摘要
目的
观察针药并用治疗2 型糖尿病高血压及对血浆神经肽Y (Neuropeptide Y, NPY)的影响。
方法
将60 例2 型糖尿病高血压患者按入院顺序, 随机分为两组, 治疗组30 例, 采用针刺加口服硝苯地平缓释片治疗, 对照组30 例, 采用单纯口服硝苯地平缓释片治疗。 于治疗15 d后观察两组患者血压及其血浆NPY含量的变化。
结果
两组患者治疗后其血压和血浆NPY含量均显著降低(P<0.01), 且治疗组优于对照组(P<0.01)。
结论
针药并用对2 型糖尿病高血压患者具有明显的降低血压效果和降低血浆NPY含量的作用。
Abstract
Objective
To observe the effect of combined acupuncture and medication for hypertension due to type 2 diabetes and plasma Neuropeptide Y (NPY).
Methods
Sixty cases with hypertension due to type 2 diabetes were randomized into two groups. Thirty cases in the treatment group were treated with acupuncture and oral extended release nifedipine tablets, while 30 cases in the control group were treated with oral extended release nifedipine tablets alone. After 15 d of treatment, the blood pressure and NPY contents in two groups were observed.
Results
The blood pressure and NPY contents in the two groups were remarkably reduced (P<0.01) and the effect in the treatment group was superior to the control group (P<0.01).
Conclusion
Combined acupuncture and medication can significantly reduce blood pressure and the NPY contents.
References
The Revision Committee of Prevention and Care for Hypertension in China, Prevention and Care Guidelines for Hypertension in 2004. Chinese Journal of Hypertension, 2004, 12(6): 483–486.
Ministry of Health of the People’s Republic of China. Guiding Principles for Clinical Study of New Chinese Medicines. Beijing: China Medicine and Drugs Technology Press, 2002: 256.
CHEN Bang-guo, QIAN Chun-yan, ZHANG Jing-ning, et al. Clinical Observation on the Hypotensive Effect of Point Fengchi Acupuncture on Hypertension. Shanghai J Acu-mox, 2006, 25(3): 15–16
ZHOU Wan-xing. Neuropeptide Y and Hypertension. Foreign Medical Sciences (Section of Internal Medicine), 2000, 27(8): 342–344.
WANG Xiao-zhou, JIANG Qi-nian, YANG Yong-qing, et al. Alternations and Meaning of NPY Contents in Hypertension Patients. Jiangsu Medical Journal, 2002, 28(10): 794–795.
MIAO Qian, MIN Su. Effects and Mechanism of Neuropeptide Y on Cardiovascular System. Advances in Cardiovascular Diseases, 2005, 26(6): 602–604.
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Additional information
Fund Item: Key Program of Guangxi Healthcare (Key 2006049)
Author: PANG Sheng-hang (1955– ), male, chief physician
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Pang, Sh., Liu, Gj. & Zhao, Ws. Effect of combined acupuncture and medication for hypertension due to type 2 diabetes mellitus and plasma Neuropeptide Y. J. Acupunct. Tuina. Sci. 8, 291–294 (2010). https://doi.org/10.1007/s11726-010-0429-5
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DOI: https://doi.org/10.1007/s11726-010-0429-5