scholar 

  31. Gulson BL. Tooth analyses of sources and intensity of lead exposure in children. Environ Health Perspect. 1996;104(3):306–12.

    Article  CAS  PubMed  Google Scholar 

  32. Omar M, Ibrahim M, Assem H, Moustafa Y, Batgtah F. Teeth and blood lead levels in Egyptian schoolchildren: relationship to health effects. J Appl Toxicol. 2001;21(4):349–52.

    Article  CAS  PubMed  Google Scholar 

  33. Costa de Almeida GR, Pereira Saraiva Mda C, Barbosa F Jr, Krug FJ, Cury JA, de Sousa R, et al. Lead contents in the surface enamel of deciduous teeth sampled in vivo from children in uncontaminated and in lead-contaminated areas. Environ Res. 2007;104(3):337–45.

    Article  CAS  PubMed  Google Scholar 

  34. Begerow J, Freier I, Turfeld M, Kramer U, Dunemann L. Internal lead and cadmium exposure in 6-year-old children from western and eastern Germany. Int Arch Occup Environ Health. 1994;66(4):243–8.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgments

The authors, A.Sukumar and G. Nagaraj, thank Professor G.T. Bhandage, Principal, Regional Institute of Education, [NCERT], Mysore for encouragement and the facilities provided. Special thanks are owed to the sample donors of the study and Professor K. Okamoto, National Institute of Environmental Studies, Japan for supply of the CRM.

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Authors and Affiliations

  1. Zoology Section, Department of Education in Science and Mathematics, Regional Institute of Education, National Council of Educational Research and Training, Mysore, 570006, India

    G. Nagaraj & A. Sukumar

  2. JSS Dental College and Hospital, Mysore, India

    B. Nandlal

  3. Center for Environmental Studies, Anna University, Chennai, India

    S. Vellaichamy & K. Thanasekaran

  4. School of Environmental Science, Jawaharlal Nehru University, New Delhi, India

    A. L. Ramanathan

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  1. G. Nagaraj
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  2. A. Sukumar
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  3. B. Nandlal
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  4. S. Vellaichamy
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  5. K. Thanasekaran
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  6. A. L. Ramanathan
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Correspondence to A. Sukumar.

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Nagaraj, G., Sukumar, A., Nandlal, B. et al. Tooth Element Levels Indicating Exposure Profiles in Diabetic and Hypertensive Subjects from Mysore, India. Biol Trace Elem Res 131, 255–262 (2009). https://doi.org/10.1007/s12011-009-8371-4

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  • DOI: https://doi.org/10.1007/s12011-009-8371-4

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