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Which Factors Correlate with Marginal Ulcer After Surgery for Obesity?

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A Correction to this article was published on 12 October 2020

This article has been updated

Abstract

Introduction

Marginal ulcer is one of the most common complications after Roux-en-Y gastric bypass and is defined as an ulceration of any depth at or near the gastrojejunal anastomosis. Different risk factors have been advocated to be the causative agent.

Materials and Methods

The weighted discharges from the Nationwide Inpatient Sample from 2003 to 2011 were used to assess for risk factors to develop marginal ulcer such as Helicobacter pylori infection, chronic nonsteroidal anti-inflammatory use, chronic aspirin use, alcohol dependence, smoking, hypertension, and diabetes mellitus type II.

Results

Chronic nonsteroidal anti-inflammatory drug use was the most significant risk factor for marginal ulcer, followed by Helicobacter pylori infection, obstructive sleep apnea, female sex, smoking, and alcohol dependence in decreasing order. Diabetes mellitus and hypertension were found to slightly increase the risk for marginal ulcer. The use of aspirin was found to be a minor risk factor during univariate analysis but a protective factor during multivariate analysis.

Conclusions

Multiple well-documented single factors are related to the genesis of a marginal ulcer, although it is likely that a combination of risk factors is responsible for this problem. These risk factors should be identified and removed or controlled.

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Change history

  • 12 October 2020

    In the original article, the author names were presented incorrectly; their family names and given names were inverted.

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Acknowledgments

We would like to thank Nicole L. Duarte for providing language help and proofreading the article.

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Authors and Affiliations

  1. Department of Medicine, Division of Gastroenterology, St. Luke’s University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA

    Duarte-Chavez Rodrigo & Chaput Kimberly

  2. Department of Research, St. Luke’s University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA

    Stoltzfus Jill

  3. Robert Wood Johnson Medical School, 1 Robert Wood Johnson place, New Brunswick, NJ, 08901, USA

    Marino Daniel

  4. Department of Surgery, Division of Bariatric Surgery, St. Luke’s University Health Network, 801 Ostrum Street, Bethlehem, PA, 18015, USA

    El Chaar Maher

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  1. Duarte-Chavez Rodrigo
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Correspondence to Duarte-Chavez Rodrigo.

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Rodrigo, DC., Jill, S., Daniel, M. et al. Which Factors Correlate with Marginal Ulcer After Surgery for Obesity?. OBES SURG 30, 4821–4827 (2020). https://doi.org/10.1007/s11695-020-04960-z

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  • DOI: https://doi.org/10.1007/s11695-020-04960-z

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