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Hylotelephium telephium Flower Extract-Mediated Biosynthesis of CuO and ZnO Nanoparticles with Promising Antioxidant and Antibacterial Properties for Healthcare Applications

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Abstract

The present work mainly concentrates on the biosynthesis of copper oxide (CuO) nanoparticles (NPs) and zinc oxide (ZnO) nanoparticles using Hylotelephium telephium subsp. telephium flower extract. XRD study confirms the formation of monoclinic CuO NPs and hexagonal ZnO NPs. SEM and TEM analyses show that the CuO NPs were spherical in shape of 83 nm in size, whereas the ZnO NPs were irregular in shape of 36 nm in size. The synthesized nanoparticles have excellent antioxidant and antibacterial activities. The antioxidant activity results reveal that the synthesized nanoparticles exhibit excellent free radicals scavenging activity. A comparative study on the antibacterial activity of the chemically synthesized nanoparticles and biosynthesized nanoparticles was conducted and it was found that the biosynthesized nanoparticles possess better activities than the chemically synthesized nanoparticles. Hence, biosynthesis is a more advantageous and reliable method when compared to chemical synthesis for the production of nanoparticles for antibacterial applications.

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Acknowledgements

The work was carried out with financial support from the Ministry of Education and Science of the Russian Federation in the framework of increase Competitiveness Program of NUST “MISIS”, implemented by a governmental decree dated 16th of March 2013, N 211. This research was supported by the Korean Research Fellowship program funded by the Ministry of Science and ICT through the National Research Foundation of Korea (KRF Grant No. 2018H1D3A1A01037054). Authors also acknowledge support under the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education (NRF-2019R1I1A1A01062458).

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Authors and Affiliations

  1. Department of Fine Chemistry, Biosensor Research Institute, Seoul National University of Science and Technology (Seoul Tech), Gongneung-ro 232, Nowon-gu, Seoul, 01811, Republic of Korea

    Gopalu Karunakaran

  2. Department of Functional Nanosystems and High-Temperature Materials, National University of Science and Technology “MISiS”, Leninskiy Pr. 4, Moscow, Russia, 119049

    Gopalu Karunakaran & Evgeny Kolesnikov

  3. Department of Bio-chemistry/Bio-technology/Bio-informatics, Avinashilingam Institute for Home Science and Higher Education for Women, Mettupalayam Road, Bharathi Park Road, Coimbatore, 641 043, India

    Matheswaran Jagathambal

  4. Department of Physics, K. S. Rangasamy College of Arts and Science (Autonomous), Tiruchengode, Tamil Nadu, 637215, India

    Govindan Suresh Kumar

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  1. Gopalu Karunakaran
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  2. Matheswaran Jagathambal
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Correspondence to Gopalu Karunakaran.

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Karunakaran, G., Jagathambal, M., Kumar, G.S. et al. Hylotelephium telephium Flower Extract-Mediated Biosynthesis of CuO and ZnO Nanoparticles with Promising Antioxidant and Antibacterial Properties for Healthcare Applications. JOM 72, 1264–1272 (2020). https://doi.org/10.1007/s11837-020-04007-9

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