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Pathogen Analysis of Superficial Mucocutaneous Mycosis in a Tertiary A-level Hospital from 2007 to 2018

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Abstract

Objective

This study aimed to analyze the fungal species of pathogens isolated from patients with superficial mucocutaneous mycosis from May 2007 to December 2018.

Methods

A retrospective analysis was carried out to determine the pathogenic fungi isolated from patients with superficial fungal infections in the Medical Mycology Clinical Laboratory, Department of Dermatology and Venereology, Union Hospital, from May 2007 to December 2018.

Results

A total of 7639 strains were obtained, belonging to 21 genera and 36 species. They mainly consisted of Candida (3707/7639, 48.53%) and dermatophytes (3594/7639, 47.05%). The specimens were skin scales, nail shavings, secretions on the nail grooves, broken or diseased hair and dandruff, secretions or pseudomembrane of the external genitalia, and the oral mucosa. A total of 7300 patients were enrolled in this study, including 3301 males and 3999 females aged 2 months to 92 years old with a median age of 46.04 years old except for 633 patients whose ages were unknown. Two strains of different species were isolated from each of 339 patients at different body sites. The most frequent species were Trichophyton rubrum complex (2906/7639, 38.04%), Candida albicans (2619/7639, 34.28%), and unclassified Candida spp. Dermatophytes were mostly isolated from glabrous skin (2138/3594, 59.49%), with T. rubrum complex being the predominant species. Candida strains were most commonly isolated from mucosal sites (1979/3707, 53.39%), and C. albicans was the most prevalent causative agent.

Conclusion

The main distribution of pathogenic fungal species isolated from patients with superficial mycosis from 2007 to 2018 in Wuhan, Hubei province and the surrounding areas was that Candida slightly outnumbered dermatophytes. Among all of the isolated strains, T. rubrum complex was the most abundant.

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Author notes

  1. The authors contributed equally to this work.

Authors and Affiliations

  1. Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China

    Ting Wu, Shi-di Wu, Ling-yun Zhang, Hai-hua Ye, Ye-hong Mao, Xin Lian, Juan Tao, Chang-zheng Huang & Jing-si Zeng

Authors
  1. Ting Wu
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  2. Shi-di Wu
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  3. Ling-yun Zhang
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  4. Hai-hua Ye
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  5. Ye-hong Mao
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  6. Xin Lian
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  7. Juan Tao
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  8. Chang-zheng Huang
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  9. Jing-si Zeng
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Corresponding authors

Correspondence to Chang-zheng Huang or Jing-si Zeng.

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The authors declare that they have no conflicts of interest.

Author Juan TAO is a member of the Editorial Board for Current Medical Science. The paper was handled by the other editor and has undergone rigorous peer review process. Author Juan TAO was not involved in the journal’s review of, or decision related to, this manuscript.

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Wu, T., Wu, Sd., Zhang, Ly. et al. Pathogen Analysis of Superficial Mucocutaneous Mycosis in a Tertiary A-level Hospital from 2007 to 2018. CURR MED SCI 42, 434–438 (2022). https://doi.org/10.1007/s11596-022-2576-7

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  • DOI: https://doi.org/10.1007/s11596-022-2576-7

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