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Behavior Therapy for Tourette Syndrome: A Systematic Review and Meta-analysis

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Opinion statement

When tics caused by Tourette Syndrome cause meaningful impairment for patients, a comprehensive treatment approach includes education of patients, peers, and family, treatment of comorbid behavioral disorders if present, and consideration of behavior therapy and pharmacotherapy for tics themselves. This systematic review and meta-analysis demonstrates that behavior therapies based on Habit Reversal Therapy, including the Comprehensive Behavioral Intervention for Tics are effective in reducing tic severity when compared with supportive psychotherapy. When these behavior therapies are unavailable, Exposure with Response Prevention may also be effective. Both face-to-face and telehealth delivery methods for behavior therapy improve tic severity, and broader distribution of behavior therapy through increased training or telehealth methods is encouraged. High-quality randomized trials comparing behavior therapies for tics with pharmacotherapy are needed.

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  1. Kurlan R. Clinical practice. Tourette’s Syndrome N Engl J Med. 2010;363(24):2332–8.

    Article  CAS  Google Scholar 

  2. American Psychiatric Association. Diagnostic and statistical manual of mental disorders : DSM-IV-TR. Washington D.C: Amercian Psychiatric Association. 2003.

  3. Price R, Kidd KK, Cohen DJ, Pauls DL, Leckman JF. A twin study of Tourette syndrome. Arch Gen Psychiatry. 1985;42(8):815–20.

    Article  PubMed  CAS  Google Scholar 

  4. Kurlan R, Eapen V, Stern J, McDermott MP, Robertson MM. Bilineal transmission in Tourette’s syndrome families. Neurology. 1994;44(12):2336.

    Article  PubMed  CAS  Google Scholar 

  5. McNaught KS, Mink JW. Advances in understanding and treatment of Tourette syndrome. Nat Rev Neurol. 2011;7(12):667–76.

    Article  PubMed  CAS  Google Scholar 

  6. Singer HS. Treatment of tics and tourette syndrome. Curr Treat Options Neurol. 2010;12(6):539–61.

    Article  PubMed  Google Scholar 

  7. Franklin SA, Walther MR, Woods DW. Behavioral interventions for tic disorders. Psychiatr Clin N Am. 2010;33(3):641–55.

    Article  Google Scholar 

  8. O’Connor KP, Laverdure A, Taillon A, Stip E, Borgeat F, Lavoie M. Cognitive behavioral management of Tourette’s syndrome and chronic tic disorder in medicated and unmedicated samples. Behav Res Ther. 2009;47(12):1090–5.

    Article  PubMed  Google Scholar 

  9. Himle MB, Woods DW, Piacentini JC, Walkup JT. Brief review of habit reversal training for Tourette syndrome. J Child Neurology. 2006;21(8):719–25.

    Article  Google Scholar 

  10. Azrin NH, Nunn RG. Habit-reversal: a method of eliminating nervous habits and tics. Behav Res Ther. 1973;11(4):619–28.

    Article  PubMed  CAS  Google Scholar 

  11. Peterson AL, Azrin NH. An evaluation of behavioral treatments for Tourette syndrome. Behav Res Ther. 1992;30(2):167–74.

    Article  PubMed  CAS  Google Scholar 

  12. van de Griendt JM, Verdellen CW, van Dijk MK, Verbraak MJ. Behavioral treatment of tics: habit reversal and exposure with response prevention. Neuroscience and Biobehavioral Rev. 2012. doi:10.1016/j.neubiorev.2012.10.007. Summarizes the history, evidence, and methods of delivery for HRT and ERP. The authors provide useful guiding comments about situations in which either therapy might be preferred and about the place of behavior therapies as part of an overall treatment strategy for TS.

    Google Scholar 

  13. Wilhelm S, Peterson AL, Piacentini J, Woods DW, Deckersbach T, Sukhodolsky DG, et al. Randomized trial of behavior therapy for adults with Tourette syndrome. Arch Gen Psychiatry. 2012;69(8):795–803. A high quality randomized controlled trial demonstrating the efficacy of CBIT compared with supportive psychotherapy in reducing tic severity in adults..

    Article  PubMed  Google Scholar 

  14. Piacentini J, Woods DW, Scahill L, Wilhelm S, Peterson AL, Chang S, et al. Behavior therapy for children with Tourette disorder: a randomized controlled trial. JAMA. 2010;303(19):1929–37. A high quality randomized controlled trial demonstrating the efficacy of CBIT compared with supportive psychotherapy in reducing tic severity in children..

    Article  PubMed  CAS  Google Scholar 

  15. Cook CR, Blacher J. Evidence-based psychosocial treatments for tic disorders. Clin Psychology: Science and Practice. 2007;14(3):252–67.

    Article  Google Scholar 

  16. Bate KS, Malouff JM, Thorsteinsson ET, Bhullar N. The efficacy of habit reversal therapy for tics, habit disorders, and stuttering: a meta-analytic review. Clin Psychology Rev. 2011;31(5):865–71. A detailed review with calculated effect sizes for various behavior therapies compared with their comparator treatments, summarized in a useful table. Provides comments about these therapies for body-focused habit disorders other than TS.

    Article  Google Scholar 

  17. Frank M, Cavanna AE. Behavioral treatments for Tourette syndrome: An evidence-based review. Behav Neurology. 2012. A recent detailed summary of published data on a variety of behavior therapies vs comparison treatments and in case reports / case series. A summary table provides a useful reference of these sources.

  18. Verdellen C, van de Griendt J, Hartmann A, Murphy T, Group EG. European clinical guidelines for Tourette syndrome and other tic disorders. Part III: behavioral and psychosocial interventions. Eur Child Adolesc Psychiatry. 2011;20(4):197–207.

    Article  PubMed  Google Scholar 

  19. Steeves T, McKinlay BD, Gorman D, Billinghurst L, Day L, Carroll A, et al. Canadian guidelines for the evidence-based treatment of tic disorders: behavioral therapy, deep brain stimulation, and transcranial magnetic stimulation. Can J Psychiatry. 2012;57(3):144–51.

    PubMed  Google Scholar 

  20. Storch EA, Murphy TK, Geffken GR, Sajid M, Allen P, Roberti JW, et al. Reliability and validity of the Yale Global Tic Severity Scale. Psychological Assess. 2005;17(4):486–91.

    Article  Google Scholar 

  21. Storch EA, De Nadai AS, Lewin AB, McGuire JF, Jones AM, Mutch PJ, et al. Defining treatment response in pediatric tic disorders: a signal detection analysis of the Yale Global Tic Severity Scale. J Child Adolesc Psychopharmacol. 2011;21(6):621–7.

    Article  PubMed  Google Scholar 

  22. Harris RP, Helfand M, Woolf SH, Lohr KN, Mulrow CD, Teutsch SM, et al. Current methods of the US Preventive Services Task Force: a review of the process. Am J Prev Med. 2001;20(3 Suppl):21–35.

    Article  PubMed  CAS  Google Scholar 

  23. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.

    Article  PubMed  Google Scholar 

  24. Wilhelm S, Deckersbach T, Coffey BJ, Bohne A, Peterson AL, Baer L. Habit reversal vs supportive psychotherapy for Tourette’s disorder: a randomized controlled trial. Am J Psychiatry. 2003;160(6):1175–7.

    Article  PubMed  Google Scholar 

  25. Deckersbach T, Rauch S, Buhlmann U, Wilhelm S. Habit reversal vs supportive psychotherapy in Tourette’s disorder: a randomized controlled trial and predictors of treatment response. Behav Res Ther. 2006;44(8):1079–90.

    Article  PubMed  Google Scholar 

  26. Verdellen CW, Keijsers GP, Cath DC, Hoogduin CA. Exposure with response prevention vs habit reversal in Tourettes’s syndrome: a controlled study. Behav Res Ther. 2004;42(5):501–11.

    Article  PubMed  Google Scholar 

  27. Himle MB, Freitag M, Walther M, Franklin SA, Ely L, Woods DW. A randomized pilot trial comparing videoconference vs face-to-face delivery of behavior therapy for childhood tic disorders. Behav Res Ther. 2012;50(9):565–70. A randomized trial that shows improvement in tic severity in groups assigned to both face-to-face and videoconference delivered CBIT in a within subjects baseline / post-treatment analysis.

    Article  PubMed  Google Scholar 

  28. Azrin NH, Peterson AL. Treatment of Tourette syndrome by habit reversal: a waiting-list control group comparison. Behav Ther. 1990;21(3):305–18.

    Article  Google Scholar 

  29. Woods DW, Piacentini JC, Scahill L, Peterson AL, Wilhelm S, Chang S, et al. Behavior therapy for tics in children: acute and long-term effects on psychiatric and psychosocial functioning. J Child Neurology. 2011;26(7):858–65. This study reports psychiatric and psychosocial secondary outcomes from a large randomized trial of CBIT in children.

    Article  Google Scholar 

  30. de Bruijn S, Verdellen C, Cath D, Verbraak M, Wertenbroek A, van de Griendt J, et al. Risperidone vs behavior therapy in the treatment of tic disorders – a randomized single-blinded trial. Parkinsonism Rel Disord. 2012;18:S61–2.

    Article  Google Scholar 

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Daryl J. Wile declares that he has no conflict of interest.

Tamara M. Pringsheim declares that she has no conflict of interest.

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Correspondence to Tamara M. Pringsheim MD, MSc.

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Wile, D.J., Pringsheim, T.M. Behavior Therapy for Tourette Syndrome: A Systematic Review and Meta-analysis. Curr Treat Options Neurol 15, 385–395 (2013). https://doi.org/10.1007/s11940-013-0238-5

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