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Maternal Anthropometry and Its Relationship with the Nutritional Status of Vitamin D, Calcium, and Parathyroid Hormone in Pregnant Women After Roux-en-Y Gastric Bypass

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Abstract

Objective

To assess the influence of pre-pregnancy body mass index (BMI), total gestational weight gain (TGWG), and pre-pregnancy surgical success on the nutritional status of vitamin D, calcium, and parathyroid hormone (PTH) in the trimesters of pregnancy of women who previously underwent Roux-en-Y gastric bypass (RYGB).

Methodology

This is an analytical, longitudinal, and retrospective study comprising 42 pregnant women who previously underwent RYGB. Concentrations of vitamin D3, calcium, and PTH were assessed in all trimesters. Anthropometric variables necessary for calculating TGWG, surgical success, and BMI were collected preoperatively and over the trimesters of pregnancy.

Results

A total of 97.1% had vitamin D3 inadequacy at some point in pregnancy. Pre-pregnancy BMI, even when classified as overweight, may have exacerbated the serum concentrations of this vitamin in the third trimester (p = 0.011), and it was significantly lower in women with normal weight and/or obesity (p = 0.039). It was evidenced that both pre-pregnancy BMI and TGWG above the recommended optimal weight can be associated with calcium homeostasis, especially early in pregnancy. It was also shown that surgical success in the pre-pregnancy period may have influenced the serum concentrations of vitamin D in the second trimester of pregnancy (p = 0.013).

Conclusion

This study draws attention to the importance of monitoring the nutritional status of vitamin D3 and calcium in the prenatal period due to its relationship with pre-pregnancy BMI, TGWG, and surgical success.

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Acknowledgments

The authors acknowledge the support received from Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ, Carlos Chagas Filho Foundation for Research Support of the State of Rio de Janeiro) (Scientist of Our State).

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Authors and Affiliations

  1. School of Medicine, Federal University of Rio de Janeiro (UFRJ), Carlos Chagas avenue, 373, Edifício do Centro de Ciências da Saúde, 2° floor, room 49, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, 21941-902, Brazil

    Sabrina Cruz, Andrea Cardoso de Matos & Silvia Pereira

  2. Center for Research on Micronutrients (NPqM), Institute of Nutrition Josué de Castro of UFRJ, Rio de Janeiro, 21941-902, Brazil

    Sabrina Cruz, Andrea Cardoso de Matos, Silvia Pereira & Carlos Saboya

  3. Federal University Fluminence (UFF), Niterói, Brazil

    Andrea Cardoso de Matos

  4. Center for Research on Micronutrients (NPqM), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, 21941-902, Brazil

    Suelem Pereira da Cruz

  5. Multidisciplinary Center for Bariatric and Metabolic Surgery, Rio de Janeiro, Brazil

    Silvia Pereira & Carlos Saboya

  6. Federal University of São Paulo (UNIFESP), São Paulo, Brazil

    Carlos Saboya

  7. Brazilian Society of Bariatric and Metabolic Surgery, São Paulo, Brazil

    Carlos Saboya

  8. ENSP/FIOCRUZ, Rio de Janeiro, Brazil

    Andréa Ramalho

  9. Department of Social and Applied Nutrition, Institute of Nutrition, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil

    Andréa Ramalho

  10. Institute of Nutrition Josué de Castro, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, 21941-902, Brazil

    Andréa Ramalho

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  1. Sabrina Cruz
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Correspondence to Sabrina Cruz.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants for whom identifying information is included in this article.

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Cruz, S., de Matos, A.C., da Cruz, S.P. et al. Maternal Anthropometry and Its Relationship with the Nutritional Status of Vitamin D, Calcium, and Parathyroid Hormone in Pregnant Women After Roux-en-Y Gastric Bypass. OBES SURG 28, 3116–3124 (2018). https://doi.org/10.1007/s11695-018-3331-8

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  • DOI: https://doi.org/10.1007/s11695-018-3331-8

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