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Hip fracture in three elderly populations of central Spain: data from the NEDICES study

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Abstract

There is a paucity of data concerning the specific associations between hip fracture in the elderly and other age-related conditions, as well as its impact on long-term survival. This study was aimed to estimate the prevalence, risk factors, and outcome of self-reported hip fracture (srHF) in a cohort of Spanish elderly individuals. Neurological Disorders in Central Spain (NEDICES) is a census population-based survey of the prevalence and incidence of major age-associated conditions in three areas of central Spain. Data on health status and several chronic conditions were evaluated in the baseline questionnaire (1994–1995). Odds ratios for the association between srHF and other comorbidities and health-related variables were assessed by logistic regression. A Cox model estimated the impact of srHF on 13-year all-cause mortality. The final cohort comprised 5,278 community-living elderly subjects. A total of 166 participants (3.1%) had srHF. Prevalence was associated with higher age, female gender, degree of urbanisation of residence place, lower body mass index (BMI), higher number of chronic medications, higher Pfeffer FAQ score, being unmarried (P < 0.001 for all), and infantile living conditions (P = 0.007). Participants with srHF had a higher number of associated chronic conditions (P < 0.001). In the multivariate analysis, self-reported osteoporosis, lower BMI category, rural environment during childhood, and higher age were identified as independent risk factors for srHF. Adjusted hazard ratio for mortality in the srHF group was 1.40 (95% confidence interval 1.15–1.71; P = 0.001). srHF is a common condition among community-living elderly population in Spain, and has a significant impact upon long-term all-cause mortality.

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Acknowledgments

A complete list of the investigators and advisors of the NEDICES Study Group is exposed in http://www.ciberned.es and http://www.neurologia12o.com. We also thank Joseph Healey for the review of the English manuscript. This work was partly supported by the Fundación Mutua Madrileña [2006–9]; the Spanish Health Research Agency [FIS 93/0773]; the Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED); and the National Institutes of Health [NIH R01 NS039422 to J.B.L and F.B.P.].

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Authors and Affiliations

  1. Department of Internal Medicine, Hospital Universitario “12 de Octubre”, Universidad Complutense, Avda.de Córdoba, s/n, 28041, Madrid, Spain

    Mario Fernández-Ruiz & Juan Manuel Guerra-Vales

  2. Department of Neurology, Hospital Universitario “12 de Octubre”, Universidad Complutense, Madrid, Spain

    Rocío Trincado, Julián Benito-León & Félix Bermejo-Pareja

  3. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid, Spain

    Rocío Trincado, Julián Benito-León & Félix Bermejo-Pareja

  4. National Centre for Epidemiology, Instituto de Salud Carlos III, Madrid, Spain

    María José Medrano

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  1. Mario Fernández-Ruiz
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  2. Juan Manuel Guerra-Vales
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  3. Rocío Trincado
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  5. Julián Benito-León
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Correspondence to Mario Fernández-Ruiz.

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Fernández-Ruiz, M., Guerra-Vales, J.M., Trincado, R. et al. Hip fracture in three elderly populations of central Spain: data from the NEDICES study. Intern Emerg Med 9, 33–41 (2014). https://doi.org/10.1007/s11739-011-0728-y

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