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Kidney Stone Risk Following Modern Bariatric Surgery

  • Minimally Invasive Surgery (V Bird and M Desai, Section Editors)
  • Published:
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Abstract

Over the past 10 years, a variety of reports have linked bariatric surgery to metabolic changes that alter kidney stone risk. Most of these studies were retrospective, lacked appropriate controls, or involved bariatric patients with a variety of inclusion criteria. Despite these limitations, recent clinical and experimental research has contributed to our understanding of the pathophysiology of stone disease in this high-risk population. This review summarizes the urinary chemistry profiles that may be responsible for the increased kidney stone incidence seen in contemporary epidemiological bariatric studies, outlines the mechanisms of hyperoxaluria and potential therapies through a newly described experimental bariatric animal model, and provides a focused appraisal of recommendations for reducing stone risk in bariatric stone formers.

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Conflict of Interest

Dr. Ricardo D. Gonzalez declares no potential conflicts of interest relevant to this article.

Dr. Benjamin K. Canales received funding from National Institutes of Health (NIH K08 DK089000-04), AUA Foundation Rising Star in Urology Research Award, Astellas Global Development, Inc., and Ethicon Endo-Surgery.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

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Authors and Affiliations

  1. Department of Urology, University of South Florida, Tampa, FL, USA

    Ricardo D. Gonzalez

  2. Department of Urology, University of Florida, Gainesville, FL, USA

    Benjamin K. Canales

  3. Department of Urology, 1600 SW Archer Rd, Rm N-213, PO Box 100247, Gainesville, FL, 32610, USA

    Benjamin K. Canales

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  1. Ricardo D. Gonzalez
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  2. Benjamin K. Canales
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Correspondence to Benjamin K. Canales.

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This article is part of the Topical Collection on Minimally Invasive Surgery

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Gonzalez, R.D., Canales, B.K. Kidney Stone Risk Following Modern Bariatric Surgery. Curr Urol Rep 15, 401 (2014). https://doi.org/10.1007/s11934-014-0401-x

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  • DOI: https://doi.org/10.1007/s11934-014-0401-x

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