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mResU-Net: multi-scale residual U-Net-based brain tumor segmentation from multimodal MRI

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Abstract

Brain tumor segmentation is an important direction in medical image processing, and its main goal is to accurately mark the tumor part in brain MRI. This study proposes a brand new end-to-end model for brain tumor segmentation, which is a multi-scale deep residual convolutional neural network called mResU-Net. The semantic gap between the encoder and decoder is bridged by using skip connections in the U-Net structure. The residual structure is used to alleviate the vanishing gradient problem during training and ensure sufficient information in deep networks. On this basis, multi-scale convolution kernels are used to improve the segmentation accuracy of targets of different sizes. At the same time, we also integrate channel attention modules into the network to improve its accuracy. The proposed model has an average dice score of 0.9289, 0.9277, and 0.8965 for tumor core (TC), whole tumor (WT), and enhanced tumor (ET) on the BraTS 2021 dataset, respectively. Comparing the segmentation results of this method with existing techniques shows that mResU-Net can significantly improve the segmentation performance of brain tumor subregions.

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Data availability

The datasets are provided by BraTS 2021 Challenge and are allowed for personal academic research. The specific link to the dataset is https://ipp.cbica.upenn.edu/.

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Funding

(1) FC (No.61972117); (2) the Natural Science Foundation of Heilongjiang Province of China (ZD2019E007).

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Correspondence to Pengcheng Li.

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Li, P., Li, Z., Wang, Z. et al. mResU-Net: multi-scale residual U-Net-based brain tumor segmentation from multimodal MRI. Med Biol Eng Comput 62, 641–651 (2024). https://doi.org/10.1007/s11517-023-02965-1

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