Summary
Risk factors for adverse pregnancy outcomes among Zhuang ethnic pregnant women are unclear. This study analyzed the incidence and risk factors related to preterm birth (PB), low birth weight (LBW) and macrosomia in Zhuang population. We conducted a prospective cohort study of 9965 Zhuang pregnancy women in Guangxi, China. Information on mothers and newborns was obtained by using questionnaires and referring to medical records. Multivariate logistic regression analyses were used to evaluate the association between related factors and adverse pregnancy outcomes. Our results showed that the incidence of PB, LBW and macrosomia in Zhuang people was 5.55%, 5.64% and 2.19%, respectively. Maternal age ≥36 years (OR=2.22, 95% CI: 1.51–3.27) was related to a higher incidence of PB. Those with pre-pregnancy body mass index (BMI) <18.5 kg/m2 (OR=1.91, 95% CI: 1.45–2.51), and had a female fetus (OR=1.74, 95% CI: 1.36–2.23) were more likely to have LBW infants. Maternal age between 31 and 35 years (OR=1.76, 95% CI: 1.03–2.99) and pre-pregnancy overweight or obesity (OR=1.79, 95% CI: 1.15–2.80) were associated with a higher risk of macrosomia. The protective factors of macrosomia were maternal pre-pregnancy BMI <18.5 kg/m2 (OR=0.30, 95% CI: 0.15–0.60) and female fetus (OR=0.41, 95% CI: 0.28–0.59). Our study provided a reference for maternal and childcare administration among Zhuang population.
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Acknowledgments
We are grateful to the pregnant women in the study, the research team from School of Public Health at Guangxi Medical University, and the medical staffs of 13 hospitals, including Jingxi People’s Hospital, Jingxi Maternity and Child Health Care Hospital, Longan People’s Hospital, Tiandong People’s Hospital, Tiandong Maternity and Child Health Care Hospital, Tianyang People’s Hospital, Tianyang Maternity and Child Health Care Hospital, Pingguo People’s Hospital, Pingguo Maternity and Child Health Care Hospital, Debao People’s Hospital, Debao Maternity and Child Health Care Hospital, Wuming People’s Hospital, and Wuming Maternity and Child Health Care Hospital.
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The authors report no conflicts of interest in this study.
This project was supported by grants from the National Natural Science Foundation of China (No. 21906032 and No. 81903285), China Postdoctoral Science Foundation (No. 2020M673556XB), Youth Science Foundation of Guangxi Medical University (No. GXMUYSF201822) and the Guangxi Key Research Program (No. AB17195012).
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Feng, By., Peng, Y., Liang, J. et al. Risk Factors for Adverse Pregnancy Outcomes among Zhuang Ethnic Pregnant Women: A Cohort Study in Guangxi, China. CURR MED SCI 41, 219–227 (2021). https://doi.org/10.1007/s11596-021-2339-9
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DOI: https://doi.org/10.1007/s11596-021-2339-9