Abstract
Brunner’s gland adenoma is a rare tumour of the duodenum, which is usually benign. A 71-year-old woman presenting with epigastric pain, upper gastrointestinal haemorrhage and melaena was reported in this paper. Upper gastro-intestinal (GI) endoscopy revealed a large pedunculated tumour on the superior part of the duodenal bulb. Endoscopic polypectomy was successfully performed by clipping and nylon thread without any complications. Histological examination revealed a Brunner’s gland adenoma.
Similar content being viewed by others
References
Brookes M J, Manjunatha S, Allen C A, Cox M. Malignant potential in a Brunner’s gland hamartoma. Postgrad Med J, 2003, 79(933): 416–417
Fujimaki E, Nakamura S, Sugai T, Takeda Y. Brunner’s gland adenoma with a focus of p53-positive atypical glands. J Gastroenterol, 2000, 35(2): 155–158
Matsui T, Iida M, Fujischima M, Sakamoto K, Watanabe H. Brunner’s gland hamartoma associated with microcarcinoids. Endoscopy, 1989, 21(1): 37–38
Zanetti G, Casadei G. Brunner’s gland hamartoma with incipient ductal malignancy: report of a case. Tumori, 1981, 67(1): 75–78
Christie A C. Duodenal carcinoma with neoplastic transformation of the underlying Brunner’s glands. Br J Cancer, 1953, 7(1): 65–67
Laarman G J, van der Wall E E, Muller J W, Eggink H D, Hoekstra J B. Extreme adenomatous hyperplasia of Brunner’s glands in the proximal jejunum. Neth J Med, 1988, 32(1–2): 20–26
Henken E M, Forouhar F. Hamartoma of Brunner’s gland causing obstruction of the ileum. J Can Assoc Radiol, 1983, 34(1): 73–74
Chandrasoma P. Gastrointestinal pathology. Connecticut: Appleton and Lange, 1999, 133–134
Fuller J W, Cruse C W, William J W. Hyperplasia of Brunner’s glands of the duodenum. Am Surg, 1977, 43(4): 246–250
Farkas I E, Gero G. The role of Brunner’s glands in the mucosal protection of the proximal part of the duodenum. Acta Physiol Hung, 1989, 73(2–3): 257–260
De Castella H. Brunner’s gland adenoma. An unusual cause of intestinal bleeding. Br J Surg, 1966, 53(2): 153–156
Gao Y P, Zhu J S, Zheng W J. Brunner’s gland adenoma of duodenum: a case report and literature review. Word J Gastroenterol, 2004, 10(17): 2616–2617
Yadav D, Hertan H, Pitchumoni C S. A giant Brunner’s gland adenoma presenting as gastrointestinal hemorrhage. J Clin Gastroenterol, 2001, 32(5): 448–450
Shah A B, Muzumdar G A, Chitale A R. Giant Brunneroma. Bombay Hospital Journal, 2005, 4: 47 (2)
Feyrter F. Uberwucherungen der Brunnerschen drusen. Virchows Arch, 1934, 293: 509
Peetz M E, Moseley H S. Brunner’s gland hyperplasia. Am Surg, 1989, 55(7): 474–477
Jansen J M, Stuifbergen W N, van Milligen de Wit A W. Endoscopic resection of a large Brunner’s gland adenoma. Neth J Med, 2002, 60(6): 253–255
Zhang J P, Zhou D Q, Li X B. Brunner’s gland adenoma in duodenum. Shanxi Yike Daxue Xuebao, 1999, 30(2): 192–193 (in Chinese)
Rocco A, Borriello P, Compare D, De Colibus P, Pica L, Iacono A, Nardone G. Large Brunner’s gland adenoma: Case report and literature review. World J Gastroenterol, 2006, 12(12): 1966–1968
Spellberg M A, Vucelic B. A case of Brunner’s glands hyperplasia with diarrhea responsive to cimetidine. Am J Gastroenterol, 1980, 73(6): 519–522
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Zhang, B., Ren, X., Tang, X. et al. Endoscopic resection of a huge Brunner’s gland adenoma. Front. Med. China 2, 414–418 (2008). https://doi.org/10.1007/s11684-008-0080-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11684-008-0080-4