Abstract
Objective
To observe the clinical effect of moxibustion on Governor Vessel for ankylosing spondylitis (AS) due to kidney yang deficiency.
Methods
A total of 60 patients of AS due to kidney yang deficiency were randomly divided into a treatment group and a control group by random digital table, 30 cases in each group. Both of the two groups were treated by oral administration of Sulfasalazine tablets. Additionally, the treatment group was given moxibustion on Governor Vessel, and the control group was given sham moxibustion. The treatment was given once every other day, 4 weeks constituted one course, 2 courses in total. Before treatment, after 1-course and 2-course treatments, the quantified scores of traditional Chinese medicine (TCM) syndromes and the symptoms scores recommended by AS International Society [including Bath ankylosing spondylitis disease activity index (BASDAI), visual analogue scale (VAS), Bath ankylosing spondylitis functional index (BASFI) and Bath ankylosing spondylitis metrology index (BASMI)] were respectively observed and recorded, and the change of safety item was monitored.
Results
After 1-course and 2-course treatments, the quantified scores of TCM syndromes were obviously improved than those before treatment in the two groups (P<0.05), and the score was improved better in the treatment group than that in the control group (P<0.05). In comparison within the group, there were no statistical differences between the scores after 1-course treatment and 2-course treatment in the two groups (P>0.05). After 1-course treatment, the items of the symptoms scores were improved than those before treatment in the two groups (P<0.05). After 2-course treatment, the therapeutic effect was more remarkable in the treatment group, with a statistical difference between the two groups (P<0.05). During treatment, no obvious abnormality in all safety items was noticed in the two groups.
Conclusion
Moxibustion on Governor Vessel can effectively relieve the clinical symptoms of AS patients, without obvious adverse reaction.
摘要
目的
观察督灸治疗肾阳亏虚型强直性脊柱炎(ankylosing spondylitis, AS)的临床疗效。
方法
将60 例活 动性肾阳亏虚型AS 患者按随机数字表随机分为治疗组和对照组, 每组30 例。两组均予口服柳氮磺吡啶片治疗, 治疗组在此基础上予督灸, 对照组予安慰灸。隔天治疗1 次, 4 星期为1 个疗程, 共治疗2 个疗程。分别于治疗前、 治疗1 个和2 个疗程后观察并记录中医证候量化积分和国际AS 评价组推荐的症状积分[包括Bath 强直性脊柱炎 疾病活动性指数(Bath ankylosing spondylitis disease activity index, BASDAI)量表、疼痛视觉模拟量表(visual analogue scale, VAS)评分、Bath 强直性脊柱炎功能指数(Bath ankylosing spondylitis functional index, BASFI)量表和Bath 强直性 脊柱炎测量学指数(Bath ankylosing spondylitis metrology index, BASMI)], 监测安全性指标的变化。
结果
治疗1、2 个疗程后, 两组患者中医证候量化积分均较治疗前明显改善(P<0.05),治疗组改善情况优于对照组(P<0.05)。两组 组内比较, 治疗1 个疗程和2 个疗程后的评分均无统计学差异(P>0.05)。两组患者治疗1 个疗程后症状积分各项 指标均较治疗前改善(P<0.05); 治疗2 个疗程后, 治疗组的疗效更显著, 与对照组差异有统计学意义(P<0.05)。 治疗过程中两组安全性指标未发现明显异常。
结论
督灸能有效缓解AS 患者的临床症状, 无明显不良反应。
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Feng, H., Ma, Yh. & Wang, Xm. Moxibustion on Governor Vessel for ankylosing spondylitis due to kidney yang deficiency: a clinical controlled study. J. Acupunct. Tuina. Sci. 13, 361–367 (2015). https://doi.org/10.1007/s11726-015-0883-1
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DOI: https://doi.org/10.1007/s11726-015-0883-1