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Deadly Public Policy: What the Future Could Hold for the HIV Epidemic among Injection Drug Users in Vancouver

  • Behavioral Aspects of HIV Management (RJ DiClemente and JL Brown, Section Editors)
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Abstract

The scope and scale of the HIV outbreak that occurred among injection drug users in Vancouver in the late 1990s was unprecedented and resulted in some 2,000 new HIV infections, with incidence rates reaching 18 per 100 person-years. This outbreak, localized mainly in one neighbourhood, cost the Canadian health care system more than 1 billion dollars to diagnose, care and treat. A number of factors combined to stabilize HIV incidence: 1) HIV prevalence became saturated among those at highest risk; 2) several public health policies focused on drug users were implemented, including increased and additional decentralized needle exchange programs, expanded methadone maintenance services, better addiction treatment services, improved housing, and mental health programs; and 3) increased access and expansion of Highly Active Antiretroviral Therapy. To ensure that a similar outbreak never occurs again in Vancouver and other cities, future health policy must consider the political, psychosocial and socioeconomic factors that contributed to this outbreak. These policies must address the unintended adverse consequences of past policies and their repercussions for marginalized individuals living in this community and beyond.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

  1. Patrick DM, Strathdee SA, Archibald CP, et al. Determinants of HIV seroconversion in injection drug users during a period of rising prevalence in Vancouver. Int J STD AIDS. 1997;8(7):437–45.

    Article  PubMed  CAS  Google Scholar 

  2. Schechter MT, Strathdee SA, Cornelisse PG, et al. Do needle exchange programmes increase the spread of HIV among injection drug users?: an investigation of the Vancouver outbreak. AIDS. 1999;13(6):F45–51.

    Article  PubMed  CAS  Google Scholar 

  3. Spittal PM, Craib KJ, Wood E, et al. Risk factors for elevated HIV incidence rates among female injection drug users in Vancouver. CMAJ. 2002;166(7):894–9.

    PubMed  Google Scholar 

  4. Spittal PM, Small W, Wood E, et al. How otherwise dedicated AIDS prevention workers come to support state-sponsored shortage of clean syringes in Vancouver, Canada. Int J Drug Pol. 2003;15:36–45.

    Article  Google Scholar 

  5. •• Strathdee SA, Patrick DM, Currie SL, et al. Needle exchange is not enough: lessons from the Vancouver injecting drug use study. AIDS. 1997;11(8):F59–65. A seminal paper that demonstrated that whereas needle exchange program were crucial for sterile syringe provision, they should be considered one component of a comprehensive programme including counselling, support and education.

    Article  PubMed  CAS  Google Scholar 

  6. Wood E, Kerr T, Spittal PM, et al. The potential public health and community impacts of safer injecting facilities: evidence from a cohort of injection drug users. J Acquir Immune Defic Syndr. 2003;32(1):2–8.

    Article  PubMed  Google Scholar 

  7. Wood E, Kerr T. What to do when you hit rock bottom? responding to drugs in the city of Vancouver. Int J Drug Pol. 2006;17:55–60.

    Article  Google Scholar 

  8. Angelotta C, McKoy JM, Fisher MJ, et al. Legal, financial, and public health consequences of transfusion transmitted hepatitis C virus in persons with haemophilia. Vox Sang. 2007;93(2):159–65.

    Article  PubMed  CAS  Google Scholar 

  9. Dunn K. HIV and Canada’s hemophiliacs: looking back at a tragedy. CMAJ. 1993;148(4):609–12.

    PubMed  CAS  Google Scholar 

  10. Raboud JM, Boily MC, Rajeswaran J, et al. The impact of needle-exchange programs on the spread of HIV among injection drug users: a simulation study. J Urban Health. 2003;80(2):302–20.

    Article  PubMed  CAS  Google Scholar 

  11. Craib KJ, Spittal PM, Wood E, et al. Risk factors for elevated HIV incidence among Aboriginal injection drug users in Vancouver. CMAJ. 2003;168(1):19–24.

    PubMed  Google Scholar 

  12. Miller CL, Wood E, Spittal PM, et al. The future face of coinfection: prevalence and incidence of HIV and hepatitis C virus coinfection among young injection drug users. J Acquir Immune Defic Syndr. 2004;36(2):743–9.

    Article  PubMed  Google Scholar 

  13. West GR, Corneli AL, Best K, et al. Focusing HIV prevention on those most likely to transmit the virus. AIDS Educ Prev. 2007;19(4):275–88.

    Article  PubMed  Google Scholar 

  14. Corneil TA, Kuyper LM, Shoveller J, et al. Unstable housing, associated risk behaviour, and increased risk for HIV infection among injection drug users. Health Place. 2006;12(1):79–85.

    Article  PubMed  Google Scholar 

  15. Shannon K, Ishida T, Lai C, et al. The impact of unregulated single room occupancy hotels on the health status of illicit drug users in Vancouver. Int J Drug Pol. 2006;17:107–14.

    Article  Google Scholar 

  16. Hermans P. Current review and clinical management of patients with primary HIV-1 infection: limits and perspectives. Biomed Pharmacother. 2001;55(6):301–7.

    Article  PubMed  CAS  Google Scholar 

  17. Tyndall MW, Currie S, Spittal P, et al. Intensive injection cocaine use as the primary risk factor in the Vancouver HIV-1 epidemic. AIDS. 2003;17(6):887–93.

    Article  PubMed  Google Scholar 

  18. Wood E, Lloyd-Smith E, Li K, et al. Frequent needle exchange use and HIV incidence in Vancouver, Canada. Am J Med. 2007;120(2):172–9.

    Article  PubMed  Google Scholar 

  19. •• Wood E, Kerr T, Marshall BDL, Li K, Zhang R, Hogg RS, Harrigan PR, Montaner JSG. Longitudinal community plasma HIV-1 RNA levels and HIV-1 incidence among injection drug users. BMJ. 2009;338:b1649. This paper shows that a longitudinal measure of community plasma HIV-1 RNA concentration in Vancouver Downtown Eastside was correlated with the HIV incidence rate and predicted HIV incidence independent of unsafe sexual behaviors and sharing used syringes.

    Article  PubMed  Google Scholar 

  20. Vlahov D, Celentano DD. Access to highly active antiretroviral therapy for injection drug users: adherence, resistance, and death. Cad Saude Publica. 2006;22(4):705–18.

    Article  PubMed  Google Scholar 

  21. Wood E, Tyndall MW, Qui Z, Zhang R, Montaner JSG, Kerr T. Service uptake and characteristics of injection drug users utilizing North America’s first medically supervised safer injecting facility. Am J Public Health. 2006;96(5):770–3.

    Article  PubMed  Google Scholar 

  22. Supervised Injection Site. Research: user statistics. Website: http://supervisedinjection.vch.ca/research/supporting_research/user_statistics Accessed: April 23, 2012.

  23. Wood E, Kerr T, Small W, et al. Changes in public order after the opening of a medically supervised safer injecting facility for illicit injection drug users. Can Med Assoc J. 2004

  24. Stoltz JA, Wood E, Small W, et al. Changes in injecting practices associated with the use of a medically supervised safer injection facility. J Public Health. 2007;29(1):35–9.

    Article  Google Scholar 

  25. Milloy M-J, Kerr T, Tyndall M, et al. Estimated drug overdose deaths averted by North America’s first medically-supervised safer injection facility. PLoS One. 2008;3(10):e3351.

    Article  PubMed  Google Scholar 

  26. Wood E, Tyndall MW, Zhang R, et al. Attendance at supervised injecting facilities and use of detoxification services. N Engl J Med. 2006;354(23):2512–4. PubMed171(7): 731–734.

    Article  PubMed  CAS  Google Scholar 

  27. Oviedo-Joekes E, Nosyk B, Brissette S, et al. The North American Opiate Medication Initiative (NAOMI): profile of participants in North America’s first trial of heroin-assisted treatment. Eur J Epidemiol. 2006;21(7):545–9.

    Article  Google Scholar 

  28. Oviedo-Joekes E, Brissette S, Marsh DC, et al. Diacetylmorphine versus methadone for the treatment of opioid addiction. N Engl J Med. 2009 Aug 20;361(8):777–86

  29. Supreme Court of Canada. Canada (Attorney General) v. PHS Community Services Society, 2011 SCC 44, [2011] 3 S.C.R. 134. Docket: 3356, Date: September 30, 2011.

  30. Globe and Mail. Harper Tories endorse heroin research project. Published Wednesday, Oct. 12, 2011 9:47PM EDT Website: http://www.theglobeandmail.com/news/national/british-columbia/harper-tories-endorse-heroin-research-project/article2199476/. Accessed: April 23, 2012.

  31. Fuller CM, Vlahov D, Arria AM, et al. Factors associated with adolescent initiation of injection drug use. Public Health Rep. 2001;116 Suppl 1:136–45.

    Article  PubMed  Google Scholar 

  32. Quinn TC, Wawer MJ, Sewankambo N, et al. Viral load and heterosexual transmission of human immunodeficiency virus type 1. Rakai Project Study Group. N Engl J Med. 2000;342(13):921–9.

    Article  PubMed  CAS  Google Scholar 

  33. Wood E, Kerr T, Palepu A, et al. Slower uptake of HIV antiretroviral therapy among Aboriginal injection drug users. J Infect. 2006;52(4):233–6.

    Article  PubMed  Google Scholar 

  34. Strathdee SA, Palepu A, Cornelisse PG, et al. Barriers to use of free antiretroviral therapy in injection drug users. JAMA. 1998;280(6):547–9.

    Article  PubMed  CAS  Google Scholar 

  35. • Montaner JS, Hogg R, Wood E, et al. The case for expanding access to highly active antiretroviral therapy to curb the growth of the HIV epidemic. Lancet. 2006;368:531–6. Commentary showing the role that HAART has in reducing spread of the HIV/AIDS pandemic.

    Article  PubMed  Google Scholar 

  36. Kerr T, Oleson M, Tyndall MW, et al. A description of a peer-run supervised injection site for injection drug users. J Urban Health. 2005;82(2):267–75.

    Article  PubMed  Google Scholar 

  37. Braitstein P, Li K, Tyndall M, et al. Sexual violence among a cohort of injection drug users. Soc Sci Med. 2003;57(3):561–9.

    Article  PubMed  Google Scholar 

  38. Small D, Palepu A, Tyndall MW, et al. The establishment of North America’s first state sanctioned supervised injection facility: a case study in culture change. Int J Drug Pol. 2006;17:73.

    Article  Google Scholar 

  39. Wood E, Tyndall MW, Spittal PM, et al. Unsafe injection practices in a cohort of injection drug users in Vancouver: could safer injecting rooms help? CMAJ. 2001;165(4):405–10.

    PubMed  CAS  Google Scholar 

  40. Wood E, Tyndall MW, Spittal PM, et al. Needle exchange and difficulty with needles access during an ongoing HIV epidemic. Int J Drug Pol. 2002;13:95–102.

    Article  Google Scholar 

  41. Wood E, Montaner JS, Tyndall MW, Schechter MT, et al. Prevalence and correlates of untreated human immunodeficiency virus type 1 infection among persons who have died in the era of modern antiretroviral therapy. J Infect Dis. 2003;188(8):1164–70.

    Article  PubMed  Google Scholar 

  42. STOP HIV/AIDS. Website; http://www.cfenet.ubc.ca/our-work/programs/stop-hiv-aids. Accessed: April 23, 2012.

  43. Montaner JSG, Lima VD, Barrios R, Yip B, Wood E, Kerr T, Shannon K, Harrigan R, Hogg RS, Daly P, Kendall P. Association of highly active antiretroviral therapy coverage, population viral load, and yearly new HIV diagnoses in British Columbia, Canada: a population-based study The Lancet. Lancet. 2010;376:532–9.

    Article  PubMed  Google Scholar 

  44. Montaner JSG. Treatment as prevention—a double hat trick. Lancet. 2011;378:208–9.

    Article  PubMed  Google Scholar 

  45. • Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493–505. This clinical trial demonstrates that the early initiation of HAART reduced rates of sexual transmission of HIV and related clinical events, indicating both personal and public health benefits from such therapy.

    Article  PubMed  CAS  Google Scholar 

  46. McGovern BH. Hepatitis C in the HIV-infected patient. J Acquir Immune Defic Syndr. 2007;45 Suppl 2:S47–56.

    PubMed  Google Scholar 

  47. Marshall BDL, Wood E, Zhang R, et al. Condom use among injection drug users accessing supervised injection facility. Sex Transm Infect. 2008. doi:10.1136/sti.2008.

  48. Shannon K, Rusch M, Shoveller J, et al. Mapping violence and policing as an environmental-structural barrier to health service and syringe availability among substance-using women in street-level sex work. Int J Drug Pol. 2008;19(2):140–7.

    Article  CAS  Google Scholar 

  49. Miller C, Schechter M, Wood E, et al. The potential health and economic impact of implementing a medically prescribed heroin program among Canadian injection drug users. Int J Drug Pol. 2004;15(4):259–63.

    Article  Google Scholar 

  50. Gerlich M, Gschwend P, Uchtenhagen A, et al. Prevalence of hepatitis and HIV infections and vaccination rates in patients entering the heroin-assisted treatment in Switzerland between 1994 and 2002. Eur J Epidemiol. 2006;21(7):545–9.

    Article  PubMed  Google Scholar 

  51. McInnes CW, Druyts E, Harvard SS, et al. HIV/AIDS in Vancouver, British Columbia: a growing epidemic. Harm Reduction J. 2009;6:5.

    Article  Google Scholar 

  52. Wood E, Spittal P, Li K, et al. Inability to access addiction treatment and risk of HIV infection among injection drug users. J Acquir Immune Defic Syndr. 2004;36(2):750–4.

    Article  PubMed  Google Scholar 

  53. Willner-Reid J, Belendiuk KA, Epstein DH, et al. Hepatitis C and HIV risk behaviors in polydrug users on methadone maintenance. J Subst Abuse Treat. 2007.

  54. Grebely J, Genoway KA, Raffa JD, et al. Barriers associated with the treatment of hepatitis C virus infection among illicit drug users. Drug Alcohol Depend. 2007.

  55. Wilson DP, Law MG, Grulich AE, et al. Relation between HIV viral load and infectiousness: a model-based analysis. Lancet. 2008;372(9635):314–20.

    Article  PubMed  Google Scholar 

  56. Cheryl Chan, Rich Coleman promises a Downtown Eastside czar. The Province. Friday, February 06, 2009. http://www2.canada.com/theprovince/news/story.html?id=97182a66-f2b8-4bdc-a9dd-80aa4581cc83. Accessed April 23, 2012.

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Acknowledgments

We would like to acknowledge and honor the memory of John Turvey, who helped in establishing the first needle exchange in Vancouver, and the many women who were murdered in the Downtown Eastside.

Disclosures

M. O’Shaughnessy: consultant to Saint Paul’s Hospital; R. Hogg: none; S. A. Strathdee: none; J. S. G. Montaner: none.

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Correspondence to Robert S. Hogg.

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O’Shaughnessy, M.V., Hogg, R.S., Strathdee, S.A. et al. Deadly Public Policy: What the Future Could Hold for the HIV Epidemic among Injection Drug Users in Vancouver. Curr HIV/AIDS Rep 9, 394–400 (2012). https://doi.org/10.1007/s11904-012-0130-z

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  • DOI: https://doi.org/10.1007/s11904-012-0130-z

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