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Get Screened: A Randomized Trial of the Incremental Benefits of Reminders, Recall, and Outreach on Cancer Screening

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A Capsule Commentary to this article was published on 03 October 2013

ABSTRACT

BACKGROUND

Rates of breast cancer (BC) and colorectal cancer (CRC) screening are particularly low among poor and minority patients. Multifaceted interventions have been shown to improve cancer-screening rates, yet the relative impact of the specific components of these interventions has not been assessed. Identifying the specific components necessary to improve cancer-screening rates is critical to tailor interventions in resource limited environments.

OBJECTIVE

To assess the relative impact of various components of the reminder, recall, and outreach (RRO) model on BC and CRC screening rates within a safety net practice.

DESIGN

Pragmatic randomized trial.

PARTICIPANTS

Men and women aged 50–74 years past due for CRC screen and women aged 40–74 years past due for BC screening.

INTERVENTIONS

We randomized 1,008 patients to one of four groups: (1) reminder letter; (2) letter and automated telephone message (Letter + Autodial); (3) letter, automated telephone message, and point of service prompt (Letter + Autodial + Prompt); or (4) letter and personal telephone call (Letter + Personal Call).

MAIN MEASURES

Documentation of mammography or colorectal cancer screening at 52 weeks following randomization.

KEY RESULTS

Compared to a reminder letter alone, Letter + Personal Call was more effective at improving screening rates for BC (17.8 % vs. 27.5 %; AOR 2.2, 95 % CI 1.2–4.0) and CRC screening (12.2 % vs. 21.5 %; AOR 2.0, 95 % CI 1.1–3.9). Compared to letter alone, a Letter + Autodial + Prompt was also more effective at improving rates of BC screening (17.8 % vs. 28.2 %; AOR 2.1, 95 % CI 1.1–3.7) and CRC screening (12.2 % vs. 19.6 %; AOR 1.9, 95 % CI 1.0–3.7). Letter + Autodial was not more effective than a letter alone at improving screening rates.

CONCLUSIONS

The addition of a personal telephone call or a patient-specific provider prompt were both more effective at improving mammogram and CRC screening rates compared to a reminder letter alone. The use of automated telephone calls, however, did not provide any incremental benefit to a reminder letter alone.

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REFERENCES

  1. Cancer screening—United States, 2010. MMWR Morb Mortal Wkly Rep. 2012;61(3):41–5.

  2. Sabatino SA, Lawrence B, Elder R, et al. Effectiveness of interventions to increase screening for breast, cervical, and colorectal cancers: nine updated systematic reviews for the guide to community preventive services. Am J Prev Med. 2012;43(1):97–118. doi:10.1016/j.amepre.2012.1004.1009.

    Article  PubMed  Google Scholar 

  3. Brouwers MC, De Vito C, Bahirathan L, et al. What implementation interventions increase cancer screening rates? A systematic review. Implement Sci. 2011;6:111. doi:10.1186/1748-5908-1186-1111.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Rodewald LE, Szilagyi PG, Humiston SG, Barth R, Kraus R, Raubertas RF. A randomized study of tracking with outreach and provider prompting to improve immunization coverage and primary care. Pediatrics. 1999;103(1):31–8.

    Article  CAS  PubMed  Google Scholar 

  5. Fiscella K, Humiston S, Hendren S, et al. A multimodal intervention to promote mammography and colorectal cancer screening in a safety-net practice. J Natl Med Assoc. 2011;103(8):762–8.

    PubMed  Google Scholar 

  6. Fiscella K, Yosha A, Hendren SK, et al. Get screened: a pragmatic randomized controlled trial to increase mammography and colorectal cancer screening in a large, safety net practice. BMC Health Serv Res. 2010;10:280. doi:10.1186/1472-6963-1110-1280.

    Article  PubMed Central  PubMed  Google Scholar 

  7. Hendren S, Winters P, Humiston S, et al. Randomized controlled trial of a multimodal intervention to improve cancer screening rates in a safety-net primary care practice. JGIM. 2013. doi:10.1007/s11606-013-2506-1.

  8. U.S. Census Bureau: State and County QuickFacts. Data derived from Population Estimates, American Community Survey, Census of Population and Housing, County Business Patterns, Economic Census, Survey of Business Owners, Building Permits, Consolidated Federal Funds Report, Census of Governments 2012; http://quickfacts.census.gov/qfd/states/36/3663000.html. Accessed 7/27/2013.

  9. Qaseem A, Denberg TD, Hopkins RH Jr, et al. Screening for colorectal cancer: a guidance statement from the American College of Physicians. Ann Intern Med. 2012;156(5):378–86.

    Article  PubMed  Google Scholar 

  10. Smith RA, Cokkinides V, Brooks D, Saslow D, Brawley OW. Cancer screening in the United States, 2010: a review of current American Cancer Society guidelines and issues in cancer screening. CA Cancer J Clin. 2010;60(2):99–119.

    Article  PubMed  Google Scholar 

  11. Sequist TD, Zaslavsky AM, Marshall R, Fletcher RH, Ayanian JZ. Patient and physician reminders to promote colorectal cancer screening: a randomized controlled trial. Arch Intern Med. 2009;169(4):364–71. doi:10.1001/archinternmed.2008.1564.

    Article  PubMed Central  PubMed  Google Scholar 

  12. Baron RC, Melillo S, Rimer BK, et al. Intervention to increase recommendation and delivery of screening for breast, cervical, and colorectal cancers by healthcare providers a systematic review of provider reminders. Am J Prev Med. 2010;38(1):110–7. doi:10.1016/j.amepre.2009.1009.1031.

    Article  PubMed  Google Scholar 

  13. Khankari K, Eder M, Osborn CY, et al. Improving colorectal cancer screening among the medically underserved: a pilot study within a federally qualified health center. J Gen Intern Med. 2007;22(10):1410–4.

    Article  PubMed Central  PubMed  Google Scholar 

  14. Ling BS, Schoen RE, Trauth JM, et al. Physicians encouraging colorectal screening: a randomized controlled trial of enhanced office and patient management on compliance with colorectal cancer screening. Arch Intern Med. 2009;169(1):47–55.

    Article  PubMed  Google Scholar 

  15. Lasser KE, Murillo J, Lisboa S, et al. Colorectal cancer screening among ethnically diverse, low-income patients: a randomized controlled trial. Arch Intern Med. 2011;171(10):906–12.

    Article  PubMed  Google Scholar 

  16. Segnan N, Senore C, Andreoni B, et al. Randomized trial of different screening strategies for colorectal cancer: patient response and detection rates. J Natl Cancer Inst. 2005;97(5):347–57.

    Article  PubMed  Google Scholar 

  17. Sequist TD, Zaslavsky AM, Colditz GA, Ayanian JZ. Electronic patient messages to promote colorectal cancer screening: a randomized controlled trial. Arch Intern Med. 2011;171(7):636–41. doi:10.1001/archinternmed.2010.1467. Epub 2010 Dec 1013.

    Article  PubMed Central  PubMed  Google Scholar 

  18. Swan J, Breen N, Coates RJ, Rimer BK, Lee NC. Progress in cancer screening practices in the United States: results from the 2000 National Health Interview Survey. Cancer. 2003;97(6):1528–40.

    Article  PubMed  Google Scholar 

  19. Feldstein AC, Perrin N, Rosales AG, et al. Effect of a multimodal reminder program on repeat mammogram screening. Am J Prev Med. 2009;37(2):94–101.

    Article  PubMed Central  PubMed  Google Scholar 

  20. Phillips CE, Rothstein JD, Beaver K, Sherman BJ, Freund KM, Battaglia TA. Patient navigation to increase mammography screening among inner city women. J Gen Intern Med. 2011;26(2):123–9.

    Article  PubMed Central  PubMed  Google Scholar 

  21. Agency for Healthcare Research and Quality. Patient Centered Medical Home Resource Center. http://pcmh.ahrq.gov. Accessed 7/27/2013.

  22. Dietrich AJ, Tobin JN, Cassells A, et al. Telephone care management to improve cancer screening among low-income women: a randomized, controlled trial. Ann Intern Med. 2006;144(8):563–71.

    Article  PubMed Central  PubMed  Google Scholar 

  23. Green BB, Wang CY, Anderson ML, et al. An automated intervention with stepped increases in support to increase uptake of colorectal cancer screening: a randomized trial. Ann Intern Med. 2013;158(5 Pt 1):301–11. doi:10.7326/0003-4819-7158-7325-201303050-201300002.

    Article  PubMed  Google Scholar 

  24. Kempe KL, Shetterly SM, France EK, Levin TR. Automated phone and mail population outreach to promote colorectal cancer screening. Am J Manag Care. 2012;18(7):370–8.

    PubMed  Google Scholar 

  25. Car J, Gurol-Urganci I, de Jongh T, Vodopivec-Jamsek V, Atun R. Mobile phone messaging reminders for attendance at healthcare appointments. Cochrane Database Syst Rev. 2012;7, CD007458.

    PubMed  Google Scholar 

  26. Hines P, Mercury M. Designing the role of the embedded care manager. Prof Case Manag. 2013;18(4):182–7.

    Article  PubMed  Google Scholar 

  27. Freeman HP. The history, principles, and future of patient navigation: commentary. Semin Oncol Nurs. 2013;29(2):72–5.

    Article  PubMed  Google Scholar 

  28. Ishikawa Y, Hirai K, Saito H, et al. Cost-effectiveness of a tailored intervention designed to increase breast cancer screening among a non-adherent population: a randomized controlled trial. BMC Publ Health. 2012;12:760. doi:10.1186/1471-2458-1112-1760.

    Article  Google Scholar 

  29. Lee JK, Groessl EJ, Ganiats TG, Ho SB. Cost-effectiveness of a mailed educational reminder to increase colorectal cancer screening. BMC Gastroenterol. 2011;11:93. doi:10.1186/1471-1230X-1111-1193.

    Article  PubMed Central  PubMed  Google Scholar 

  30. Misra S, Lairson DR, Chan W, et al. Cost effectiveness of interventions to promote screening for colorectal cancer: a randomized trial. J Prev Med Public Health. 2011;44(3):101–10. doi:10.3961/jpmph.2011.3944.3963.3101.

    Article  PubMed  Google Scholar 

  31. Saywell RM Jr, Champion VL, Skinner CS, Menon U, Daggy J. A cost-effectiveness comparison of three tailored interventions to increase mammography screening. J Womens Health (Larchmt). 2004;13(8):909–18.

    Article  Google Scholar 

  32. Sequist TD, Franz C, Ayanian JZ. Cost-effectiveness of patient mailings to promote colorectal cancer screening. Med Care. 2010;48(6):553–7. doi:10.1097/MLR.1090b1013e3181dbd1098eb.

    Article  PubMed Central  PubMed  Google Scholar 

  33. Smith DH, Feldstein AC, Perrin N, et al. Automated telephone calls to enhance colorectal cancer screening: economic analysis. Am J Manag Care. 2012;18(11):691–9.

    PubMed Central  PubMed  Google Scholar 

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Acknowledgments

Contributors

All authors listed have contributed sufficiently to the project to be included as authors, and all those who are qualified to be authors are listed in the author byline.

Grant Support

This project was supported by the American Cancer Society - RSGT-08-077-01-CPHPS.

Conflict of Interest

The authors declare that they do not have a conflict of interest.

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Corresponding author

Correspondence to Kevin Fiscella MD, MPH.

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Fortuna, R.J., Idris, A., Winters, P. et al. Get Screened: A Randomized Trial of the Incremental Benefits of Reminders, Recall, and Outreach on Cancer Screening. J GEN INTERN MED 29, 90–97 (2014). https://doi.org/10.1007/s11606-013-2586-y

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