Abstract
Microfluidics has great potential as an efficient tool for a large range of applications in industry. The ability of such devices to deal with an extremely small amount of fluid has additional benefits, including superlatively fast and efficient mass and heat transfer. These characteristics of microfluidics have attracted an enormous amount of interest in their use as a novel tool for lipid production and modification. In addition, lipid resources have a close relationship with energy resources, and lipids are an alternative renewable energy source. Here, recent advances in the application of microfluidics for lipid production and modification, especially in the discovery, culturing, harvesting, separating, and monitoring of lipid-producing microorganisms, will be reviewed. Other applications of microfluidics, such as the modification of lipids from microorganisms, will also be discussed. The novel microfluidic tools in this review will be useful in applications to improve lipid production and modification in the future.
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Funding
This study was financially supported by the Key Research and Development Program (Modern Agriculture) of Jiangsu Province (BE2017322), the Key Research and Development Program (Modern Agriculture) of Zhenjiang City (NY2017010), the Six Talent Peaks Project of Jiangsu Province (2015-NY-018), the 333 High-level Talent Training Project of Jiangsu Province (Year 2018), the Shen Lan Young scholars program of Jiangsu University of Science and Technology (Year 2015), and the Postgraduate Research and Practice Innovation Programs of Jiangsu Province (KYCX18_2305, SJKY19_2670).
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Wang, JZ., Zhu, LL., Zhang, F. et al. Microfluidic tools for lipid production and modification: a review. Environ Sci Pollut Res 26, 35482–35496 (2019). https://doi.org/10.1007/s11356-019-05833-4
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DOI: https://doi.org/10.1007/s11356-019-05833-4