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Sesquiterpenes from Curcuma comosa

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Abstract

From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7α-hydroxyneocurdione, 7β-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.

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Acknowledgments

This research was supported by the 21st COE Program, Academic Frontier Project, and a Grant-in-Aid for Scientific Research from MEXT (the Ministry of Education, Culture, Sports, Science and Technology of Japan).

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Authors and Affiliations

  1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China

    Yang Qu & Lijun Wu

  2. Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412, Japan

    Fengming Xu, Seikou Nakamura, Hisashi Matsuda & Masayuki Yoshikawa

  3. Rajamangala University of Technology Srivijaya, Thungyai, Nakhon Si Thammarat, 80240, Thailand

    Yutana Pongpiriyadacha

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  1. Yang Qu
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  2. Fengming Xu
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  3. Seikou Nakamura
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  4. Hisashi Matsuda
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  5. Yutana Pongpiriyadacha
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  6. Lijun Wu
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  7. Masayuki Yoshikawa
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Correspondence to Masayuki Yoshikawa.

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Qu, Y., Xu, F., Nakamura, S. et al. Sesquiterpenes from Curcuma comosa . J Nat Med 63, 102–104 (2009). https://doi.org/10.1007/s11418-008-0282-8

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  • DOI: https://doi.org/10.1007/s11418-008-0282-8

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