Skip to main content
SpringerLink
Log in

Optic Nerve Head Topographic Analysis and Retinal Nerve Fiber Layer Thickness in Strabismic and Anisometropic Amblyopia

  • Original Article
  • Published:
Annals of Ophthalmology

Abstract

We compared the optic nerve head topography and retinal nerve fiber layer (RNFL) thickness of the strabismic and anisometropic amblyopic eyes with the normal fellow eyes and age-matched controls and concluded that, although amblyopia is a functional visual loss, RNFL thickness and optic nerve head topographic changes in strabismic and anisometropic amblyopic eyes may be affected by amblyopia. Further histopathological and clinic confirmations are needed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Von Noorden GK. Binocular Vision, Ocular Motility. Theory and Management of Strabismus. St Louis MO: Mosby Co, 2002, pp. 246–297.

  2. Colen TP, de Faber JT, Lemij HG. Retinal nerve fiber layer thickness in human strabismic amblyopia. Binocul Vis Strabismus 2000;15:141–146

    CAS  Google Scholar 

  3. Muller-Richter UD, Malig HJ, Schwerdtner. An enstrÅman al: three-dimensional analysis of the Heidelberg Retina Tomography. Graefes Arch Clin Exp Ophtalmol 2000;238:746–751.

  4. Itai N, Tanito M, Chihara E. Comparison of optic disc topography measured by retinal thickness analyzer with measurement by Heidelberg Retina Tomography II. Jpn J Ophtalmol 2003;47:214–220

    Article  Google Scholar 

  5. Flynn J. Amblyopia: revisited. 17th Annual Frank Costenbader Lecture. J Pediatr Ophtalmol Strabismus 1991;28:183–201

    CAS  Google Scholar 

  6. Hoyt G. Amblyopia. Br J Ophthalmol 2000;84:944–945

    Article  PubMed  CAS  Google Scholar 

  7. Von Noorden GK, Crawford ML, Levacy RA. The lateral geniculate nucleus in human anisometropic amblyopia. Invest Ophtalmol Vis Sci 1983;24:788–790

    Google Scholar 

  8. Von Noorden GK, Crawford MLJ. The lateral geniculate nucleus in human strabismic amblyopia. Invest Ophtalmol Vis Sci 1992;33:2729–2732

    Google Scholar 

  9. Ikeda H, Tremain KE. Amblyopia occurs in retinal ganglion cells in cats reared with convergent squint without alternation fixation. Exp Brain Res 1979;35:559–582

    Article  PubMed  CAS  Google Scholar 

  10. Chino YM, Shansky MS, Homasaki DI. Development of receptive field properties of retinal ganglion cells in kittens raised with a convergent squint. Exp Brain Res 1980;39:313–320

    Article  PubMed  CAS  Google Scholar 

  11. Cleland BG, Crewther DB, Crewther SG, et al. Normality of spatial resolution of ganglion cells in cats with strabismic amblyopia. J Physiol 1982;326:235–249

    PubMed  CAS  Google Scholar 

  12. Yen MY, Cheng CY, Wang AG. Retinal nerve fiber layer thickness in unilateral amblyopia. Invest Ophtalmol Vis Sci 2004;45:141–146

    Google Scholar 

  13. Colen TP, de Faber JT, Iemij HG. Retinal nerve fiber layer thickness in human strabismic amblyopia. Binocul Vis Strabismus Q 2000;15:141–146

    PubMed  CAS  Google Scholar 

  14. Bozkurt B, Irkeá M, Orhan M, et al. Thickness of the retinal nerve fiber layer in patients with anisometropic and strabismic amblyopia. Strabismus 2003;II:1–7

    Article  Google Scholar 

  15. Lempert P. Optic nerve hypoplasia and small eyes in presumed amblyopia. JAAPOS 2000;4:258–266

    CAS  Google Scholar 

  16. Baloszi AG, Rootman J, Drance SM, et al. The effect of age on the nerve fiber population of the human optic nerve. Am J Ophtalmol 1984;97:760–766

    Google Scholar 

  17. Jonas JB, Schmidt AM, Muller Bergh JA, et al. Human optic nerve fiber count and optic disc size. Invest Ophtalmol Vis Sci 1992;33:2012–2018

    CAS  Google Scholar 

  18. Boddini-Caramelli C, Hotonaka M, Polati M, et al. Thickness of the retinal nerve fiber layer in amblyopic and normal eyes: a scanning laser polarimetry study. JAAPOS 2001;5:82–84

    Google Scholar 

Download references

Acknowledgement

This study was supported by the Research Project Unit of Akdeniz University.

Author information

Authors and Affiliations

  1. Department of Ophthalmology, Akdeniz University School of Medicine, Antalya, Turkey

    Yasar Duranoglu MD

  2. Zümrütova Mah. Sinanoglu Cad., Bingöl Apt. No=89/19, 07160, Antalya, Turkey

    Yasar Duranoglu MD

Authors
  1. Yasar Duranoglu MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yasar Duranoglu MD.

Additional information

Dr. Duranoglu is from the Department of Ophthalmology, Akdeniz University School of Medicine, Antalya, Turkey.

The authors have stated that they do not have a significant financial interest or other relationship with any product manufacturer or provider of services discussed in this article. The authors do not discuss the use of off-label products, which includes unlabeled, unapproved, or investigative products or devices.

The authors determined that retinal nerve fiber layer thickness and optic nerve head topographic changes in strabismic and anisometropic amblyopic eyes may be affected by amblyopia.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Duranoglu, Y. Optic Nerve Head Topographic Analysis and Retinal Nerve Fiber Layer Thickness in Strabismic and Anisometropic Amblyopia. Ann Ophthalmol 39, 291–295 (2007). https://doi.org/10.1007/s12009-007-9014-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12009-007-9014-z

Keywords

Search

Navigation