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Predictors of Excess Weight Loss in Obese Patients After Gastric Bypass: a 60-Month Follow-up

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Abstract

Background

The objective of this study was to analyze the factors associated with change in body mass index (BMI) and with percentage of excess weight loss (%EWL) in patients undergoing Roux-en-Y gastric bypass (RYGB). The following factors were analyzed: sex, age, surgical access (laparotomy vs. laparoscopy), preoperative BMI, waist circumference (WC), type 2 diabetes mellitus (T2DM), high blood pressure, and dyslipidemia.

Methods

Retrospective cohort study using a convenience sample of 2070 patients of both sexes, aged 18 to 65 years, undergoing RYGB between 2000 and 2013. The outcomes of interest were BMI and %EWL at 0, 6, 12, 18, 24, 30, 36, 42, 48, 54, and 60 months after RYGB.

Results

After 36, 48, and 60 months, approximately 50 % of patients had BMI >30 kg/m2. As for %EWL, 60-month results were poor for 17 % of patients (%EWL <50 %), good for 40 % of patients (%EWL 50–75 %), very good for 24 % of patients (%EWL from >75–90 %), and excellent for 19 % of patients (%EWL >90 %). The four most significant predictors of BMI change 60 months after RYGB (in descending order of magnitude) were preoperative BMI, preoperative WC, surgical access, and age; and of %EWL, surgical access, preoperative BMI, preoperative WC, and age.

Conclusions

After 60 months of follow-up, the most relevant predictors of weight loss after RYGB were lower preoperative BMI and WC, videolaparoscopy as surgical access, and younger age. Further studies must be carried out to elucidate the impact of these factors on RYGB outcomes.

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Authors and Affiliations

  1. Center of Obesity and Metabolic Syndrome, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (COM-PUCRS), Av. Ipiranga, 6690/302, 90610-000, Porto Alegre, RS, Brazil

    Anália S. Barhouch, Alexandre V. Padoin, Daniela S. Casagrande, Raquel Chatkin, Samanta P. Süssenbach, Milene A. Pufal, Carina Rossoni & Cláudio C. Mottin

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  1. Anália S. Barhouch
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  2. Alexandre V. Padoin
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  4. Raquel Chatkin
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  5. Samanta P. Süssenbach
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  6. Milene A. Pufal
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Correspondence to Cláudio C. Mottin.

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Financial Disclosure

The authors have no financial relationships relevant to this article to disclose.

Conflict of Interest

The authors declare that they have no competing interests.

Ethical Approval

This study was approved by the Research Ethics Committee at Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) (no. 465.360) and is in accordance with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

Informed consent is not required from retrospective studies using secondary data.

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Barhouch, A.S., Padoin, A.V., Casagrande, D.S. et al. Predictors of Excess Weight Loss in Obese Patients After Gastric Bypass: a 60-Month Follow-up. OBES SURG 26, 1178–1185 (2016). https://doi.org/10.1007/s11695-015-1911-4

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  • DOI: https://doi.org/10.1007/s11695-015-1911-4

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